BioSpace
Scientist I – MSAT (Cell & Gene Therapy) (Contractor)
BioSpace, Trenton, New Jersey, United States
Overview
Legend Biotech is a global biotechnology company dedicated to treating life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies, including autologous and allogeneic CAR-T, TCR-T, and NK cell-based immunotherapies. Legend Biotech collaborates with Janssen to jointly develop and commercialize cilta-cel as part of a strategic partnership designed to advance immunotherapy for multiple myeloma. Role: Scientist I – MSAT (Cell & Gene Therapy) (Contractor)
– MSAT team based in Somerset, NJ. This is a contracted position supporting the development, troubleshooting, and optimization of automated manufacturing processes for CAR-T and other cell therapy products. Under the guidance of senior staff, this role will perform bio-pilot run experiments, technology evaluations, and process improvement studies. The position contributes to manufacturing robustness and efficiency by executing laboratory work, assisting in equipment testing, and analyzing process data. Responsibilities begin with executing bench-scale experiments, technology evaluations, and process improvements, with increasing independence under approved study protocols. Key Responsibilities
Execute bench-scale experiments for bio-pilot run comparisons, technology evaluations, and process improvement initiatives. Operate and assist in troubleshooting closed-system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G-Rex). Perform and interpret analytical assays, including flow cytometry, qPCR, ELISA, and other cell-based methods, to support process evaluation and comparability. Collect, analyze, and summarize experimental data (cell growth, viability, metabolite trends) using statistical tools. Support preparation of study protocols, technical reports, and SOPs in compliance with GMP standards. Assist in process troubleshooting and root-cause investigations for manufacturing and automation systems. Maintain a safe, organized, and compliant laboratory workspace. The role makes independent decisions regarding routine laboratory execution, minor troubleshooting, and data analysis within approved study protocols, with guidance from senior team members for experimental design and major changes to validated processes. Qualifications
Bachelor’s degree in biotechnology, bioengineering, molecular biology, or related discipline. 2–4 years’ experience in cell culture (T-cells, immune cells, or primary cells) in academic, process development, or GMP environments. Hands-on experience with aseptic technique and biosafety cabinet work. Exposure to closed-system or automated manufacturing platforms preferred (e.g., Prodigy, Rotea, Cue, Lovo). Hands-on experience with analytical assays (flow cytometry, qPCR, ELISA) in a cell therapy, immunology, or bioprocess setting. Experience in basic analytical methods such as cell counting, viability assays, and metabolite monitoring. Familiarity with data analysis and preparation of technical documentation. Proficiency with Microsoft Office (Excel, Word, PowerPoint). Basic data analysis using Excel, JMP, or similar tools. Ability to interface with instrument control software. Benefits
We are committed to creating a workplace where employees can thrive—professionally and personally. Our benefits package supports well-being, financial stability, and long-term career growth, including medical, dental, and vision insurance; a 401(k) plan with company match; equity and stock options for eligible roles; paid parental leave; and a comprehensive paid time off policy. Additional benefits include flexible spending accounts, health savings accounts, life and AD&D insurance, short- and long-term disability, legal assistance, and supplemental plans. We also offer commuter benefits, family planning resources, well-being initiatives, and peer-to-peer recognition programs. EEO Statement
Legend Biotech is an equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by applicable law. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend Biotech maintains a drug-free workplace.
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Legend Biotech is a global biotechnology company dedicated to treating life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies, including autologous and allogeneic CAR-T, TCR-T, and NK cell-based immunotherapies. Legend Biotech collaborates with Janssen to jointly develop and commercialize cilta-cel as part of a strategic partnership designed to advance immunotherapy for multiple myeloma. Role: Scientist I – MSAT (Cell & Gene Therapy) (Contractor)
– MSAT team based in Somerset, NJ. This is a contracted position supporting the development, troubleshooting, and optimization of automated manufacturing processes for CAR-T and other cell therapy products. Under the guidance of senior staff, this role will perform bio-pilot run experiments, technology evaluations, and process improvement studies. The position contributes to manufacturing robustness and efficiency by executing laboratory work, assisting in equipment testing, and analyzing process data. Responsibilities begin with executing bench-scale experiments, technology evaluations, and process improvements, with increasing independence under approved study protocols. Key Responsibilities
Execute bench-scale experiments for bio-pilot run comparisons, technology evaluations, and process improvement initiatives. Operate and assist in troubleshooting closed-system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G-Rex). Perform and interpret analytical assays, including flow cytometry, qPCR, ELISA, and other cell-based methods, to support process evaluation and comparability. Collect, analyze, and summarize experimental data (cell growth, viability, metabolite trends) using statistical tools. Support preparation of study protocols, technical reports, and SOPs in compliance with GMP standards. Assist in process troubleshooting and root-cause investigations for manufacturing and automation systems. Maintain a safe, organized, and compliant laboratory workspace. The role makes independent decisions regarding routine laboratory execution, minor troubleshooting, and data analysis within approved study protocols, with guidance from senior team members for experimental design and major changes to validated processes. Qualifications
Bachelor’s degree in biotechnology, bioengineering, molecular biology, or related discipline. 2–4 years’ experience in cell culture (T-cells, immune cells, or primary cells) in academic, process development, or GMP environments. Hands-on experience with aseptic technique and biosafety cabinet work. Exposure to closed-system or automated manufacturing platforms preferred (e.g., Prodigy, Rotea, Cue, Lovo). Hands-on experience with analytical assays (flow cytometry, qPCR, ELISA) in a cell therapy, immunology, or bioprocess setting. Experience in basic analytical methods such as cell counting, viability assays, and metabolite monitoring. Familiarity with data analysis and preparation of technical documentation. Proficiency with Microsoft Office (Excel, Word, PowerPoint). Basic data analysis using Excel, JMP, or similar tools. Ability to interface with instrument control software. Benefits
We are committed to creating a workplace where employees can thrive—professionally and personally. Our benefits package supports well-being, financial stability, and long-term career growth, including medical, dental, and vision insurance; a 401(k) plan with company match; equity and stock options for eligible roles; paid parental leave; and a comprehensive paid time off policy. Additional benefits include flexible spending accounts, health savings accounts, life and AD&D insurance, short- and long-term disability, legal assistance, and supplemental plans. We also offer commuter benefits, family planning resources, well-being initiatives, and peer-to-peer recognition programs. EEO Statement
Legend Biotech is an equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by applicable law. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend Biotech maintains a drug-free workplace.
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