BridgeBio Pharma
VP, Supply Chain San Francisco, CA/Hybrid
BridgeBio Pharma, San Francisco, California, United States, 94199
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement…read on
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early‑stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life‑changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries and empower people to solve problems. If you’re someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we’ll ask “why not?” and help reengineer the future of biopharma.
Affiliate Overview Eidos Therapeutics, an affiliate within BridgeBio Pharma, is a commercial‑stage biopharmaceutical company focused on Transthyretin Amyloid Cardiomyopathy (ATTR‑CM).
What You’ll Do The Vice President of Global Supply Chain will be responsible for global end‑to‑end clinical supply chain activities related to managing supply of Investigational Product (IP) including packaging, labeling, distribution and demand forecasting for multiple clinical studies through all stages of clinical development. The role will also have responsibility for global end‑to‑end commercial supply chain activities, including the management of S&OP, Supply planning, Supplier (CMO, CPO, 3PL) management, inventory management, and partnership with Global Trade for Finished Good distribution. The role will partner closely with CMC/Manufacturing, Commercial, Clinical, and Quality Assurance teams and partner stakeholders to ensure timely and uninterrupted supply of clinical and commercial product. The individual must have the ability to manage global teams, experience in GxP industry, be an effective leader, and work efficiently in a fast‑paced environment.
Responsibilities
Manage a global team of supply chain professionals, responsible for both clinical and commercial end‑to‑end supply chain
Manage all aspects of commercial supply chain, including Drug Substance and Drug Product Contract Manufacturing Organizations (CMOs), Packaging and Labeling activities with Contract Packaging organizations (CPOs), Finished Good receiving, put away, storage and distribution activities at Third Part Logistics Providers (3PLs)
Coordinate logistics of material transfer for clinical and commercial drug substance, drug product and components to/from international CMOs/CPOs, managing exportation, applicable USDA/FDA licenses and permits, VAT recovery and customs brokers
Own the global Sales & Operations Planning (S&OP) process for all commercial products, coordinating with global market access team for demand planning, finance team for financial planning and driving ownership of final supply plan to be communicated to global partners
Own and actively manage the commercial supply plan, all commercial inventory, both in process and finished goods; manage shelf life and expiration
Own and manage all serialization activities for commercial products globally
Manage clinical packaging and labeling activities including label design, translation, production, distribution and inventory management
Provide clinical demand signals, translate the total demand into a demand forecast over time based on a clinical protocol or study overview
Prepare a clinical supply plan to support the demand, including determination of supply overage amounts, monitor inventory and provide regular inventory update to project teams
Monitor clinical drug expiry/retest dating; initiate inventory release and re‑supply, serving as the unblinded inventory manager
Manage domestic and international distribution and logistics for clinical programs, including importing and exporting clinical supplies and developing distribution instructions with clinical supply vendors
Support budget activities, including managing supplier contracts, PO generation and invoicing approvals for clinical and commercial purchases
Work collaboratively with QA to manage supply chain activities such as batch release, final release, temperature excursions and to support the investigation of any deviations in a timely manner
Work with CMC as a liaison to clinical operations and also on the evaluation of new CMOs or CPOs for commercial supply chain
Work with Global Trade & Distribution and global Finance teams to manage global 3PLs, ensuring quality Finished Good inventory management, distribution and logistics, sales and revenue reporting
Generate and maintain global SOPs in Veeva QMS and ensure updates and compliance with industry standards
Develop and maintain strong internal cross‑functional collaboration with stakeholders, such as CMC, Clinical Operations, Market Access, Finance, Quality, and Regulatory Affairs
Where You’ll Work This is a hybrid role and requires in‑office collaboration 2‑3x per week in our San Francisco Office.
Who You Are
At least fifteen (15) years of experience in Supply Chain Management and/or Manufacturing functions in the pharmaceutical and/or biotechnology industries. Title based on experience
Bachelor’s or Master’s Degree in a scientific discipline
Detailed understanding of the pharmaceutical business, including both clinical development and manufacturing and commercial manufacturing and supply chain
Proven experience with forecasting, demand/supply planning, inventory management, packaging, labeling and distribution including cold chain, import/export and reverse logistics
Proven experience managing and developing a team of professionals
Experience with SAP or similar ERP platform
Experience with product serialization, TraceLink or other similar platform and DSCSA standards
Experience with Veeva, or other similar QMS platform
Experience with clinical blinding practices
Experience in assisting set‑up of IRT systems for global clinical studies
Demonstrated skills in project management and vendor management
Working knowledge of drug development process (Phase I‑IV)
Working knowledge of current GMP/GCP/GDP guidance and regulations
Familiar with US and EU import/export regulations
Excellent attention to detail, strong data analysis, problem solving and decision‑making ability all while working in a fast‑paced and dynamic environment
Proven ability to effectively develop, communicate, and gain support for execution plans with a wide range of stakeholders
Ability to handle multiple projects simultaneously
APICS certification or supply chain education preferred
Other Information:
Position may require occasional evening and/or weekend commitment
Position may require occasional travel (up to 20%), domestic and international
Salary is competitive and commensurate with experience and qualifications
Rewarding Those Who Make the Mission Possible We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
Market leading compensation
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Referral program with $2,500 award for hired referrals
Comprehensive health care with 100% premiums covered – no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model – employees have the autonomy in where and how they do their work
Unlimited flexible paid time off – take the time that you need
Paid parental leave – 4 months for birthing parents & 2 months for non‑birthing parents
Flex spending accounts & company‑provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
Skill Development & Career Paths:
People are part of our growth and success story – from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
We celebrate strong performance with financial rewards, peer‑to‑peer recognition, and growth opportunities
At BridgeBio, we strive to provide a market‑competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi‑state employer, and this salary range may not reflect positions based in other states.
