Volastra Therapeutics
Scientist/Senior Scientist, Preclinical Development and Translational Science
Volastra Therapeutics, New York, New York, us, 10261
Overview
Company Volastra Therapeutics, Inc. is a clinical-stage oncology biotech company based in New York City, pioneering novel approaches to treating cancer by targeting chromosomal instability (CIN), a unique vulnerability in cancer. Since its founding in 2019, Volastra has grown to support ongoing discovery efforts and a growing clinical organization. Lead programs : Focus on two distinct inhibitors of KIF18A. VLS-1488, internally discovered, entered clinical trials in Q4 2023 for the treatment of advanced cancers. Sovilnesib, in-licensed from Amgen in 2023, re-entered the clinic in Q2 2024. Both assets have been granted Fast-Track Designation by the FDA. Location : Headquartered in West Harlem, New York City. The role is based in NYC with a minimum of 80% in-office time. For more information, visit www.volastratx.com. Job Description
The role of Scientist/Senior Scientist of Preclinical Development and Translational Science will report to the Senior Director of Translational Science and Biomarkers, and will support the successful execution of preclinical development programs and translational science investigations. The ideal candidate will have strong laboratory skills and preclinical biomarker experience, be detail-oriented and self-motivated, with highly relevant experience. The role offers opportunities to grow and gain experience beyond the direct scope of work. Job is based in NYC and requires a minimum of 80% in-office time. Responsibilities
In collaboration with the Translational Science and Discovery Science teams, design and execute experimental plans to address translational questions informing clinical development plans. Coordinate and oversee studies at contract research organizations (CROs). Develop and execute existing and/or new biomarker assays and assay strategies for biomarker application and validation. Coordinate activities and timelines with Development teams to ensure seamless biomarker capabilities support for clinical trials. Analyze, interpret, and communicate translational results with relevant team members. Assist in preparation of biomarker reports, meeting presentations, and regulatory submission documents. Qualifications
MS in a related field; PhD a plus but not required. 2+ years of industry experience in preclinical development and clinical oncology biomarker work. 5+ years of hands-on lab experience with cell-based assays, molecular biology, and histology; in vivo mouse experience preferred. Knowledge of antibody-drug conjugates (ADC) biology and broad experience with in vitro and in vivo ADC testing. Experience in development and validation of biomarker assays for clinical samples. Track record of managing external projects with CROs from scoping to final data delivery. Understanding of the drug development process from target identification to marketing authorization. Basic understanding of regulatory aspects of medical diagnostics. Excellent communication, organizational, and problem-solving skills. Salary Range
Approximately $120,000 - $180,000, depending on qualifications, experience, and leveling. Exceptional candidates may be considered for leveling outside this range on a case-by-case basis. Additional Information
We are an equal opportunity employer. Referrals increase your chances of interviewing at Volastra Therapeutics. Get notified about new Senior Scientist roles in New York, NY.
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Company Volastra Therapeutics, Inc. is a clinical-stage oncology biotech company based in New York City, pioneering novel approaches to treating cancer by targeting chromosomal instability (CIN), a unique vulnerability in cancer. Since its founding in 2019, Volastra has grown to support ongoing discovery efforts and a growing clinical organization. Lead programs : Focus on two distinct inhibitors of KIF18A. VLS-1488, internally discovered, entered clinical trials in Q4 2023 for the treatment of advanced cancers. Sovilnesib, in-licensed from Amgen in 2023, re-entered the clinic in Q2 2024. Both assets have been granted Fast-Track Designation by the FDA. Location : Headquartered in West Harlem, New York City. The role is based in NYC with a minimum of 80% in-office time. For more information, visit www.volastratx.com. Job Description
The role of Scientist/Senior Scientist of Preclinical Development and Translational Science will report to the Senior Director of Translational Science and Biomarkers, and will support the successful execution of preclinical development programs and translational science investigations. The ideal candidate will have strong laboratory skills and preclinical biomarker experience, be detail-oriented and self-motivated, with highly relevant experience. The role offers opportunities to grow and gain experience beyond the direct scope of work. Job is based in NYC and requires a minimum of 80% in-office time. Responsibilities
In collaboration with the Translational Science and Discovery Science teams, design and execute experimental plans to address translational questions informing clinical development plans. Coordinate and oversee studies at contract research organizations (CROs). Develop and execute existing and/or new biomarker assays and assay strategies for biomarker application and validation. Coordinate activities and timelines with Development teams to ensure seamless biomarker capabilities support for clinical trials. Analyze, interpret, and communicate translational results with relevant team members. Assist in preparation of biomarker reports, meeting presentations, and regulatory submission documents. Qualifications
MS in a related field; PhD a plus but not required. 2+ years of industry experience in preclinical development and clinical oncology biomarker work. 5+ years of hands-on lab experience with cell-based assays, molecular biology, and histology; in vivo mouse experience preferred. Knowledge of antibody-drug conjugates (ADC) biology and broad experience with in vitro and in vivo ADC testing. Experience in development and validation of biomarker assays for clinical samples. Track record of managing external projects with CROs from scoping to final data delivery. Understanding of the drug development process from target identification to marketing authorization. Basic understanding of regulatory aspects of medical diagnostics. Excellent communication, organizational, and problem-solving skills. Salary Range
Approximately $120,000 - $180,000, depending on qualifications, experience, and leveling. Exceptional candidates may be considered for leveling outside this range on a case-by-case basis. Additional Information
We are an equal opportunity employer. Referrals increase your chances of interviewing at Volastra Therapeutics. Get notified about new Senior Scientist roles in New York, NY.
#J-18808-Ljbffr