Inside Higher Ed
Research Scientist, Biochemistry
Inside Higher Ed, Stanford, California, United States, 94305
Overview
Research Scientist, Biochemistry role at Inside Higher Ed. The position is a 2-year fixed term with possible extension based on performance and budget. Sarafan ChEM-H is an interdisciplinary institute at Stanford focusing on connecting Chemistry, Engineering, and Medicine for Human Health. The Functional Protein Observatory initiative aims to develop large datasets describing protein function to inform future AI models. Position Summary: Sarafan ChEM-H is seeking a highly motivated scientist to serve as the Research Scientist, Biochemistry, as a key member of the Functional Protein Observatory team. The Research Scientist will report to the faculty Director of the Functional Protein Observatory. The role involves testing, validating, refining, and applying high-throughput platforms to measure protein function across libraries, with training in protein biochemistry, molecular biology, and analysis of large datasets. Distribution Of Responsibilities
Approximately 20% of time on biochemical assay validation and molecular biology, including cloning, site-directed mutagenesis, and analytical techniques (SDS-PAGE, western blot) to verify protein expression or labeling. Approximately 20% of time on microfluidic device operation and fabrication of materials, including manufacturally spectrally-encoded beads using microfluidic devices, under guidance and later independently. Approximately 30% of time on conducting high-throughput functional assays, including large-scale screens using spectrally-encoded beads to measure binding, specificity, stability, and related parameters. Approximately 10% of time on computational analysis and data interpretation, including processing next-generation sequencing and flow cytometry data and analyzing raw datasets to assess data quality and validate workflows. Approximately 10% of time on process development and documentation, including developing rigorous, detailed, and optimized SOPs to limit variability and ensure robust datasets. Approximately 10% of time on mentoring and collaborating with other researchers, bioinformaticians, and engineers within the Observatory and other tasks as assigned. General Duties
Apply scientific and technical skills to conduct experiments generating large amounts of data related to protein function. Independently run, monitor, and troubleshoot molecular biology and biochemical assays. Quickly learn new technical skills and adopt new technologies. Document and critically review experimental approaches, develop best-practice SOPs, and present experimental data in a timely manner. Train and mentor junior staff and students on established protocols and technologies as needed. Qualifications
Education & Experience Ph.D. in Biochemistry, Molecular Biology, Bioengineering, Chemical Engineering, Biophysics or a related field with three years of relevant experience. Knowledge, Skills And Abilities Experience with protein biochemistry techniques, including protein expression, purification, and characterization. Proficiency in molecular biology, including molecular cloning and PCR/qPCR. Competency in DNA sequencing, including bioinformatics, programming (Python), statistical analysis, and data management. Strong analytical and problem-solving skills, including the ability to critically analyze datasets and workflows, identify bottlenecks and sources of variability, and troubleshoot effectively. Excellent organizational skills, strong attention to detail, and the ability to complete detailed work accurately. Ability to mentor others in workflows, SOPs, and data analysis to incorporate proteomic assays and platforms into research programs. Capacity to identify gaps and implement new processes to enhance workflows. Comprehensive understanding of scientific principles. Ability to work under strict deadlines with guidance is essential. Compensation and Benefits The expected pay range for this position is $125,000 to $145,000 per annum. Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The actual pay offered will be determined based on factors such as the scope and responsibilities of the position, qualifications, departmental budget, internal equity, geographic location, and external market pay for comparable jobs. Base pay is one aspect of the comprehensive rewards package. The Cardinal at Work website provides detailed information on benefits and rewards. Specifics about the rewards package may be discussed during the hiring process. Note: Equal Employment Opportunity statements and reasonable accommodations are included per university policy. Additional Information
Schedule: Full-time Job Code: 5574 Employee Status: Fixed-Term Grade: R99 Requisition ID: 107512 Work Arrangement: On Site Location
Stanford University, Stanford, CA
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Research Scientist, Biochemistry role at Inside Higher Ed. The position is a 2-year fixed term with possible extension based on performance and budget. Sarafan ChEM-H is an interdisciplinary institute at Stanford focusing on connecting Chemistry, Engineering, and Medicine for Human Health. The Functional Protein Observatory initiative aims to develop large datasets describing protein function to inform future AI models. Position Summary: Sarafan ChEM-H is seeking a highly motivated scientist to serve as the Research Scientist, Biochemistry, as a key member of the Functional Protein Observatory team. The Research Scientist will report to the faculty Director of the Functional Protein Observatory. The role involves testing, validating, refining, and applying high-throughput platforms to measure protein function across libraries, with training in protein biochemistry, molecular biology, and analysis of large datasets. Distribution Of Responsibilities
Approximately 20% of time on biochemical assay validation and molecular biology, including cloning, site-directed mutagenesis, and analytical techniques (SDS-PAGE, western blot) to verify protein expression or labeling. Approximately 20% of time on microfluidic device operation and fabrication of materials, including manufacturally spectrally-encoded beads using microfluidic devices, under guidance and later independently. Approximately 30% of time on conducting high-throughput functional assays, including large-scale screens using spectrally-encoded beads to measure binding, specificity, stability, and related parameters. Approximately 10% of time on computational analysis and data interpretation, including processing next-generation sequencing and flow cytometry data and analyzing raw datasets to assess data quality and validate workflows. Approximately 10% of time on process development and documentation, including developing rigorous, detailed, and optimized SOPs to limit variability and ensure robust datasets. Approximately 10% of time on mentoring and collaborating with other researchers, bioinformaticians, and engineers within the Observatory and other tasks as assigned. General Duties
Apply scientific and technical skills to conduct experiments generating large amounts of data related to protein function. Independently run, monitor, and troubleshoot molecular biology and biochemical assays. Quickly learn new technical skills and adopt new technologies. Document and critically review experimental approaches, develop best-practice SOPs, and present experimental data in a timely manner. Train and mentor junior staff and students on established protocols and technologies as needed. Qualifications
Education & Experience Ph.D. in Biochemistry, Molecular Biology, Bioengineering, Chemical Engineering, Biophysics or a related field with three years of relevant experience. Knowledge, Skills And Abilities Experience with protein biochemistry techniques, including protein expression, purification, and characterization. Proficiency in molecular biology, including molecular cloning and PCR/qPCR. Competency in DNA sequencing, including bioinformatics, programming (Python), statistical analysis, and data management. Strong analytical and problem-solving skills, including the ability to critically analyze datasets and workflows, identify bottlenecks and sources of variability, and troubleshoot effectively. Excellent organizational skills, strong attention to detail, and the ability to complete detailed work accurately. Ability to mentor others in workflows, SOPs, and data analysis to incorporate proteomic assays and platforms into research programs. Capacity to identify gaps and implement new processes to enhance workflows. Comprehensive understanding of scientific principles. Ability to work under strict deadlines with guidance is essential. Compensation and Benefits The expected pay range for this position is $125,000 to $145,000 per annum. Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The actual pay offered will be determined based on factors such as the scope and responsibilities of the position, qualifications, departmental budget, internal equity, geographic location, and external market pay for comparable jobs. Base pay is one aspect of the comprehensive rewards package. The Cardinal at Work website provides detailed information on benefits and rewards. Specifics about the rewards package may be discussed during the hiring process. Note: Equal Employment Opportunity statements and reasonable accommodations are included per university policy. Additional Information
Schedule: Full-time Job Code: 5574 Employee Status: Fixed-Term Grade: R99 Requisition ID: 107512 Work Arrangement: On Site Location
Stanford University, Stanford, CA
#J-18808-Ljbffr