MSD Malaysia
Associate Scientist, Postdoctoral Fellow - Chemical Biology in Data Rich Experim
MSD Malaysia, Rahway, New Jersey, us, 07065
Associate Scientist, Postdoctoral Fellow - Chemical Biology in Data Rich Experimentation (DRE)
Be a part of Merck’s legacy through the Postdoctoral Research Fellow Program, a best‑in‑industry initiative designed to provide academic focus within a commercial environment. As a full‑time, remote‑eligible Postdoctoral Research Fellow, you will join the Data Rich Experimentation (DRE) team in the Process Research & Development Enabling Technologies (PR&D ET) organization to develop high‑throughput tools for RNA dynamics and secondary structure analysis.
Position Overview The role focuses on developing state‑of‑the‑art bioconjugation and coupled enzyme assay technologies to generate novel high‑throughput assays for RNA structure‑function relationships. Your work will support predictive model development and be shared in high‑impact, peer‑reviewed publications and external presentations.
Responsibilities
Identify fluorescence reporter systems to enable multiplexed RNA dynamic and secondary structure characterization assays.
Develop and advance experimental approaches to efficiently generate bioconjugates in a site‑specific and robust manner.
Design high‑throughput assays to build informer data sets for RNA dynamics and secondary structure predictive software.
Apply cutting‑edge chemistry techniques, including high‑throughput experimentation (HTE) and data‑rich experimentation (DRE), to solve problems, gain mechanistic insight, and drive synthetic innovations.
Collaborate with colleagues across the company and adjacent functional areas (e.g., analytical, modeling, informatics).
Comply with company data retention and lab safety procedures and complete required training.
Author, contribute to, and review external publications and presentations.
Participate in internal and external scientific symposiums, seminars, and conferences.
Education Minimum Requirement
Current Ph.D. holder or Ph.D. completed within 6 months of hire in biochemistry, biophysics, organic chemistry, chemical or biological engineering, or a closely related discipline.
Required Experience and Skills
Experience with UPLC‑MS and fluorescence spectroscopy.
Expertise in organic synthesis, biochemistry, and molecular biology techniques.
Proven research project completion evidenced by peer‑reviewed publications and presentations.
Strong attention to detail, problem‑solving, and troubleshooting skills.
Ability to design experiments independently, interpret data, and incorporate findings into new designs.
Exceptional communication and collaboration skills for cross‑functional, multidisciplinary teams.
Preferred Experience and Skills
Experience working with RNA and cell‑free systems.
Experience using Python, R, or similar for high‑throughput data analysis, modeling, and/or data mining.
Experience designing protein binding and activity assays, including use of associated instrumentation.
Salary and Benefits Expected salary range: $75,000.00 – $86,000.00.
Benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days.
Equal Employment Opportunity Merck is an Equal Employment Opportunity Employer. We provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics.
For more information about your rights, visit the U.S. Equal Opportunity Employment laws and related resources listed above.
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Position Overview The role focuses on developing state‑of‑the‑art bioconjugation and coupled enzyme assay technologies to generate novel high‑throughput assays for RNA structure‑function relationships. Your work will support predictive model development and be shared in high‑impact, peer‑reviewed publications and external presentations.
Responsibilities
Identify fluorescence reporter systems to enable multiplexed RNA dynamic and secondary structure characterization assays.
Develop and advance experimental approaches to efficiently generate bioconjugates in a site‑specific and robust manner.
Design high‑throughput assays to build informer data sets for RNA dynamics and secondary structure predictive software.
Apply cutting‑edge chemistry techniques, including high‑throughput experimentation (HTE) and data‑rich experimentation (DRE), to solve problems, gain mechanistic insight, and drive synthetic innovations.
Collaborate with colleagues across the company and adjacent functional areas (e.g., analytical, modeling, informatics).
Comply with company data retention and lab safety procedures and complete required training.
Author, contribute to, and review external publications and presentations.
Participate in internal and external scientific symposiums, seminars, and conferences.
Education Minimum Requirement
Current Ph.D. holder or Ph.D. completed within 6 months of hire in biochemistry, biophysics, organic chemistry, chemical or biological engineering, or a closely related discipline.
Required Experience and Skills
Experience with UPLC‑MS and fluorescence spectroscopy.
Expertise in organic synthesis, biochemistry, and molecular biology techniques.
Proven research project completion evidenced by peer‑reviewed publications and presentations.
Strong attention to detail, problem‑solving, and troubleshooting skills.
Ability to design experiments independently, interpret data, and incorporate findings into new designs.
Exceptional communication and collaboration skills for cross‑functional, multidisciplinary teams.
Preferred Experience and Skills
Experience working with RNA and cell‑free systems.
Experience using Python, R, or similar for high‑throughput data analysis, modeling, and/or data mining.
Experience designing protein binding and activity assays, including use of associated instrumentation.
Salary and Benefits Expected salary range: $75,000.00 – $86,000.00.
Benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days.
Equal Employment Opportunity Merck is an Equal Employment Opportunity Employer. We provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics.
For more information about your rights, visit the U.S. Equal Opportunity Employment laws and related resources listed above.
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