#J-18808-Ljbffr
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early‑stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life‑changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries and empower people to solve problems. If you’re someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we’ll ask “why not?” and help reengineer the future of biopharma.
Affiliate Overview Eidos Therapeutics, an affiliate within BridgeBio Pharma, is a commercial‑stage biopharmaceutical company focused on Transthyretin Amyloid Cardiomyopathy (ATTR‑CM).
What You’ll Do The Vice President of Global Supply Chain will be responsible for global end‑to‑end clinical supply chain activities related to managing supply of Investigational Product (IP) including packaging, labeling, distribution and demand forecasting for multiple clinical studies through all stages of clinical development. The role will also have responsibility for global end‑to‑end commercial supply chain activities, including the management of S&OP, Supply planning, Supplier (CMO, CPO, 3PL) management, inventory management, and partnership with Global Trade for Finished Good distribution. The role will partner closely with CMC/Manufacturing, Commercial, Clinical, and Quality Assurance teams and partner stakeholders to ensure timely and uninterrupted supply of clinical and commercial product. The individual must have the ability to manage global teams, experience in GxP industry, be an effective leader, and work efficiently in a fast‑paced environment.
Responsibilities
Manage a global team of supply chain professionals, responsible for both clinical and commercial end‑to‑end supply chain
Manage all aspects of commercial supply chain, including Drug Substance and Drug Product Contract Manufacturing Organizations (CMOs), Packaging and Labeling activities with Contract Packaging organizations (CPOs), Finished Good receiving, put away, storage and distribution activities at Third Part Logistics Providers (3PLs)
Coordinate logistics of material transfer for clinical and commercial drug substance, drug product and components to/from international CMOs/CPOs, managing exportation, applicable USDA/FDA licenses and permits, VAT recovery and customs brokers
Own the global Sales & Operations Planning (S&OP) process for all commercial products, coordinating with global market access team for demand planning, finance team for financial planning and driving ownership of final supply plan to be communicated to global partners
Own and actively manage the commercial supply plan, all commercial inventory, both in process and finished goods; manage shelf life and expiration
Own and manage all serialization activities for commercial products globally
Manage clinical packaging and labeling activities including label design, translation, production, distribution and inventory management
Provide clinical demand signals, translate the total demand into a demand forecast over time based on a clinical protocol or study overview
Prepare a clinical supply plan to support the demand, including determination of supply overage amounts, monitor inventory and provide regular inventory update to project teams
Monitor clinical drug expiry/retest dating; initiate inventory release and re‑supply, serving as the unblinded inventory manager
Manage domestic and international distribution and logistics for clinical programs, including importing and exporting clinical supplies and developing distribution instructions with clinical supply vendors
Support budget activities, including managing supplier contracts, PO generation and invoicing approvals for clinical and commercial purchases
Work collaboratively with QA to manage supply chain activities such as batch release, final release, temperature excursions and to support the investigation of any deviations in a timely manner
Work with CMC as a liaison to clinical operations and also on the evaluation of new CMOs or CPOs for commercial supply chain
Work with Global Trade & Distribution and global Finance teams to manage global 3PLs, ensuring quality Finished Good inventory management, distribution and logistics, sales and revenue reporting
Generate and maintain global SOPs in Veeva QMS and ensure updates and compliance with industry standards
Develop and maintain strong internal cross‑functional collaboration with stakeholders, such as CMC, Clinical Operations, Market Access, Finance, Quality, and Regulatory Affairs
Where You’ll Work This is a hybrid role and requires in‑office collaboration 2‑3x per week in our San Francisco Office.
Who You Are
At least fifteen (15) years of experience in Supply Chain Management and/or Manufacturing functions in the pharmaceutical and/or biotechnology industries. Title based on experience
Bachelor’s or Master’s Degree in a scientific discipline
Detailed understanding of the pharmaceutical business, including both clinical development and manufacturing and commercial manufacturing and supply chain
Proven experience with forecasting, demand/supply planning, inventory management, packaging, labeling and distribution including cold chain, import/export and reverse logistics
Proven experience managing and developing a team of professionals
Experience with SAP or similar ERP platform
Experience with product serialization, TraceLink or other similar platform and DSCSA standards
Experience with Veeva, or other similar QMS platform
Experience with clinical blinding practices
Experience in assisting set‑up of IRT systems for global clinical studies
Demonstrated skills in project management and vendor management
Working knowledge of drug development process (Phase I‑IV)
Working knowledge of current GMP/GCP/GDP guidance and regulations
Familiar with US and EU import/export regulations
Excellent attention to detail, strong data analysis, problem solving and decision‑making ability all while working in a fast‑paced and dynamic environment
Proven ability to effectively develop, communicate, and gain support for execution plans with a wide range of stakeholders
Ability to handle multiple projects simultaneously
APICS certification or supply chain education preferred
Other Information:
Position may require occasional evening and/or weekend commitment
Position may require occasional travel (up to 20%), domestic and international
Salary is competitive and commensurate with experience and qualifications
Rewarding Those Who Make the Mission Possible We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
Market leading compensation
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Referral program with $2,500 award for hired referrals
Comprehensive health care with 100% premiums covered – no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model – employees have the autonomy in where and how they do their work
Unlimited flexible paid time off – take the time that you need
Paid parental leave – 4 months for birthing parents & 2 months for non‑birthing parents
Flex spending accounts & company‑provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
Skill Development & Career Paths:
People are part of our growth and success story – from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
We celebrate strong performance with financial rewards, peer‑to‑peer recognition, and growth opportunities
At BridgeBio, we strive to provide a market‑competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi‑state employer, and this salary range may not reflect positions based in other states.
#J-18808-Ljbffr