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EPM Scientific

Machine Learning Researcher

EPM Scientific, San Francisco, California, United States, 94199

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Machine Learning Researcher – Generative Modeling for Drug Discovery A talent-dense AI4Biology team is applying frontier-scale AI to model biological systems and accelerate therapeutic development. They are building novel architectures and generative frameworks to reason about molecular behavior, predict drug toxicity and potency, and simulate complex biological interactions.

This role is suited for a thoughtful and curious scientist with deep engineering rigor, focused on designing and training models that understand and generate molecular structure, dynamics, and function. It’s a zero-to-one opportunity to shape the technical foundation of a company working at the intersection of AI and human health.

Focus Areas

Designing generative models (e.g. diffusion, flow matching, graph-based) for molecular structure and dynamics

Building predictive systems for ADMET properties, drug-likeness, and off‑target effects

Developing simulation‑informed architectures that integrate molecular dynamics and physical priors

Engineering scalable training pipelines across multi‑cloud and distributed infra

Collaborating with domain experts in chemistry, biology, and pharmacology to ground models in real‑world constraints

Prototyping and evaluating novel architectures for reasoning over multimodal biological data

Ideal Background

Experience building or publishing on generative models for molecules, proteins, or materials

Familiarity with molecular dynamics simulations or physics‑informed ML

Expertise in graph neural networks, transformers, or diffusion models

Track record of shipping ML systems in production or research environments

Interest in model interpretability, uncertainty, and scientific grounding

Comfort working across disciplines and translating abstract scientific goals into concrete ML systems

Bonus

Experience with ADMET modeling, QSAR, or cheminformatics

Familiarity with simulation engines (e.g. OpenMM, GROMACS) or quantum chemistry tools

Contributions to open‑source ML or scientific computing projects

Candidates from

any

biological or scientific background are encouraged to apply. No specific domain (e.g., ADMET, chemistry, etc.) is required. Intellectual honesty, engineering excellence, and scientific curiosity are valued above domain specialization.

Seniority level

Mid‑Senior level

Employment type

Full‑time

Job function

Research and Science

Industries

Research Services

Biotechnology Research

Pharmaceutical Manufacturing

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