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Exelixis

Senior Scientist I (Medicinal Chemistry)

Exelixis, Alameda, California, United States, 94501

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SUMMARY/JOB PURPOSE Seeking highly skilled and motivated synthetic chemists to join our medicinal chemistry drug discovery team. The ideal candidates will be experienced in the design and execution of multi-step organic synthesis as well as the purification, analysis and characterization of small molecule target compounds.

ESSENTIAL DUTIES AND RESPONSIBILITIES

Design, synthesis, purification and characterization of small molecule lead compounds

Troubleshoot and optimize synthetic routes

Participate in group, project team and departmental research meetings

Maintain proper laboratory notebooks in accordance with company policies and practices

Comply with safe laboratory practices and EH&S guidelines

Contribute to the writing of technical documents, patents, scientific manuscripts, etc.

SUPERVISORY RESPONSIBILITIES

No supervisory responsibilities

EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS

Bachelor’s degree in related discipline and a minimum of seven years of related experience; or,

Master’s degree in related discipline and a minimum of five years of related experience; or

PhD degree in related discipline and zero or more years of related experience; or

Equivalent combination of education and experience.

Experience for the Ideal Candidate

Experience designing and executing multi-step synthesis pathways

Experience using chromatographic purification techniques (flash chromatography, preparative HPLC, etc.)

Experience using modern analytical techniques (NMR, LC-MS, etc.) Knowledge/Skills

Strong organic and medicinal chemistry bench skills

Solid knowledge of synthetic organic chemistry reaction mechanisms and reactivity

Demonstrates independence in the laboratory

Efficient use of scientific literature and chemical/scientific databases

Good interpersonal skills, flexibility and works well within a team environment

Excellent written and verbal communication skills

WORKING CONDITIONS

Environment: primarily working in laboratories or in office

Exposures encountered, such as hazardous materials, extreme cold.

Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $116,000 - $165,500 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors. In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

If you like wild growth and working with happy, enthusiastic over-achievers, you'll enjoy your career with us!

DISCLAIMER The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

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