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Inside Higher Ed

Post-Doc Research Associate-Bhatt Lab

Inside Higher Ed, Chapel Hill, North Carolina, United States, 27517

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Position Title:

Post-Doc Research Associate-Bhatt Lab

Location:

Chapel Hill, NC

Duration:

12 Months

Employment Type:

Full‑time, Temporary 40 hours/week

Hiring Range:

Dependent on experience and/or qualifications

Position Summary The Bhatt Lab at UNC Chapel Hill is seeking motivated, talented and creative scientists with demonstrable bioanalytical expertise to join our team. In our lab, we are advancing precision medicine by studying the gut microbiome which contributes to interindividual variability in drug responses, including efficacy and toxicity. By studying bacterial drug metabolism, we will develop strategies to predict and prevent drug‑induced injury and reduce medication side effects, thus promoting public health. The candidate will have a strong background in bioanalytical techniques and method development using a variety of platforms including LC‑MS/MS, HPLC, etc. The central role for the candidate is in developing assays to quantify metabolites of drug metabolism generated by gut microbes and the host using tandem LC‑MS/MS methodology. The candidate will also provide support for method development to the UNC Dept. Of Mass Spectrometry Core laboratory, directed by Dr. Brandie Ehrmann.

Minimum Education And Experience Requirements PhD in Chemistry, Pharmacology, Analytical Chemistry, or a related field with relevant publications in the field.

Required Qualifications, Competencies, And Experience The Research Scientist will design and perform experiments, analyze and interpret data, and disseminate research findings through written manuscripts, grant applications, and oral presentations. This role includes a significant focus on quantitative mass spectrometry, requiring expertise in handling and analyzing complex datasets. The ideal candidate will have a strong background in mass spectrometry and wet‑lab techniques, along with experience in mentoring and training undergraduate students.

Key Responsibilities

Design and conduct quantitative mass spectrometry experiments. Perform sample extraction and preparation from biological matrices.

Analyze and interpret complex data sets, including quantitative mass spectrometry data. Utilize modern mass spectrometry equipment and software.

Prepare and present research findings through written manuscripts, grant proposals, and oral presentations at lab meetings, local, national, and international conferences.

Work effectively with undergraduate students, providing training and guidance in laboratory techniques and data analysis.

Troubleshoot and maintain mass spectrometry and chromatography equipment. Ensure proper functioning of laboratory instruments.

Address and resolve experimental challenges independently. Relate experimental outcomes to the broader research context.

Read and interpret published manuscripts and experimental protocols, adapting methods for laboratory use.

Qualifications

Ph.D. in Chemistry, Pharmacology, Analytical Chemistry, or a related field with recent research laboratory experience.

Knowledge of modern mass spectrometer equipment and software from various vendors and recent hands‑on experience with mass spectrometry.

Proficiency in pipetting, sample extraction, and preparation from biological matrices.

Experience working with large mass‑spectrometry‑derived datasets.

Demonstrated ability to work independently and solve complex experimental problems.

Strong written and oral communication skills; experience with manuscript preparation and grant writing.

Proven ability to train and work constructively with diverse laboratory personnel.

Willingness to work occasional long hours as research demands.

Preferred Qualifications Experience in drug metabolism, intestinal biology/physiology, epithelial biology/physiology, or stem cell biology/physiology. Prior experience operating mass spectrometry and liquid chromatography instrumentation. Quantitative mass spectrometry experience utilizing tandem mass spectrometers is a significant bonus.

Special Physical/Mental Requirements

Must be able to complete repetitive tasks.

May require nights/weekends/after‑hours work based on sample/experimental needs.

Must be able to work in a collaborative environment.

Special Instructions For information on UNC Postdoctoral Benefits and Services, please see the university website.

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