Dana-Farber Cancer Institute
Research Technician: D'Andrea Lab
Dana-Farber Cancer Institute, Boston, Massachusetts, us, 02298
Overview
The Research Technician will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. They will help set up, operate and maintain laboratory instruments and equipment, monitor experiments, make observations, calculate and record results.
The D’Andrea Lab investigates the mechanisms underlying chromosome instability and cancer susceptibility. Our research focuses on the molecular signaling pathways that regulate the DNA damage response in mammalian cells. Disruption of these pathways—whether through germline or somatic mutations—can lead to genomic instability, sensitivity to ionizing radiation, and defects in cell cycle checkpoints and DNA repair. Such alterations are frequently observed in cancer and contribute to increased mutation rates and tumor progression. The lab employs a wide range of innovative technologies to measure DNA damage responses in cancer cell lines, including cytotoxicity assays and proteomic biomarker analyses.
The Technician will support postdoctoral fellows and scientists in conducting experiments of varying complexity, develop critical‑thinking skills, and gain experience in designing rigorous, well‑controlled experiments.
Opportunities to contribute to scientific publications as a co‑author are available.
Responsibilities
Clean, maintain, and prepare laboratory work areas and supplies.
Assist with inventory management and ordering reagents.
Ensure compliance with laboratory safety protocols and institutional Environmental Health and Safety (EHS) guidelines.
Maintain a detailed and organized laboratory notebook documenting all experimental procedures, observations, and results.
Culture, expand, and cryopreserve a variety of cancer cell lines under sterile conditions.
Design, optimize, and perform cell‑based assays to investigate target biology and evaluate experimental hypotheses.
Participate in lab meetings, group discussions, and institute‑wide seminars with invited speakers.
Ensure adherence to EHS guidelines and laboratory‑specific standard operating procedures; monitor compliance and promote safe laboratory practices.
Qualifications
Minimum Bachelor’s / Master’s degree required with a major in biology or chemistry.
Knowledge of information and techniques related to biology, chemistry, or medicine is preferred.
Excellent communication skills (written and verbal) and ability to work with a wide variety of faculty and staff.
Ability to analyze information and use logic to address work‑related issues and problems.
Attention to detail and thoroughness in completing work tasks.
Ability to work within a team environment.
Some computational biology experience is a plus.
Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and the candidate’s relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$47,500 – $51,300
Foundational Information Located in Boston and the surrounding communities, Dana‑Farber Cancer Institute is a leader in life‑changing breakthroughs in cancer research and patient care. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high‑risk and underserved populations.
EEOC Statement Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
Seniority Level Entry level
Employment Type Full‑time
Job Function Research, Analyst, and Information Technology
Industries Hospitals and Health Care
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The D’Andrea Lab investigates the mechanisms underlying chromosome instability and cancer susceptibility. Our research focuses on the molecular signaling pathways that regulate the DNA damage response in mammalian cells. Disruption of these pathways—whether through germline or somatic mutations—can lead to genomic instability, sensitivity to ionizing radiation, and defects in cell cycle checkpoints and DNA repair. Such alterations are frequently observed in cancer and contribute to increased mutation rates and tumor progression. The lab employs a wide range of innovative technologies to measure DNA damage responses in cancer cell lines, including cytotoxicity assays and proteomic biomarker analyses.
The Technician will support postdoctoral fellows and scientists in conducting experiments of varying complexity, develop critical‑thinking skills, and gain experience in designing rigorous, well‑controlled experiments.
Opportunities to contribute to scientific publications as a co‑author are available.
Responsibilities
Clean, maintain, and prepare laboratory work areas and supplies.
Assist with inventory management and ordering reagents.
Ensure compliance with laboratory safety protocols and institutional Environmental Health and Safety (EHS) guidelines.
Maintain a detailed and organized laboratory notebook documenting all experimental procedures, observations, and results.
Culture, expand, and cryopreserve a variety of cancer cell lines under sterile conditions.
Design, optimize, and perform cell‑based assays to investigate target biology and evaluate experimental hypotheses.
Participate in lab meetings, group discussions, and institute‑wide seminars with invited speakers.
Ensure adherence to EHS guidelines and laboratory‑specific standard operating procedures; monitor compliance and promote safe laboratory practices.
Qualifications
Minimum Bachelor’s / Master’s degree required with a major in biology or chemistry.
Knowledge of information and techniques related to biology, chemistry, or medicine is preferred.
Excellent communication skills (written and verbal) and ability to work with a wide variety of faculty and staff.
Ability to analyze information and use logic to address work‑related issues and problems.
Attention to detail and thoroughness in completing work tasks.
Ability to work within a team environment.
Some computational biology experience is a plus.
Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and the candidate’s relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$47,500 – $51,300
Foundational Information Located in Boston and the surrounding communities, Dana‑Farber Cancer Institute is a leader in life‑changing breakthroughs in cancer research and patient care. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high‑risk and underserved populations.
EEOC Statement Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
Seniority Level Entry level
Employment Type Full‑time
Job Function Research, Analyst, and Information Technology
Industries Hospitals and Health Care
#J-18808-Ljbffr