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Natera

Senior/ Research Associate 2

Natera, San Carlos, California, United States, 94071

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Position Summary Natera is seeking a Senior/Research Associate 2 to support and coordinate workflow activities involved in the execution of molecular and genetic-based assays within the Molecular Biology Development team. The ideal candidate is a meticulous and motivated scientist with hands‑on experience in assay development, capable of thriving in a dynamic, fast‑paced environment to ensure the highest‑quality clinical assays are developed and launched for patient care. This position plays a key role in the research, development, and optimization of molecular workflows that contribute to Natera’s cutting‑edge products, including Signatera and new technologies in the cancer monitoring and detection space. The Senior Research Associate will work closely with scientists and engineers to execute experiments, perform analyses, and maintain efficient sample and data flow throughout development activities.

Primary Responsibilities

Independently execute in‑lab efforts both manually and using automated liquid handlers to develop non‑invasive nucleic acid‑based diagnostic tests.

Experience with automation systems, especially liquid handling platforms, is required.

Assist in the design, execution, and troubleshooting of laboratory workflows in collaboration with scientists, engineers, and cross‑functional teams.

Perform basic data analysis using tools such as Excel, JMP, or similar software.

Contribute to the preparation of reports and other deliverables.

Develop and maintain standard operating procedures (SOPs); provide training on established methods as needed.

Contribute to the optimization of new methods and technologies supporting next‑generation oncology monitoring assays.

Coordinate with internal teams (e.g., Laboratory Operations, Scientific Operations, CLIA) to plan and improve logistical workflow processes.

Maintain compliance with Natera’s training, security, and privacy standards, including HIPAA/PHI and general policy requirements.

Adhere to environmental, health and safety (EHS) guidelines and good laboratory practices (GLP).

Demonstrate flexibility in managing multiple priorities and perform additional duties as assigned.

Qualifications

BS/BA in a biological science or equivalent.

Minimum of 4 years Molecular Biology laboratory experience.

Minimum of 2–3 years of industry experience in an assay development department.

Knowledge, Skills, and Abilities

Hands‑on experience with nucleic acid techniques, including DNA manipulation, PCR, qPCR, DNA quantification, and analysis using LabChip and BioAnalyzer systems.

Strong background in Next Generation Sequencing (NGS) techniques, protocols, and data analysis workflows.

Whole blood processing (isolation and extraction experience).

Proficient in target enrichment, circulating cell‑free DNA/RNA (cfDNA/cfRNA) processing, and library preparation for sequencing applications.

Automation skill set is a must, including experience with developing or executing assays on automated liquid handling platforms.

Experience with reagent quality control (QC) and troubleshooting assay performance.

Practical knowledge of LIMS/database query tools.

Proficient in data analysis using Excel and related software.

Strong analytical, organizational, and problem‑solving abilities, with exceptional attention to detail.

Must have proven interpersonal, communication, computer, and technical skills.

Self‑motivated, adaptable, and results‑driven professional with a demonstrated track record of success in both independent and collaborative projects.

Pay Range San Carlos, CA: $68,100—$102,100 USD

Our Opportunity Natera™ is a global leader in cell‑free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics a standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

What We Offer

Competitive benefits including comprehensive medical, dental, vision, life, and disability plans for eligible employees and their dependents.

Employee families receive free testing and fertility care benefits.

Paid leave for pregnancy and baby bonding.

401(k) benefits and commuter benefits.

Generous employee referral program.

Equal Opportunity Employer All qualified applicants are encouraged to apply and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

California Residents Notice Link: https://www.natera.com/notice-of-data-collection-california-residents/

Contact & Safety Notice Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

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