Bicara Therapeutics
Vice President, Head of US Medical Affairs
Bicara Therapeutics, Boston, Massachusetts, us, 02298
Vice President, Head of US Medical Affairs
Join Bicara Therapeutics to apply for the
Vice President, Head of US Medical Affairs
position.
Base Pay Range $330,000.00/yr - $415,000.00/yr
Position Overview Bicara Therapeutics is seeking an experienced and strategic Vice President, Head of US Medical Affairs to lead and shape the company's US medical affairs function. This newly created role is critical in establishing a robust scientific and clinical foundation to prepare the external landscape for the successful launch preparation and commercialization of ficerafusp alfa, Bicara’s lead asset in R/M HNSCC. The position involves building strong external relationships, providing medical insights, and ensuring the company is positioned as a credible and trusted leader in its therapeutic area.
Location:
Boston, hybrid schedule three in-office days per week.
Responsibilities
Develop and execute the US medical affairs strategy aligned with global objectives and commercialization plans.
Provide scientific and clinical expertise to internal teams, external partners, and key stakeholders to support the US launch of ficerafusp alfa.
Lead, build, and manage a high‑performing Medical Affairs team within the US region.
Foster relationships with key opinion leaders, healthcare providers, regulatory authorities, and patient advocacy groups.
Collaborate with Global Medical Affairs, R&D, Commercial, Regulatory, and other functions to ensure scientific accuracy and compliance.
Oversee planning and execution of scientific communications, educational programs, and medical information initiatives.
Provide strategic direction and oversight for US Investigator‑Initiated Trials, aligning with global medical strategies.
Provide medical insights for evidence generation activities, including observational studies and real‑world data initiatives.
Ensure all medical activities comply with applicable regulations, industry standards, and ethical guidelines.
Represent the company at scientific conferences, advisory boards, and industry forums.
Stay abreast of advances in the external medical landscape, competitive developments, and clinical trial outcomes.
Qualifications
Advanced degree required: MD (strongly preferred), PhD, or PharmD.
Minimum 15 years of medical affairs experience in biopharma, including launch‑stage assets.
Familiarity with oncology is advantageous; clinical or research expertise in oncology or rare diseases preferred.
History of building trusted KOL networks and influencing scientific communities across multiple regions.
Strong track record of evidence generation, publication leadership, and external communications.
Comfortable operating in a growth‑stage biotech environment with dynamic priorities.
Willingness to travel internationally (up to 30%) and work flexibly in a hybrid setting.
Company Overview Bicara Therapeutics is a clinical‑stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara’s lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR) directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF‑β). Through this dual‑targeting mechanism, ficerafusp alfa has the potential to exert potent anti‑tumor activity by simultaneously blocking both cancer cell‑intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF‑β signaling within the tumor microenvironment. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types. For more information, please visit www.bicara.com or follow us on LinkedIn or X.
Equal Employment Opportunity Statement Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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Vice President, Head of US Medical Affairs
position.
Base Pay Range $330,000.00/yr - $415,000.00/yr
Position Overview Bicara Therapeutics is seeking an experienced and strategic Vice President, Head of US Medical Affairs to lead and shape the company's US medical affairs function. This newly created role is critical in establishing a robust scientific and clinical foundation to prepare the external landscape for the successful launch preparation and commercialization of ficerafusp alfa, Bicara’s lead asset in R/M HNSCC. The position involves building strong external relationships, providing medical insights, and ensuring the company is positioned as a credible and trusted leader in its therapeutic area.
Location:
Boston, hybrid schedule three in-office days per week.
Responsibilities
Develop and execute the US medical affairs strategy aligned with global objectives and commercialization plans.
Provide scientific and clinical expertise to internal teams, external partners, and key stakeholders to support the US launch of ficerafusp alfa.
Lead, build, and manage a high‑performing Medical Affairs team within the US region.
Foster relationships with key opinion leaders, healthcare providers, regulatory authorities, and patient advocacy groups.
Collaborate with Global Medical Affairs, R&D, Commercial, Regulatory, and other functions to ensure scientific accuracy and compliance.
Oversee planning and execution of scientific communications, educational programs, and medical information initiatives.
Provide strategic direction and oversight for US Investigator‑Initiated Trials, aligning with global medical strategies.
Provide medical insights for evidence generation activities, including observational studies and real‑world data initiatives.
Ensure all medical activities comply with applicable regulations, industry standards, and ethical guidelines.
Represent the company at scientific conferences, advisory boards, and industry forums.
Stay abreast of advances in the external medical landscape, competitive developments, and clinical trial outcomes.
Qualifications
Advanced degree required: MD (strongly preferred), PhD, or PharmD.
Minimum 15 years of medical affairs experience in biopharma, including launch‑stage assets.
Familiarity with oncology is advantageous; clinical or research expertise in oncology or rare diseases preferred.
History of building trusted KOL networks and influencing scientific communities across multiple regions.
Strong track record of evidence generation, publication leadership, and external communications.
Comfortable operating in a growth‑stage biotech environment with dynamic priorities.
Willingness to travel internationally (up to 30%) and work flexibly in a hybrid setting.
Company Overview Bicara Therapeutics is a clinical‑stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara’s lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR) directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF‑β). Through this dual‑targeting mechanism, ficerafusp alfa has the potential to exert potent anti‑tumor activity by simultaneously blocking both cancer cell‑intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF‑β signaling within the tumor microenvironment. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types. For more information, please visit www.bicara.com or follow us on LinkedIn or X.
Equal Employment Opportunity Statement Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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