Kardigan
Sr. Manager, Technical Operations Program Manager
Kardigan, South San Francisco, California, us, 94083
Sr. Manager, Technical Operations Program Manager
About Us
Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve. Led by Tassos Giannakakos, Jay Edelberg, M.D. and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020. We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients. At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals.
Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in
being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an
eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to
winning as a team
with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to
enable the impossible
because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries. These values are the foundation of our work, empowering us to make a real difference, every day.
Position Summary
Kardigan is a 4- day onsite company- M - Th
The
Senior Manager, Technical Operations Program Manager
(TOPM) will support one or more clinical-stage programs by enabling effective coordination and execution of deliverables within Technical Operations (Tech Ops). Partnering closely with Tech Ops Program Leads, this individual will provide project management support to ensure seamless execution of program plans, timely follow-up of actions and issues, and operational readiness for decision-making forums. The role is highly cross-functional, working with stakeholders across Tech Ops, CMC Quality, CMC Regulatory, and other cross-functional partners.
Key Responsibilities
Program Execution & Tracking
Support one or more development programs by maintaining integrated Tech Ops timelines and deliverables across drug substance, drug product, analytical, supply chain, and other partnering functions
Manage action and RAID (Risks, Assumptions, Issues, Decisions) logs and drive timely follow-up and closure
Proactively identify items requiring discussion or decision; support teams in developing recommendations and bring them forward to the appropriate forums
Team & Meeting Support
Partner with Tech Ops Program Leads to organize and manage program-related team meetings, ensuring effective discussions and alignment
Prepare agendas, slide decks, and meeting minutes; track and follow up on action items
Ensure seamless information cascade between Tech Ops teams, governance forums, and cross-functional partners
Coordinate preparation of clear, high-quality program updates and recommendations for Tech Ops leadership, the Global Program Team (GPT), and other forums
Cross-Functional Collaboration
Partner closely with CMC Quality, CMC Regulatory, and other stakeholders to ensure alignment on program strategy, risks, and deliverables
Facilitate communication and accountability across Tech Ops and key cross-functional teams
Process & Tool Optimization
Champion the use of Smartsheet for project tracking, RAID management, and reporting
Contribute to standardized processes and templates that enable scalability as the Tech Ops portfolio grows
Qualifications
Bachelor’s degree in life sciences, engineering, or related discipline preferred; PMP certification preferred
6+ years of relevant experience in biotechnology/pharmaceutical development, with exposure to CMC, Technical Operations, and program management
Strong understanding of late-stage development and CMC deliverables; prior NDA, BLA, or launch experience strongly preferred
Proven success managing complex, cross-functional projects with multiple stakeholders
Highly organized, detail-oriented, and adept at balancing multiple priorities in a dynamic environment
Strong interpersonal and communication skills with the ability to influence without authority
Proficiency in Microsoft Suite and Smartsheet
Key Attributes
Collaborative partner and team player with a service-oriented mindset
Strong commitment to accountability, follow-through, and delivering results
Comfortable working with agility and adapting to shifting priorities
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Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.
As set forth in Kardigan’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
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Voluntary Self-Identification of Disability Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 04/30/2026 Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp .
How do you know if you have a disability?
A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.
Disabilities include, but are not limited to:
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Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
Blind or low vision
Cancer (past or present)
Cardiovascular or heart disease
Celiac disease
Cerebral palsy
Deaf or serious difficulty hearing
Diabetes
Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
Epilepsy or other seizure disorder
Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
Intellectual or developmental disability
Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
Missing limbs or partially missing limbs
Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
Partial or complete paralysis (any cause)
Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
Short stature (dwarfism)
Traumatic brain injury
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Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve. Led by Tassos Giannakakos, Jay Edelberg, M.D. and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020. We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients. At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals.
Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in
being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an
eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to
winning as a team
with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to
enable the impossible
because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries. These values are the foundation of our work, empowering us to make a real difference, every day.
