Zs Associates
Manager – Manufacturing Digital Twin
Zs Associates, South San Francisco, California, us, 94083
MANAGER - MANUFACTURING DIGITAL TWIN
ZS is a place where passion changes lives. As a management consulting and technology firm focused on improving life and how we live it, we transform ideas into impact by bringing together data, science, technology and human ingenuity to deliver better outcomes for all. Here you’ll work side‑by‑side with a powerful collective of thinkers and experts shaping life‑changing solutions for patients, caregivers and consumers, worldwide. ZSers drive impact by bringing a client‑first mentality to each and every engagement. We partner collaboratively with our clients to develop custom solutions and technology products that create value and deliver company results across critical areas of their business. Bring your curiosity for learning, bold ideas, courage and passion to drive life‑changing impact to ZS.
ZS’s Supply Chain & Manufacturing group helps our clients to drive higher product availability at lower costs and lower environmental impact through leveraging analytics, automation and process re‑design approaches. Our offerings span the spectrum of strategy, advanced analytics, planning and technology to optimize deployment of resources while maintaining customer service levels.
What You’ll Do Simulation & Digital Twin Delivery
Architect and implement simulation‑first digital twin frameworks that integrate real‑time data, process models, and 3D environments to mirror and optimize physical manufacturing systems.
Lead cross‑functional teams to model, simulate, and validate workflows, enabling clients to test scenarios, reduce downtime, and improve throughput before deploying changes in the real world.
Apply knowledge of physics‑based modeling, robotics simulation, virtual commissioning, and advanced analytics to support clients in achieving smarter, faster factory performance.
Client Leadership & Transformation Strategy
Serve as a trusted advisor for senior manufacturing and digital leaders, helping them identify where and how to deploy digital twin technologies for maximum impact.
Shape strategic roadmaps for digital twin adoption—including capability assessments, maturity models, and value realization frameworks.
Guide clients through technology selection, system integration, and change management efforts aligned with simulation‑led innovation.
Innovation & Asset Development
Advance ZS’s digital twin offerings by building reusable simulation assets, technical POVs, and cross‑industry playbooks.
Stay at the forefront of simulation technology trends (e.g., NVIDIA Omniverse, OpenUSD, PLM/CAD connectors) and contribute to thought leadership.
Team Development & Collaboration
Lead and mentor global teams of simulation engineers, process modelers, and digital solution architects.
Collaborate with stakeholders across engineering, IT, and operations to ensure successful integration of digital and physical ecosystems.
What You’ll Bring Education & Experience
Bachelor’s degree in Engineering, Computer Science, Mechatronics, or a related technical field; Master’s or MBA strongly preferred.
Minimum 7+ years’ experience in manufacturing operations, simulation, digital engineering, or digital twin implementations.
Technical Expertise
Proven experience with manufacturing simulation tools such as Siemens Tecnomatix, Dassault DELMIA, or similar platforms.
Deep knowledge of robotics simulation, factory automation, and virtual commissioning practices.
Familiarity with NVIDIA Omniverse (USD Composer/View, Nucleus Server), OpenUSD standards, and CAD/PLM tools (NX, Revit, SolidWorks).
Understanding of live data integration with MES, SCADA, and ERP systems to enable real‑time overlays in digital twins.
Leadership & Communication
Strong analytical, consultative, and problem‑solving capabilities with the ability to articulate technical concepts to business audiences.
Experience managing multi‑disciplinary teams across geographies and projects.
Excellent verbal and written communication skills, with the ability to influence stakeholders and drive decisions.
Nice to Have
Experience in regulated industries (biopharma, medtech), with understanding of GxP compliance, 21 CFR Part 11, EU Annex 11.
Prior consulting or client‑facing experience with complex digital transformation initiatives.
Why Join Us? At ZS, you will help reimagine the future of manufacturing—driving simulation‑led innovation that transforms physical processes into digital opportunities. This is a unique opportunity to shape industry‑leading digital twin strategies that deliver real business impact.
Hybrid working model ZS is committed to a flexible and connected way of working. ZSers are onsite at clients or ZS offices three days a week. Combined flexibility to work remotely two days a week is also available. The magic of ZS culture and innovation thrives in both planned and spontaneous face‑to‑face connections.
Perks & Benefits ZS offers a comprehensive total rewards package including health and well‑being, financial planning, annual leave, personal growth and professional development. Our robust skills development programs, multiple career progression options and internal mobility paths and collaborative culture empower you to thrive as an individual and global team member.
Travel Travel is a requirement at ZS for client‑facing ZSers; business needs of your project and client are the priority. While some projects may be local, all client‑facing ZSers should be prepared to travel as needed. Travel provides opportunities to strengthen client relationships, gain diverse experiences, and enhance professional growth by working in different environments and cultures.
Considering applying? At ZS, we honor the visible and invisible elements of our identities, personal experiences, and belief systems—the ones that comprise us as individuals, shape who we are, and make us unique. We believe your personal interests, identities, and desire to learn are integral to your success here. We are committed to building a team that reflects a broad variety of backgrounds, perspectives, and experiences. Learn more about our inclusion and belonging efforts and the networks ZS supports to assist our ZSers in cultivating community spaces and obtaining the resources they need to thrive.
If you’re eager to grow, contribute, and bring your unique self to our work, we encourage you to apply.
