UC San Diego
Lab Assistant II
Filing Deadline: Thu 11/13/2025
Location: La Jolla, 9500 Gilman Drive, San Diego, CA 92093, United States
UCSG Layoff and Special Selection Notice UCSD Layoff from Career Appointment: Apply by 11/4/2025 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 11/13/2025. Eligible Special Selection clients should contact their Disability Counselor for assistance.
DESCRIPTION The Department of Neurosciences is a leading clinical‑academic department within the UCSD School of Medicine, comprised of more than 130 faculty members. The department’s mission is to create synergies and define ideas and programs that transform how the neurosciences community discovers, teaches, and cares for patients. We conduct cutting‑edge science and research and train the next generation of neurologists and researchers by fostering education at all levels and integrating the latest scientific and medical advances into the curriculum.
Under the direct supervision of the Principal Investigator (PI) and the lab manager, the incumbent will serve as a Lab Assistant in a cutting‑edge Neurosciences laboratory dedicated to modeling human brain aging and neurodegenerative diseases. The research focuses on metabolic regulation and early mild cognitive impairment relevant to Alzheimer’s disease and related disorders. Responsibilities include executing advanced human neural cell reprogramming techniques to generate induced neuronal cultures that model brain aging and neurodegeneration, developing and optimizing novel culture systems employing innovative biomaterials, and applying state‑of‑the‑art genetic research methodologies. The role also involves confocal microscopy imaging, molecular biology assays, and generating and analyzing metabolic datasets to elucidate cellular phenotypes associated with neuronal vulnerability and cognitive decline. In addition to experimental duties, the assistant will perform limited laboratory management tasks such as inventory maintenance, sample organization, and aliquoting, and collaborate closely with interdisciplinary team members to ensure seamless integration of experimental workflows aligned with project goals in neurodegenerative disease modeling and therapeutic discovery. Perform other duties as assigned.
MINIMUM QUALIFICATIONS
Theoretical and practical background in molecular biology combined with bachelor’s‑level coursework in biology or related science with laboratory experience.
Ability to follow basic research protocols and instructions closely.
Ability to perform a limited variety of non‑standard experimental procedures involving human cell culture and reprogramming experiments, and various molecular approaches with accuracy and attention to detail. Willingness and ability to learn new techniques and tasks.
Ability to effectively communicate with colleagues and superiors, with demonstrated skill in asking questions and advising of problems, via effective use of email, shared documents, and meeting schedules.
Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.
Strong theoretical background in application of human neural cell culture models in biomedical sciences, and strong practical experience with human neural reprogramming, confocal imaging, and molecular assays such as qPCR. Experience with data analysis and software applications such as Word, Prism, and Excel.
Knowledge of medical and scientific terminology and familiarity with those associated with cellular neurobiology.
Ability to perform accurate record keeping and organize and calculate data. Skill to plan and organize work assignments efficiently.
SPECIAL CONDITIONS
Willingness to work evenings and weekends, if necessary.
Must be willing to work flexible schedule in order to complete experiments as necessary.
Must be willing to work with hazardous materials.
Pay Transparency Act Annual Full Pay Range: $48,295 - $56,794 (will be prorated if the appointment percentage is less than 100%)
Hourly Equivalent: $23.13 - $27.20
Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).
EEO / Legal Statements The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
For the University of California’s Anti-Discrimination Policy, please visit: https://policy.ucop.edu/doc/1001004/Anti-Discrimination
UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.
UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.
#J-18808-Ljbffr
Location: La Jolla, 9500 Gilman Drive, San Diego, CA 92093, United States
UCSG Layoff and Special Selection Notice UCSD Layoff from Career Appointment: Apply by 11/4/2025 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 11/13/2025. Eligible Special Selection clients should contact their Disability Counselor for assistance.
DESCRIPTION The Department of Neurosciences is a leading clinical‑academic department within the UCSD School of Medicine, comprised of more than 130 faculty members. The department’s mission is to create synergies and define ideas and programs that transform how the neurosciences community discovers, teaches, and cares for patients. We conduct cutting‑edge science and research and train the next generation of neurologists and researchers by fostering education at all levels and integrating the latest scientific and medical advances into the curriculum.
Under the direct supervision of the Principal Investigator (PI) and the lab manager, the incumbent will serve as a Lab Assistant in a cutting‑edge Neurosciences laboratory dedicated to modeling human brain aging and neurodegenerative diseases. The research focuses on metabolic regulation and early mild cognitive impairment relevant to Alzheimer’s disease and related disorders. Responsibilities include executing advanced human neural cell reprogramming techniques to generate induced neuronal cultures that model brain aging and neurodegeneration, developing and optimizing novel culture systems employing innovative biomaterials, and applying state‑of‑the‑art genetic research methodologies. The role also involves confocal microscopy imaging, molecular biology assays, and generating and analyzing metabolic datasets to elucidate cellular phenotypes associated with neuronal vulnerability and cognitive decline. In addition to experimental duties, the assistant will perform limited laboratory management tasks such as inventory maintenance, sample organization, and aliquoting, and collaborate closely with interdisciplinary team members to ensure seamless integration of experimental workflows aligned with project goals in neurodegenerative disease modeling and therapeutic discovery. Perform other duties as assigned.
MINIMUM QUALIFICATIONS
Theoretical and practical background in molecular biology combined with bachelor’s‑level coursework in biology or related science with laboratory experience.
Ability to follow basic research protocols and instructions closely.
Ability to perform a limited variety of non‑standard experimental procedures involving human cell culture and reprogramming experiments, and various molecular approaches with accuracy and attention to detail. Willingness and ability to learn new techniques and tasks.
Ability to effectively communicate with colleagues and superiors, with demonstrated skill in asking questions and advising of problems, via effective use of email, shared documents, and meeting schedules.
Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.
Strong theoretical background in application of human neural cell culture models in biomedical sciences, and strong practical experience with human neural reprogramming, confocal imaging, and molecular assays such as qPCR. Experience with data analysis and software applications such as Word, Prism, and Excel.
Knowledge of medical and scientific terminology and familiarity with those associated with cellular neurobiology.
Ability to perform accurate record keeping and organize and calculate data. Skill to plan and organize work assignments efficiently.
SPECIAL CONDITIONS
Willingness to work evenings and weekends, if necessary.
Must be willing to work flexible schedule in order to complete experiments as necessary.
Must be willing to work with hazardous materials.
Pay Transparency Act Annual Full Pay Range: $48,295 - $56,794 (will be prorated if the appointment percentage is less than 100%)
Hourly Equivalent: $23.13 - $27.20
Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).
EEO / Legal Statements The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
For the University of California’s Anti-Discrimination Policy, please visit: https://policy.ucop.edu/doc/1001004/Anti-Discrimination
UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.
UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.
#J-18808-Ljbffr