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Washington University in St. Louis

Postdoctoral Research Associate (Proteomics and Multi-omics in Neurodegeneration

Washington University in St. Louis, Northfield, Vermont, us, 05663

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The Cruchaga lab at WashU Medicine is recruiting multiple Postdoctoral Research Associates. The Cruchaga lab generates and analyzes high-throughput multi-omic data to study neurodegeneration and diseases of the central nervous system with emphasis on Alzheimer’s disease, Parkinson’s disease, and other dementias. The ultimate goal of the lab is to understand the biology of these diseases, to define novel biomarkers, and to identify novel therapeutical targets. We have pioneered in the integration of genetics with omic data to identify proteomic signatures and develop novel predictive models for Alzheimer’s, Parkinson, and Dystonia as well as to identify novel proteins and pathways implicated on disease pathogenesis. We are currently analyzing brain, CSF and blood, multi-omic data (transcriptomics, proteomics and metabolomics), from a large collection of well-characterized samples to identify novel biomarker and causal and druggable targets. We are seeking a motivated researcher with strong analytical skills to join our effort and generate novel insights of neurodegeneration with this unique dataset, while working in a highly dynamic multidisciplinary and collaborative environment. Job Description

Primary Duties & Responsibilities: For more information on being a postdoc at Washington University in St. Louis, please visit

https://postdoc.wustl.edu/prospective-postdocs-2/ . Working Conditions: This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals. Salary Range: Base pay is commensurate with experience. Required Qualifications

Education: Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree. Skills: The successful applicant will hold, or shortly expects to obtain, a PhD qualification in Genetics, Bioinformatics, Computer science, Data science, Statistical Genomics or a related discipline involving the interrogation of ‘omics’ datasets. Hands-on experience with large-scale human omics (preferably related to neurodegeneration) studies is expected. Preferred Qualifications

Skilled in at least one programming language (R, Python or Perl) and experience working in Linux and/or high-performance cluster environments. A strong ability to perform analytical reasoning to extract biological insights from data-driven approaches will be critical. In addition, familiarity to interrogate publicly available resources will be highly beneficial. EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

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