ZS is an equal opportunity employer and is committed to providing equal employment and advancement opportunities without regard to any class protected by applicable law.
Candidates must possess or be able to obtain work authorization for their intended country of employment. An online application, including a full set of transcripts (official or unofficial), is required to be considered.
NO AGENCY CALLS, PLEASE.
Find Out More At: www.zs.com
#J-18808-Ljbffr
ZS’s Supply Chain & Manufacturing group helps our clients to drive higher product availability at lower costs and lower environmental impact through leveraging analytics, automation and process re‑design approaches. Our offerings span the spectrum of strategy, advanced analytics, planning and technology to optimize deployment of resources while maintaining customer service levels.
What You’ll Do Simulation & Digital Twin Delivery
Architect and implement simulation‑first digital twin frameworks that integrate real‑time data, process models, and 3D environments to mirror and optimize physical manufacturing systems.
Lead cross‑functional teams to model, simulate, and validate workflows, enabling clients to test scenarios, reduce downtime, and improve throughput before deploying changes in the real world.
Apply knowledge of physics‑based modeling, robotics simulation, virtual commissioning, and advanced analytics to support clients in achieving smarter, faster factory performance.
Client Leadership & Transformation Strategy
Serve as a trusted advisor for senior manufacturing and digital leaders, helping them identify where and how to deploy digital twin technologies for maximum impact.
Shape strategic roadmaps for digital twin adoption—including capability assessments, maturity models, and value realization frameworks.
Guide clients through technology selection, system integration, and change management efforts aligned with simulation‑led innovation.
Innovation & Asset Development
Advance ZS’s digital twin offerings by building reusable simulation assets, technical POVs, and cross‑industry playbooks.
Stay at the forefront of simulation technology trends (e.g., NVIDIA Omniverse, OpenUSD, PLM/CAD connectors) and contribute to thought leadership.
Team Development & Collaboration
Lead and mentor global teams of simulation engineers, process modelers, and digital solution architects.
Collaborate with stakeholders across engineering, IT, and operations to ensure successful integration of digital and physical ecosystems.
What You’ll Bring Education & Experience
Bachelor’s degree in Engineering, Computer Science, Mechatronics, or a related technical field; Master’s or MBA strongly preferred.
Minimum 7+ years’ experience in manufacturing operations, simulation, digital engineering, or digital twin implementations.
Technical Expertise
Proven experience with manufacturing simulation tools such as Siemens Tecnomatix, Dassault DELMIA, or similar platforms.
Deep knowledge of robotics simulation, factory automation, and virtual commissioning practices.
Familiarity with NVIDIA Omniverse (USD Composer/View, Nucleus Server), OpenUSD standards, and CAD/PLM tools (NX, Revit, SolidWorks).
Understanding of live data integration with MES, SCADA, and ERP systems to enable real‑time overlays in digital twins.
Leadership & Communication
Strong analytical, consultative, and problem‑solving capabilities with the ability to articulate technical concepts to business audiences.
Experience managing multi‑disciplinary teams across geographies and projects.
Excellent verbal and written communication skills, with the ability to influence stakeholders and drive decisions.
Nice to Have
Experience in regulated industries (biopharma, medtech), with understanding of GxP compliance, 21 CFR Part 11, EU Annex 11.
Prior consulting or client‑facing experience with complex digital transformation initiatives.
Why Join Us? At ZS, you will help reimagine the future of manufacturing—driving simulation‑led innovation that transforms physical processes into digital opportunities. This is a unique opportunity to shape industry‑leading digital twin strategies that deliver real business impact.
Hybrid working model ZS is committed to a flexible and connected way of working. ZSers are onsite at clients or ZS offices three days a week. Combined flexibility to work remotely two days a week is also available. The magic of ZS culture and innovation thrives in both planned and spontaneous face‑to‑face connections.
Perks & Benefits ZS offers a comprehensive total rewards package including health and well‑being, financial planning, annual leave, personal growth and professional development. Our robust skills development programs, multiple career progression options and internal mobility paths and collaborative culture empower you to thrive as an individual and global team member.
Travel Travel is a requirement at ZS for client‑facing ZSers; business needs of your project and client are the priority. While some projects may be local, all client‑facing ZSers should be prepared to travel as needed. Travel provides opportunities to strengthen client relationships, gain diverse experiences, and enhance professional growth by working in different environments and cultures.
Considering applying? At ZS, we honor the visible and invisible elements of our identities, personal experiences, and belief systems—the ones that comprise us as individuals, shape who we are, and make us unique. We believe your personal interests, identities, and desire to learn are integral to your success here. We are committed to building a team that reflects a broad variety of backgrounds, perspectives, and experiences. Learn more about our inclusion and belonging efforts and the networks ZS supports to assist our ZSers in cultivating community spaces and obtaining the resources they need to thrive.
If you’re eager to grow, contribute, and bring your unique self to our work, we encourage you to apply.
ZS is an equal opportunity employer and is committed to providing equal employment and advancement opportunities without regard to any class protected by applicable law.
Candidates must possess or be able to obtain work authorization for their intended country of employment. An online application, including a full set of transcripts (official or unofficial), is required to be considered.
NO AGENCY CALLS, PLEASE.
Find Out More At: www.zs.com
#J-18808-Ljbffr