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Lunar Biosciences

Senior Staff/Principal Scientist, Organic Chemistry & Biochemistry

Lunar Biosciences, Pleasanton, California, United States, 94566

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About Lunar Biosciences:

Lunar Biosciences is a cutting‑edge biotech startup at the forefront of proteomics innovation. Headquartered in Pleasanton, California, our mission is to unlock the secrets of proteoforms through our revolutionary proteomics platform. Our technology is reshaping the landscape of drug discovery and biomarker development, driving the shift from traditional methods to precision, data‑driven medicine.

Job Description We are seeking a talented and passionate Senior Staff/Principal Scientist to join our growing team. You will lead chemistry efforts to develop multi‑step chemical processes that will be implemented in our groundbreaking technology. As part of a fast‑paced and collaborative startup environment, you will work closely with a multidisciplinary team to build core chemistry solutions for our sequencing technology.

Key Responsibilities

Contribute as a full‑time bench scientist and a leader of the chemistry team

Design, implement, and adjust strategies & R&D plans in developing chemistries for a non‑mass spec‑based proprietary proteomics workflow

Develop, verify, optimize protocols to accommodate cross‑functional processes including automation

Manage and prioritize multiple timelines across diverse projects/goals in coordination with other functional progress

Communicate the overall chemistry strategy and rationale to external parties

Proactively seek innovation – build and expand a technology pipeline & IP portfolio

Actively identify, build, and secure internal and external resources to support R&D work

Create and maintain a scientific advisory group to support R&D work

Participate in multidisciplinary team activities, commit to rapid identification and resolution of problems, and advance projects through critical internal review processes

Review research papers and intellectual property literature in support of ongoing research projects

Qualifications

Ph.D. in organic chemistry, biochemistry, medicinal chemistry, or chemical engineering with at least 10 years of professional experience in a biotech or pharma environment.

A thought leader in protein and nucleic acid chemistry.

Extensive experience in developing novel chemical methodologies for proximity ligation, surface/beads chemistry, assay development, protein (orthogonal) conjugation, proteomics sample preparation, post‑translational modifications, solid‑phase synthesis, and advanced purification techniques.

Deep understanding of Edman degradation in protein sequencing chemistry.

Good relationship with commercial resources providing services of analytical analysis of both small molecules and macromolecules.

Strong problem‑solving skills and the ability to work both independently and within a team.

Excellent people skills and presentation skills.

Willing and capable of being hands‑on in the wet‑lab.

Benefits & Compensation

Base salary: $175,000/year – $200,000/year. Final salary determined by candidate’s experience, qualifications, and skill set.

Eligible employees may receive company equity as part of the total compensation package.

Financial security through competitive compensation, incentives, and a retirement plan.

Health care and well‑being programs, including competitive medical, dental, vision, life and long‑term disability insurance.

Generous paid time off including vacation, sick time, and holidays.

401(k) retirement savings with a company match.

We continue to optimize our benefits & wellness programs as we grow to meet the diverse workforce needs.

How to Apply If you’re excited about joining a team that’s driving revolutionary change in proteomics and precision medicine, we’d love to hear from you. Apply today!

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