Mayo Clinic
Principal Information Security Engineer - IS Mod
Mayo Clinic, Rochester, Minnesota, us, 55905
Principal Information Security Engineer - IS Mod
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Principal Information Security Engineer - IS Mod
role at
Mayo Clinic
City: Rochester, State: MN, Remote: Yes, Department: Information Security
Benefits Highlights
Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.
Responsibilities
Lead the technical aspects of incident detection, analysis, containment, eradication, and recovery for information security incidents.
Develop and maintain incident response plans, playbooks, and procedures, ensuring alignment with industry best practices and regulatory requirements.
Coordinate investigations into suspicious activities, malware attacks, and advanced persistent threats (APTs).
Serve as the primary escalation point for complex incidents, providing expert guidance and decision‑making during critical events.
Collaborate with security operations, threat intelligence, and IT teams to improve detection capabilities and reduce response times.
Conduct post‑incident reviews, root cause analyses, and lessons‑learned sessions to strengthen the organization’s security posture.
Mentor and train incident response team members, fostering technical growth and knowledge sharing.
Stay current with emerging threats, vulnerabilities, and attack techniques, recommending proactive measures to mitigate risks.
Prepare and deliver detailed reports, metrics, and presentations to senior leadership and stakeholders.
Perform forensic analysis, malware reverse engineering, and network security monitoring.
Qualifications
Master’s degree with three years of experience OR Bachelor’s degree in Computer Science, Information Systems, Engineering or related major and a minimum of five years of experience in the information security field.
Strong understanding of information security tools, server configurations, and controls.
Experience with installing, configuring, testing, deploying, and maintaining infrastructure hardware and software to secure the enterprise.
Ability to collect, process, preserve, analyze, and present computer‑related evidence.
Advanced technical opinions on security tools, trends, and controls supported by documented evidence.
Deep knowledge of standard operating procedures, workflows, and supporting technology across critical user areas.
Capacity to work independently and seek advice or assistance when needed.
Must hold at least one of the following certifications at time of hire: CISSP, GSEC, CISM, HCISPP, OSCP.
Exemption Status: Exempt
Compensation: $145,225.60 – $210,558.40 per year
Benefits Eligible: Yes
Schedule: Full Time, Monday – Friday, 8 am – 5 pm (Weekends and nights as needed with on‑call responsibilities)
Equal Opportunity: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status.
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Principal Information Security Engineer - IS Mod
role at
Mayo Clinic
City: Rochester, State: MN, Remote: Yes, Department: Information Security
Benefits Highlights
Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.
Responsibilities
Lead the technical aspects of incident detection, analysis, containment, eradication, and recovery for information security incidents.
Develop and maintain incident response plans, playbooks, and procedures, ensuring alignment with industry best practices and regulatory requirements.
Coordinate investigations into suspicious activities, malware attacks, and advanced persistent threats (APTs).
Serve as the primary escalation point for complex incidents, providing expert guidance and decision‑making during critical events.
Collaborate with security operations, threat intelligence, and IT teams to improve detection capabilities and reduce response times.
Conduct post‑incident reviews, root cause analyses, and lessons‑learned sessions to strengthen the organization’s security posture.
Mentor and train incident response team members, fostering technical growth and knowledge sharing.
Stay current with emerging threats, vulnerabilities, and attack techniques, recommending proactive measures to mitigate risks.
Prepare and deliver detailed reports, metrics, and presentations to senior leadership and stakeholders.
Perform forensic analysis, malware reverse engineering, and network security monitoring.
Qualifications
Master’s degree with three years of experience OR Bachelor’s degree in Computer Science, Information Systems, Engineering or related major and a minimum of five years of experience in the information security field.
Strong understanding of information security tools, server configurations, and controls.
Experience with installing, configuring, testing, deploying, and maintaining infrastructure hardware and software to secure the enterprise.
Ability to collect, process, preserve, analyze, and present computer‑related evidence.
Advanced technical opinions on security tools, trends, and controls supported by documented evidence.
Deep knowledge of standard operating procedures, workflows, and supporting technology across critical user areas.
Capacity to work independently and seek advice or assistance when needed.
Must hold at least one of the following certifications at time of hire: CISSP, GSEC, CISM, HCISPP, OSCP.
Exemption Status: Exempt
Compensation: $145,225.60 – $210,558.40 per year
Benefits Eligible: Yes
Schedule: Full Time, Monday – Friday, 8 am – 5 pm (Weekends and nights as needed with on‑call responsibilities)
Equal Opportunity: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status.
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