Position Summary
Kardigan is a 4- day onsite company- M - Th
The
Senior Manager, Technical Operations Program Manager
(TOPM) will support one or more clinical-stage programs by enabling effective coordination and execution of deliverables within Technical Operations (Tech Ops). Partnering closely with Tech Ops Program Leads, this individual will provide project management support to ensure seamless execution of program plans, timely follow-up of actions and issues, and operational readiness for decision-making forums. The role is highly cross-functional, working with stakeholders across Tech Ops, CMC Quality, CMC Regulatory, and other cross-functional partners.
Key Responsibilities
Program Execution & Tracking
Support one or more development programs by maintaining integrated Tech Ops timelines and deliverables across drug substance, drug product, analytical, supply chain, and other partnering functions
Manage action and RAID (Risks, Assumptions, Issues, Decisions) logs and drive timely follow-up and closure
Proactively identify items requiring discussion or decision; support teams in developing recommendations and bring them forward to the appropriate forums
Team & Meeting Support
Partner with Tech Ops Program Leads to organize and manage program-related team meetings, ensuring effective discussions and alignment
Prepare agendas, slide decks, and meeting minutes; track and follow up on action items
Ensure seamless information cascade between Tech Ops teams, governance forums, and cross-functional partners
Coordinate preparation of clear, high-quality program updates and recommendations for Tech Ops leadership, the Global Program Team (GPT), and other forums
Cross-Functional Collaboration
Partner closely with CMC Quality, CMC Regulatory, and other stakeholders to ensure alignment on program strategy, risks, and deliverables
Facilitate communication and accountability across Tech Ops and key cross-functional teams
Process & Tool Optimization
Champion the use of Smartsheet for project tracking, RAID management, and reporting
Contribute to standardized processes and templates that enable scalability as the Tech Ops portfolio grows
Qualifications
Bachelor’s degree in life sciences, engineering, or related discipline preferred; PMP certification preferred
6+ years of relevant experience in biotechnology/pharmaceutical development, with exposure to CMC, Technical Operations, and program management
Strong understanding of late-stage development and CMC deliverables; prior NDA, BLA, or launch experience strongly preferred
Proven success managing complex, cross-functional projects with multiple stakeholders
Highly organized, detail-oriented, and adept at balancing multiple priorities in a dynamic environment
Strong interpersonal and communication skills with the ability to influence without authority
Proficiency in Microsoft Suite and Smartsheet
Key Attributes
Collaborative partner and team player with a service-oriented mindset
Strong commitment to accountability, follow-through, and delivering results
Comfortable working with agility and adapting to shifting priorities
Create a Job Alert
Interested in building your career at Kardigan? Get future opportunities sent straight to your email.
Accepted file types: pdf, doc, docx, txt, rtf
Enter manually
Accepted file types: pdf, doc, docx, txt, rtf
Education
School Select...
Degree Select...
Select...
LinkedIn Profile
Will you now or in the future require sponsorship to work in the United States? * Select...
Are you willing to come into the office up to 4 days per week? (Kardigan offices located in South San Francisco, CA or Princeton, NJ) * Select...
Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.
As set forth in Kardigan’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Select...
Voluntary Self-Identification of Disability Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026
Voluntary Self-Identification of Disability Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 04/30/2026 Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp .
How do you know if you have a disability?
A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.
Disabilities include, but are not limited to:
Alcohol or other substance use disorder (not currently using drugs illegally)
Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
Blind or low vision
Cancer (past or present)
Cardiovascular or heart disease
Celiac disease
Cerebral palsy
Deaf or serious difficulty hearing
Diabetes
Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
Epilepsy or other seizure disorder
Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
Intellectual or developmental disability
Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
Missing limbs or partially missing limbs
Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
Partial or complete paralysis (any cause)
Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
Short stature (dwarfism)
Traumatic brain injury
Disability Status Select...
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
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