Crescent Biopharma, Inc.
Senior/Principal Scientist, Immuno-Oncology Research & Development
Crescent Biopharma, Inc., Waltham, Massachusetts, United States, 02254
About Us
Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company’s pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody‑drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies either as single agents or as part of combination regimens to treat a range of solid tumors.
Position Overview Crescent Biopharma is seeking an experienced Senior/Principal Scientist, Immuno‑Oncology (IO) Research & Development. This individual will provide strategic and technical oversight for all aspects of Crescent’s novel immuno‑oncology drug discovery efforts from lead identification to preclinical development and commercialization. The ideal candidate is a creative and innovative scientist with a strong track record of leading the successful discovery and development of drug candidates across many biologics modalities, such as monoclonal antibodies, bispecific antibodies, and peptides in the field of immunology and/or oncology.
Responsibilities
Contribute the strategic approach for target selection, antibody discovery and therapeutic approach to identify and develop novel targeted immuno‑oncology therapeutics.
Provide scientific guidance and mentorship to a growing research team.
Lead technological innovations to drive continual improvements and optimization of Crescent's antibody and bispecific programs enabling continued success as the organization grows.
Effectively manage work conducted at CROs and external partners.
Represent the company at scientific conferences and author high‑impact peer reviewed publications.
Deliver research and development reports to support regulatory submissions (IND/IMPD, information requests, amendments, briefing books, BLA/MAA, etc.).
Education & Experience
Ph.D. in Life Science with at least 5 years of combined R&D experience from the biotech/biopharmaceutical industry and world‑class academic institutions with demonstrated career growth and experience gained in growing R&D organizations. M.S. with equivalent experience will also be considered.
Deep experience in drug discovery and development in immunology and/or immuno‑oncology.
Successful leadership of antibody and bispecific antibody programs from discovery to preclinical development and commercialization.
Background in immunology and/or immune‑oncology field(s).
Intellectually and scientifically curious, and a collaborative member of multi‑functional project teams.
Extremely scientifically rigorous and creative and ability to create an environment where imaginative and constructive dialog can flourish, conflict is well‑managed and complex issues are driven to full resolution.
Hands on experience with regulatory requirements for the development and approval of novel therapeutics in oncology.
What We Offer
Opportunity to join a mission‑driven team where you'll contribute to impactful work, take on varied responsibilities, and grow quickly in a dynamic environment.
Competitive compensation, including base salary, performance bonus, and equity.
100% employer‑paid benefits package.
Flexible PTO.
Two, one‑week company‑wide shutdowns each year.
A commitment to your professional development, with access to resources, mentorship, and growth opportunities.
The anticipated salary range for candidates for this role at the Sr Scientist level is $147,000 – $163,000 and at the Principal Scientist level is $163,000–$181,000. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.
Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company‑sponsored employee benefit programs: medical, dental, vision, life insurance, short‑ and long‑term disability. Subject to the terms of their respective plans, employees are eligible to participate in the Company’s savings plan (401(k)). This position is eligible to participate in the Company’s long‑term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation – Unlimited PTO; Sick time – 10 days per calendar year; Holiday pay, including two Company shutdowns; Parental Leave – 16 weeks within one year of the birth/adoption/foster care of a child; FMLA; Military Leave. Additional information can be found through the link below.
E‑Verify: Crescent Biopharma, Inc. uses E‑Verify to confirm the identity and employment eligibility of all new hires.
Crescent Biopharma is an Equal Opportunity Employer. We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender, sexual orientation, national origin, disability, veteran status, or any other protected status.
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Position Overview Crescent Biopharma is seeking an experienced Senior/Principal Scientist, Immuno‑Oncology (IO) Research & Development. This individual will provide strategic and technical oversight for all aspects of Crescent’s novel immuno‑oncology drug discovery efforts from lead identification to preclinical development and commercialization. The ideal candidate is a creative and innovative scientist with a strong track record of leading the successful discovery and development of drug candidates across many biologics modalities, such as monoclonal antibodies, bispecific antibodies, and peptides in the field of immunology and/or oncology.
Responsibilities
Contribute the strategic approach for target selection, antibody discovery and therapeutic approach to identify and develop novel targeted immuno‑oncology therapeutics.
Provide scientific guidance and mentorship to a growing research team.
Lead technological innovations to drive continual improvements and optimization of Crescent's antibody and bispecific programs enabling continued success as the organization grows.
Effectively manage work conducted at CROs and external partners.
Represent the company at scientific conferences and author high‑impact peer reviewed publications.
Deliver research and development reports to support regulatory submissions (IND/IMPD, information requests, amendments, briefing books, BLA/MAA, etc.).
Education & Experience
Ph.D. in Life Science with at least 5 years of combined R&D experience from the biotech/biopharmaceutical industry and world‑class academic institutions with demonstrated career growth and experience gained in growing R&D organizations. M.S. with equivalent experience will also be considered.
Deep experience in drug discovery and development in immunology and/or immuno‑oncology.
Successful leadership of antibody and bispecific antibody programs from discovery to preclinical development and commercialization.
Background in immunology and/or immune‑oncology field(s).
Intellectually and scientifically curious, and a collaborative member of multi‑functional project teams.
Extremely scientifically rigorous and creative and ability to create an environment where imaginative and constructive dialog can flourish, conflict is well‑managed and complex issues are driven to full resolution.
Hands on experience with regulatory requirements for the development and approval of novel therapeutics in oncology.
What We Offer
Opportunity to join a mission‑driven team where you'll contribute to impactful work, take on varied responsibilities, and grow quickly in a dynamic environment.
Competitive compensation, including base salary, performance bonus, and equity.
100% employer‑paid benefits package.
Flexible PTO.
Two, one‑week company‑wide shutdowns each year.
A commitment to your professional development, with access to resources, mentorship, and growth opportunities.
The anticipated salary range for candidates for this role at the Sr Scientist level is $147,000 – $163,000 and at the Principal Scientist level is $163,000–$181,000. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.
Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company‑sponsored employee benefit programs: medical, dental, vision, life insurance, short‑ and long‑term disability. Subject to the terms of their respective plans, employees are eligible to participate in the Company’s savings plan (401(k)). This position is eligible to participate in the Company’s long‑term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation – Unlimited PTO; Sick time – 10 days per calendar year; Holiday pay, including two Company shutdowns; Parental Leave – 16 weeks within one year of the birth/adoption/foster care of a child; FMLA; Military Leave. Additional information can be found through the link below.
E‑Verify: Crescent Biopharma, Inc. uses E‑Verify to confirm the identity and employment eligibility of all new hires.
Crescent Biopharma is an Equal Opportunity Employer. We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender, sexual orientation, national origin, disability, veteran status, or any other protected status.
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