Women In Bio
Scientist, Physico-Chem Analytics (Mass Spectrometry)
Women In Bio, Cambridge, Massachusetts, us, 02140
Scientist, Physico-Chemical Characterization (Mass Spectrometry)
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
To support this mission, GSK’s Greater Boston area is a key hub for biotech and pharma, with a growing R&D footprint in Cambridge. In Cambridge, we are building state‑of‑the‑art labs to develop methods that support deep product understanding and advance mRNA‑based vaccine discovery.
As a Scientist, you will perform analytical development alongside scientists and principal scientists to support early‑stage product understanding in a variety of vaccine platforms, with a focus on mRNA, mRNA‑LNP, and protein characterization methodologies, building on your expertise in mass spectrometric techniques.
Key Responsibilities
Develop LC‑MS and LC‑MS/MS methods to characterize mRNA, DNA, proteins, N‑glycans, lipids, and vaccine components.
Perform routine biophysical characterization methods such as LC‑MS, LC‑MS/MS, UHPLC, CGE, light scattering, particle characterization, spectroscopy, calorimetry, and compendial tests as needed.
Prepare samples for characterization studies.
Maintain thorough electronic lab notebooks and documentation records.
Deliver reproducible and impactful results under ambitious timelines.
Execute and troubleshoot standard protocols, develop and adapt new protocols into practice to improve assays.
Participate actively in a high‑performing team of top scientists driven by innovation, quality, and excellence.
Cultivate department culture: excellence in science and operations, fostering a positive culture of transparency and collaboration within the global organization.
Develop next‑generation analytical methods for next‑generation mRNA vaccines using innovative physicochemical/separation technologies and automation in collaboration with Preclinical, Drug Substance (DS), and Drug Product (DP) teams.
Basic Qualifications
MS or PhD in Chemistry, Biology, Biochemistry, Biotechnology, Bioengineering, Chemical Engineering, or a related scientific field.
MS candidates should have three or more years of additional laboratory experience.
PhD with no additional laboratory experience is acceptable.
Two or more years of experience in mass spectrometry‑based technologies of biomolecules (mRNA, DNA, or Proteins).
Preferred Qualifications
mRNA‑LNP vaccine analytics or vaccine development experience.
Strong theoretical and practical background in proteomics and biophysical characterization methodologies.
A good understanding of biopharma/vaccine development process.
Proven ability to work effectively within cross‑functional and multidisciplinary teams to combine analytical technologies.
Strong verbal and written communication skills; good presentation skills.
Capacity to synthesize messages and defend scientific and technical decisions in constructive interactions.
Ability to work with cross‑functional teams.
Adaptable team player with a passion to learn.
Positive, open, and can‑do mindset.
Driven by excellence, creativity, accountability, and flexibility in a collaborative and innovative environment.
Critical thinker with strong problem‑solving skills, capable of synthesizing key messages and supporting constructive interactions and decision‑making.
Fluency in English.
The annual base salary for new hires in this position ranges from $89,100 to $148,500, depending on location, skills, experience, education level, and market rates. The role also includes an annual bonus and eligibility to participate in our share‑based long‑term incentive program. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
Please learn more about the comprehensive benefits program GSK offers US employees on our GSK US Benefits Summary.
Why GSK? GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade through innovation in specialty medicines and vaccines. Our culture is built on ambition for patients, accountability for impact, and doing the right thing.
Equal Opportunity Employer GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. In the absence of such written authorization, any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
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At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
To support this mission, GSK’s Greater Boston area is a key hub for biotech and pharma, with a growing R&D footprint in Cambridge. In Cambridge, we are building state‑of‑the‑art labs to develop methods that support deep product understanding and advance mRNA‑based vaccine discovery.
As a Scientist, you will perform analytical development alongside scientists and principal scientists to support early‑stage product understanding in a variety of vaccine platforms, with a focus on mRNA, mRNA‑LNP, and protein characterization methodologies, building on your expertise in mass spectrometric techniques.
Key Responsibilities
Develop LC‑MS and LC‑MS/MS methods to characterize mRNA, DNA, proteins, N‑glycans, lipids, and vaccine components.
Perform routine biophysical characterization methods such as LC‑MS, LC‑MS/MS, UHPLC, CGE, light scattering, particle characterization, spectroscopy, calorimetry, and compendial tests as needed.
Prepare samples for characterization studies.
Maintain thorough electronic lab notebooks and documentation records.
Deliver reproducible and impactful results under ambitious timelines.
Execute and troubleshoot standard protocols, develop and adapt new protocols into practice to improve assays.
Participate actively in a high‑performing team of top scientists driven by innovation, quality, and excellence.
Cultivate department culture: excellence in science and operations, fostering a positive culture of transparency and collaboration within the global organization.
Develop next‑generation analytical methods for next‑generation mRNA vaccines using innovative physicochemical/separation technologies and automation in collaboration with Preclinical, Drug Substance (DS), and Drug Product (DP) teams.
Basic Qualifications
MS or PhD in Chemistry, Biology, Biochemistry, Biotechnology, Bioengineering, Chemical Engineering, or a related scientific field.
MS candidates should have three or more years of additional laboratory experience.
PhD with no additional laboratory experience is acceptable.
Two or more years of experience in mass spectrometry‑based technologies of biomolecules (mRNA, DNA, or Proteins).
Preferred Qualifications
mRNA‑LNP vaccine analytics or vaccine development experience.
Strong theoretical and practical background in proteomics and biophysical characterization methodologies.
A good understanding of biopharma/vaccine development process.
Proven ability to work effectively within cross‑functional and multidisciplinary teams to combine analytical technologies.
Strong verbal and written communication skills; good presentation skills.
Capacity to synthesize messages and defend scientific and technical decisions in constructive interactions.
Ability to work with cross‑functional teams.
Adaptable team player with a passion to learn.
Positive, open, and can‑do mindset.
Driven by excellence, creativity, accountability, and flexibility in a collaborative and innovative environment.
Critical thinker with strong problem‑solving skills, capable of synthesizing key messages and supporting constructive interactions and decision‑making.
Fluency in English.
The annual base salary for new hires in this position ranges from $89,100 to $148,500, depending on location, skills, experience, education level, and market rates. The role also includes an annual bonus and eligibility to participate in our share‑based long‑term incentive program. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
Please learn more about the comprehensive benefits program GSK offers US employees on our GSK US Benefits Summary.
Why GSK? GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade through innovation in specialty medicines and vaccines. Our culture is built on ambition for patients, accountability for impact, and doing the right thing.
Equal Opportunity Employer GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. In the absence of such written authorization, any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
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