Bristol Myers Squibb
Direct message the job poster from Bristol Myers Squibb
Work schedule Work schedule: M - F core business hours
Top 3 to 5 skills / must haves
Tissue/cell Culture
Flow Cytometry
CAR-T is a plus
Responsibilities
Spends a majority of the time working in the lab independently executing experiments and recording detailed ELN entries
Proactively communicates and aligns with team members to achieve results and support cross-functional activities
Works diligently within the team to develop and optimize non-viral gene editing platform protocols and implement new technologies for continuous improvement
Routinely generates CAR-T cells including non-viral gene editing, expansion, and cryopreservation of engineered cells
Independently analyses and interprets experimental data, experience with large and complex datasets a plus(e.g., next‑gen sequencing)
Thoroughly characterizes engineered CAR‑T cells including phenotypic analysis via flow cytometry, in‑vitro cytotoxicity assays (e.g., Incucyte), and genomic DNA extraction for downstream molecular analysis
Leverages their knowledge of molecular biology for in silico design of DNA sequences of large and complex engineered cargo in coordination with the molecular engineering team
Actively troubleshoots routine problems and initiatives related to continuous improvement or development of new approaches / technologies
Generates key data to support decisions that impact the larger team
Presents findings in multidisciplinary meetings, logically explaining complex scientific concepts and clearly highlighting key messages
May represent department or team on program/project team or sub‑team
Basic Qualifications
Bachelors Degree (5+ years of academic and / or industry experience) Or
Masters Degree (3+ years of academic and / or industry experience) Or
Ph.D. or equivalent advanced degree in the Life Sciences (No experience necessary)
Preferred Qualifications
Experience culturing T cells including aseptic technique, T cell activation, and maintenance of primary cell cultures
Experience with multi‑color flowcytometry including complex panel design and multi‑parameter data analysis (FlowJo)
Hands‑on experience with gene editing technologies (CRISPR/Cas9 preferred)
Strong knowledge of molecular biology and prior experience with DNA design tools such as Benchling, SnapGene, etc.
Experience designing and generating libraries for pooled screens and/or developing automated screening platforms
Ability to effectively multi‑task, independently organize time, and can develop timelines and deliver results accordingly
Demonstrated ability to work within a team and thrive in a fast‑paced and ever‑changing environment
Detail oriented with excellent verbal and written communication skills and careful documentation (prior ELN experience a plus)
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Work schedule Work schedule: M - F core business hours
Top 3 to 5 skills / must haves
Tissue/cell Culture
Flow Cytometry
CAR-T is a plus
Responsibilities
Spends a majority of the time working in the lab independently executing experiments and recording detailed ELN entries
Proactively communicates and aligns with team members to achieve results and support cross-functional activities
Works diligently within the team to develop and optimize non-viral gene editing platform protocols and implement new technologies for continuous improvement
Routinely generates CAR-T cells including non-viral gene editing, expansion, and cryopreservation of engineered cells
Independently analyses and interprets experimental data, experience with large and complex datasets a plus(e.g., next‑gen sequencing)
Thoroughly characterizes engineered CAR‑T cells including phenotypic analysis via flow cytometry, in‑vitro cytotoxicity assays (e.g., Incucyte), and genomic DNA extraction for downstream molecular analysis
Leverages their knowledge of molecular biology for in silico design of DNA sequences of large and complex engineered cargo in coordination with the molecular engineering team
Actively troubleshoots routine problems and initiatives related to continuous improvement or development of new approaches / technologies
Generates key data to support decisions that impact the larger team
Presents findings in multidisciplinary meetings, logically explaining complex scientific concepts and clearly highlighting key messages
May represent department or team on program/project team or sub‑team
Basic Qualifications
Bachelors Degree (5+ years of academic and / or industry experience) Or
Masters Degree (3+ years of academic and / or industry experience) Or
Ph.D. or equivalent advanced degree in the Life Sciences (No experience necessary)
Preferred Qualifications
Experience culturing T cells including aseptic technique, T cell activation, and maintenance of primary cell cultures
Experience with multi‑color flowcytometry including complex panel design and multi‑parameter data analysis (FlowJo)
Hands‑on experience with gene editing technologies (CRISPR/Cas9 preferred)
Strong knowledge of molecular biology and prior experience with DNA design tools such as Benchling, SnapGene, etc.
Experience designing and generating libraries for pooled screens and/or developing automated screening platforms
Ability to effectively multi‑task, independently organize time, and can develop timelines and deliver results accordingly
Demonstrated ability to work within a team and thrive in a fast‑paced and ever‑changing environment
Detail oriented with excellent verbal and written communication skills and careful documentation (prior ELN experience a plus)
#J-18808-Ljbffr