University of California, San Francisco
Junior or Assistant Specialist
University of California, San Francisco, San Francisco, California, United States, 94199
Junior or Assistant Specialist – University of California, San Francisco
Location: San Francisco, CA
Summary We are seeking an enthusiastic and capable Junior/Assistant Specialist interested in contributing to and gaining experience in human synthetic biology and cell engineering. Under the direction of Professor Wendell Lim, the specialist will apply cutting‑edge approaches to develop next‑generation cell therapies, including smart immune cells designed to recognize and kill cancer cells or to treat other challenging diseases such as autoimmune disease and neurodegeneration. The selected candidate will contribute to a team in the performance of laboratory and investigative procedures by conducting a variety of experimental techniques such as molecular cloning, culture and engineering of primary humans and mouse cells, flow cytometry, and in vivo preclinical mouse models of disease. The successful candidate will receive detailed technical training and will execute cellular assays to collect, analyze and compile data in support of our research. Additionally, the specialist will be expected to assist with managing day‑to‑day lab operations, perform general lab duties and be a positive lab citizen. This is an outstanding opportunity for a highly motivated candidate seeking in‑depth experience in cutting‑edge biomedical research.
Learn More About Our Research https://limlab.ucsf.edu /
https://www.celldesigninstitute.org
Representative Essential Duties And Responsibilities
Assist scientists by performing various investigative procedures and operating a variety of instruments and other scientific equipment, including plate readers for absorbance or luminescence‑based assays, microscopes for live cell functional studies, PCR machines for gene amplification and cloning, flow cytometers and cell sorters for single‑cell analysis and isolation. Our group also leverages preclinical mouse models of cancer and autoimmune disease to test the efficacy of candidate cell therapies.
Collect, record, organize and verify the accuracy of data; perform calculations and prepare charts, graphs, and reports. May use software applications to assemble, manipulate and/or format data and test reports.
Configure and operate laboratory apparatus and instruments; read and record instrument data; tabulate data and keep laboratory records.
May order chemicals, reagents, and other laboratory supplies.
Participate in laboratory meetings and planning sessions, and present research updates to groups.
May maintain bacterial and tissue cultures for experimental purposes.
Read literature applicable to research areas as required.
Perform the duties of a Laboratory Assistant as required.
Qualifications Required
Excellent organizational and interpersonal communication skills (verbal and written)
Willingness and ability to learn new methods and skills for changing research priorities.
Ability to work independently and as a member of a research team.
Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Must have (or be in process of obtaining) a bachelor’s of science degree (or equivalent) in Molecular Biology, Biochemistry, Immunology, or related field or at least four years of research experience to be appointed at the Junior rank. Knowledge of Immunology is preferable but not required.
Must have (or be in process of obtaining) a master’s of science degree (or equivalent) in Molecular Biology, Biochemistry, Immunology, or related field, or a bachelor’s degree with three or more years of research experience to be appointed at the Assistant rank.
Candidates must meet the required qualifications at the time of appointment.
Candidate's CV must state qualifications (or if pending) upon submission.
Preferred
Experience in the design and assembly of DNA constructs (including modern molecular cloning techniques like Golden Gate or Gibson Assembly).
Experience with viral vectors, transposon vectors and/or CRISPR genome integration techniques for genetic engineering.
Experience with culture of mammalian cells, including tumor cell lines, primary immune cells (e.g., T cells) and/or stem cells.
Experience in flow cytometry and cell sorting.
Experience with animal experiments, including mouse tumor models (subcutaneous and intravenous injection).
Experience in immunology assays, such as cytotoxicity, cytokine secretion and general in‑vitro functional measurements of T cells.
Experience in fluorescence microscopy and imaging data analysis.
Knowledge, Understanding, Skills & Abilities
Generally experienced in laboratory duties, including both principles and practices associated with these duties and an understanding of the underlying scientific principles.
Ability to draft routine reports and keep accurate records of work performed.
Actively seeks opportunities to increase skills and expertise.
Able to learn complex tasks with general instruction. Able to use experience to perform a variety of new techniques.
Candidates must meet the qualifications at the time of hire. Candidate’s CV and/or cover letter must state basic qualification (or if pending) upon submission.
Physical Requirements
Occasionally lifts and/or carries objects weighing up to 20 pounds.
Occasionally stoops and bends.
Occasionally reaches and grasps with arms and hands.
Work involves possible exposure to malodorous vapors, low‑dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.
Long periods of standing and/or sitting.
Application Details Please apply online at
https://aprecruit.ucsf.edu/JPF05893 , with a CV, cover letter, and three references.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $55,000-$70,700.
Document Requirements:
Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
Cover Letter
Reference Requirements:
3 required (contact information only)
Equal Employment Opportunity The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.
'Misconduct' means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.
