Pfizer, S.A. de C.V
Locations:
United States - New York - New York City
United States - Pennsylvania - Collegeville
United States - Massachusetts - Cambridge
United States - Connecticut - Groton
We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.
ROLE SUMMARY
Develops model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision‑making, in collaboration with partners. Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development. Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety. Supports and/or develops pharmacometrics tools, automation workflows, software, and related business processes. ROLE RESPONSIBILITIES
Provide support in the development of quantitative methodology, pharmacometrics tools, software, hardware, and/or related business processes. With guidance, provide MIDD expertise on multidisciplinary development teams, working closely with clinical pharmacologists, clinicians, and statisticians to create MIDD plans that include assessments of a drug’s efficacy, safety, and commercial viability. Responsible for the planning and execution of relevant quantitative analyses which may include population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure‑response, disease progression modelling, model‑based meta‑analysis, and decision analysis for multiple analyses supporting a program. Prepare formal presentations and written reports to Pfizer standards. Contribute to regulatory documents (summary documents, briefing books, regulatory responses). Have a good understanding of literature, government guidelines, and internal guidance as relates to pharmacometrics and MIDD. Contribute to the development or improvement of tools, processes and methodology, including involvement in internal cross‑functional workgroups or initiatives, external alliances or committees, consortia and academic relationships. BASIC QUALIFICATIONS
PhD or equivalent degree with strong quantitative skills (e.g., pharmacometrics, pharmacokinetics, mechanistic modelling/systems pharmacology, statistics). 3 years or more of experience in a quantitative field. Expertise in analysis and programming software (e.g., Nonmem, R). Experience in pharmacometric analyses. Good communication skills (written, oral). Drug development and/or regulatory experience. Publications in relevant discipline. Good understanding of pharmacokinetics, pharmacodynamics and statistical principles. Demonstrates a breadth of diverse leadership experiences and capabilities, including the ability to influence and collaborate with peers, develop and coach others, and oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PREFERRED QUALIFICATIONS
Experience using Nonmem, R and/or PsN softwares is preferred. Candidates from alternative backgrounds (e.g., mathematics, engineering, system biology, medicine) will be considered if they can demonstrate relevant experience and expertise. ORGANIZATIONAL RELATIONSHIPS
Reports to Pharmacometrics Group Leader within the line organization of Pharmacometrics and Systems Pharmacology, TCS. Matrixed relationships particularly with Clinical Pharmacology Leads, Clinicians, Statisticians, and colleagues from Programming groups and other groups as required. PHYSICAL/MENTAL REQUIREMENTS
Sitting, ability to perform complex data analyses. ADDITIONAL JOB DETAILS
Last date to apply is December 18, 2025. Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week. EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States.
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Develops model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision‑making, in collaboration with partners. Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development. Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety. Supports and/or develops pharmacometrics tools, automation workflows, software, and related business processes. ROLE RESPONSIBILITIES
Provide support in the development of quantitative methodology, pharmacometrics tools, software, hardware, and/or related business processes. With guidance, provide MIDD expertise on multidisciplinary development teams, working closely with clinical pharmacologists, clinicians, and statisticians to create MIDD plans that include assessments of a drug’s efficacy, safety, and commercial viability. Responsible for the planning and execution of relevant quantitative analyses which may include population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure‑response, disease progression modelling, model‑based meta‑analysis, and decision analysis for multiple analyses supporting a program. Prepare formal presentations and written reports to Pfizer standards. Contribute to regulatory documents (summary documents, briefing books, regulatory responses). Have a good understanding of literature, government guidelines, and internal guidance as relates to pharmacometrics and MIDD. Contribute to the development or improvement of tools, processes and methodology, including involvement in internal cross‑functional workgroups or initiatives, external alliances or committees, consortia and academic relationships. BASIC QUALIFICATIONS
PhD or equivalent degree with strong quantitative skills (e.g., pharmacometrics, pharmacokinetics, mechanistic modelling/systems pharmacology, statistics). 3 years or more of experience in a quantitative field. Expertise in analysis and programming software (e.g., Nonmem, R). Experience in pharmacometric analyses. Good communication skills (written, oral). Drug development and/or regulatory experience. Publications in relevant discipline. Good understanding of pharmacokinetics, pharmacodynamics and statistical principles. Demonstrates a breadth of diverse leadership experiences and capabilities, including the ability to influence and collaborate with peers, develop and coach others, and oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PREFERRED QUALIFICATIONS
Experience using Nonmem, R and/or PsN softwares is preferred. Candidates from alternative backgrounds (e.g., mathematics, engineering, system biology, medicine) will be considered if they can demonstrate relevant experience and expertise. ORGANIZATIONAL RELATIONSHIPS
Reports to Pharmacometrics Group Leader within the line organization of Pharmacometrics and Systems Pharmacology, TCS. Matrixed relationships particularly with Clinical Pharmacology Leads, Clinicians, Statisticians, and colleagues from Programming groups and other groups as required. PHYSICAL/MENTAL REQUIREMENTS
Sitting, ability to perform complex data analyses. ADDITIONAL JOB DETAILS
Last date to apply is December 18, 2025. Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week. EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States.
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