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Viridian Therapeutics, Inc.

Principal Scientist

Viridian Therapeutics, Inc., Waltham, Massachusetts, United States, 02254

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Principal Scientist (Contract to hire) Viridian Therapeutics, Inc.

This role may be based in our Waltham, MA headquarters, which would be a hybrid role, or it can also be fully remote. Our office-based employees are required to work in the office three (3) days a week. If remote, travel to headquarters for meetings would be required at the discretion of management.

This role is a contract-to-hire position.

Viridian Therapeutics, Inc. provided pay range This range is provided by Viridian Therapeutics, Inc.. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range $163,000.00/yr - $200,000.00/yr

Company Overview At Viridian, we are focused on developing best-in-class medicines for people living with autoimmune and rare diseases. Leveraging our team’s expertise in antibody discovery and engineering, we have created a robust pipeline of differentiated investigational therapeutic candidates for well-validated targets.

Reporting to the VP, Clinical Pharmacology, the Principal Scientist will work with Discovery Research and Development team members, to support PPK/PKPD/ER dataset preparation and exploratory data visualization, across early and late-stage programs.

Responsibilities

Clean PK/Immunogenecity related datasets

Transform the relevant STDM and ADaM datasets, and other sources of data to enable PPK, PKPD and ER analyses

Develop SAS (or R) codes to perform data visualization, descriptive statistical summary in TLFs

Ensure dataset formatted according to CDISC standard

Collaborate with biostatistics programmers, statisticians, and pharmacometricians, to ensure data consistency and accuracy for general PK, PK/PD and ER analyses

Stay informed with the emerging literature in programming approaches in PMx field

Maintain current understanding of global regulatory expectations for CDISC requirements

Requirements

Requires an MS or PhD or equivalent in educational background in Statistics, Mathematics, Informatics, Chemical engineer, Computer Science, Pharmaceutical Science, or a related field with 10+ (MS degree) or 5+ (PhD) years of clinical pharmacology related programming or data science experience

Seasoned in SAS programming (or R)

Experienced with CDISC (eg, STDM, ADaM) standards, and experienced with Clinical Pharmacology related datasets (eg, PC, adpc, adpp, and PPK/ER datasets)

Demonstrated ability to handle uncleaned data, identify data issues, and implement different programming procedures according to the pharmacometrics modelling needs

Seniority level Mid-Senior level

Employment type Contract

Job function Research

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