UC Sexual Violence and Sexual Harassment Policy
UC Anti-Discrimination Policy
APM - 035: Aff…
#J-18808-Ljbffr
Summary We are seeking an enthusiastic and capable Junior/Assistant Specialist interested in contributing to and gaining experience in human synthetic biology and cell engineering. Under the direction of Professor Wendell Lim, the specialist will apply cutting‑edge approaches to develop next‑generation cell therapies, including smart immune cells designed to recognize and kill cancer cells or to treat other challenging diseases such as autoimmune disease and neurodegeneration. The selected candidate will contribute to a team in the performance of laboratory and investigative procedures by conducting a variety of experimental techniques such as molecular cloning, culture and engineering of primary humans and mouse cells, flow cytometry, and in vivo preclinical mouse models of disease. The successful candidate will receive detailed technical training and will execute cellular assays to collect, analyze and compile data in support of our research. Additionally, the specialist will be expected to assist with managing day‑to‑day lab operations, perform general lab duties and be a positive lab citizen. This is an outstanding opportunity for a highly motivated candidate seeking in‑depth experience in cutting‑edge biomedical research.
Learn More About Our Research https://limlab.ucsf.edu /
https://www.celldesigninstitute.org
Representative Essential Duties And Responsibilities
Assist scientists by performing various investigative procedures and operating a variety of instruments and other scientific equipment, including plate readers for absorbance or luminescence‑based assays, microscopes for live cell functional studies, PCR machines for gene amplification and cloning, flow cytometers and cell sorters for single‑cell analysis and isolation. Our group also leverages preclinical mouse models of cancer and autoimmune disease to test the efficacy of candidate cell therapies.
Collect, record, organize and verify the accuracy of data; perform calculations and prepare charts, graphs, and reports. May use software applications to assemble, manipulate and/or format data and test reports.
Configure and operate laboratory apparatus and instruments; read and record instrument data; tabulate data and keep laboratory records.
May order chemicals, reagents, and other laboratory supplies.
Participate in laboratory meetings and planning sessions, and present research updates to groups.
May maintain bacterial and tissue cultures for experimental purposes.
Read literature applicable to research areas as required.
Perform the duties of a Laboratory Assistant as required.
Qualifications Required
Excellent organizational and interpersonal communication skills (verbal and written)
Willingness and ability to learn new methods and skills for changing research priorities.
Ability to work independently and as a member of a research team.
Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Must have (or be in process of obtaining) a bachelor’s of science degree (or equivalent) in Molecular Biology, Biochemistry, Immunology, or related field or at least four years of research experience to be appointed at the Junior rank. Knowledge of Immunology is preferable but not required.
Must have (or be in process of obtaining) a master’s of science degree (or equivalent) in Molecular Biology, Biochemistry, Immunology, or related field, or a bachelor’s degree with three or more years of research experience to be appointed at the Assistant rank.
Candidates must meet the required qualifications at the time of appointment.
Candidate's CV must state qualifications (or if pending) upon submission.
Preferred
Experience in the design and assembly of DNA constructs (including modern molecular cloning techniques like Golden Gate or Gibson Assembly).
Experience with viral vectors, transposon vectors and/or CRISPR genome integration techniques for genetic engineering.
Experience with culture of mammalian cells, including tumor cell lines, primary immune cells (e.g., T cells) and/or stem cells.
Experience in flow cytometry and cell sorting.
Experience with animal experiments, including mouse tumor models (subcutaneous and intravenous injection).
Experience in immunology assays, such as cytotoxicity, cytokine secretion and general in‑vitro functional measurements of T cells.
Experience in fluorescence microscopy and imaging data analysis.
Knowledge, Understanding, Skills & Abilities
Generally experienced in laboratory duties, including both principles and practices associated with these duties and an understanding of the underlying scientific principles.
Ability to draft routine reports and keep accurate records of work performed.
Actively seeks opportunities to increase skills and expertise.
Able to learn complex tasks with general instruction. Able to use experience to perform a variety of new techniques.
Candidates must meet the qualifications at the time of hire. Candidate’s CV and/or cover letter must state basic qualification (or if pending) upon submission.
Physical Requirements
Occasionally lifts and/or carries objects weighing up to 20 pounds.
Occasionally stoops and bends.
Occasionally reaches and grasps with arms and hands.
Work involves possible exposure to malodorous vapors, low‑dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.
Long periods of standing and/or sitting.
Application Details Please apply online at
https://aprecruit.ucsf.edu/JPF05893 , with a CV, cover letter, and three references.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $55,000-$70,700.
Document Requirements:
Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
Cover Letter
Reference Requirements:
3 required (contact information only)
Equal Employment Opportunity The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.
'Misconduct' means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.
UC Sexual Violence and Sexual Harassment Policy
UC Anti-Discrimination Policy
APM - 035: Aff…
#J-18808-Ljbffr