R&D Partners
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Base pay range
$99,902.00/yr - $124,883.00/yr Biotechnology client is seeking a highly motivated Scientist for molecular cloning, cell culture, FPLC purification and antibody engineering and characterization. The qualified candidate will join a team of scientists focused on monoclonal antibody development for In Vitro Diagnostics and CDx assay. This position will be actively participating in antibody development, engineering, production and characterization. Job function requires the ability to evaluate, summarize and report study results, make independent decision and collaborate with teams at multiple sites. This is a 12-month contract in Pleasanton, California. Responsibilities
Plans and/or manages smaller, less complex local projects (e.g. with moderate project management complexity, problem definition, and/or short to medium term implications). Participates in project teams across the R&D department and functional groups. Can represent the Team Lead in project teams in his/her absence on instruction. Ensures that quality standards are met and plans and coordinates the performance of tasks largely independently. Is aware of new developments in the field and refers to the possible use of these in diagnostics. Contributes to collaboration and close networking within the departments as part of R&D projects. Analyzes and interprets the R&D results largely independently and presents them to the relevant committees within their own function. Uses specified strategies to resolve problems and acts within defined guidelines. Qualifications
Bachelor's degree in scientific discipline and 5+ years of biotechnology/pharmaceuticals industry experience. Experience and in-depth knowledge in monoclonal antibody development and antibody engineering. Proficiency in standard cloning techniques (e.g., PCR, restriction/ligation, Gibson assembly) for subcloning antibody sequences into mammalian expression vectors. Familiarity with antibody sequences and sequence analysis software. Significant experience with transient protein expression in mammalian cell culture systems (e.g., HEK293, CHO). Experience with antibody purification and characterization (eg. FPLC purification, HPLC, ELISA, SDS‑PAGE, WB, IHC). Domain knowledge in oncology, immunology, or protein chemistry. Practical experience using computational tools (e.g., PyMOL, VMD) for structure‑based analysis of antibodies. Ability to interpret structural data (PDB files) and relate it directly to experimental outcomes (e.g., binding, stability). Knowledge of biophysical characterization techniques (eg. DSC, DLS) to assess protein structural integrity and stability. Experience with computational protein engineering and antibody epitope modeling. Experience with advanced protein modifications analysis and their impact on function. Familiarity with formulation and stability studies for final antibody products. Benefits
Medical insurance – PPO, HMO & HSA 401k plan Employee Assistance Program Long‑term disability Weekly payroll Online timecard approval R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies. R&D Partners is an equal‑opportunity employer. Seniority level
Associate Employment type
Contract Job function
Research Industries
Staffing and Recruiting and Biotechnology Research
#J-18808-Ljbffr
$99,902.00/yr - $124,883.00/yr Biotechnology client is seeking a highly motivated Scientist for molecular cloning, cell culture, FPLC purification and antibody engineering and characterization. The qualified candidate will join a team of scientists focused on monoclonal antibody development for In Vitro Diagnostics and CDx assay. This position will be actively participating in antibody development, engineering, production and characterization. Job function requires the ability to evaluate, summarize and report study results, make independent decision and collaborate with teams at multiple sites. This is a 12-month contract in Pleasanton, California. Responsibilities
Plans and/or manages smaller, less complex local projects (e.g. with moderate project management complexity, problem definition, and/or short to medium term implications). Participates in project teams across the R&D department and functional groups. Can represent the Team Lead in project teams in his/her absence on instruction. Ensures that quality standards are met and plans and coordinates the performance of tasks largely independently. Is aware of new developments in the field and refers to the possible use of these in diagnostics. Contributes to collaboration and close networking within the departments as part of R&D projects. Analyzes and interprets the R&D results largely independently and presents them to the relevant committees within their own function. Uses specified strategies to resolve problems and acts within defined guidelines. Qualifications
Bachelor's degree in scientific discipline and 5+ years of biotechnology/pharmaceuticals industry experience. Experience and in-depth knowledge in monoclonal antibody development and antibody engineering. Proficiency in standard cloning techniques (e.g., PCR, restriction/ligation, Gibson assembly) for subcloning antibody sequences into mammalian expression vectors. Familiarity with antibody sequences and sequence analysis software. Significant experience with transient protein expression in mammalian cell culture systems (e.g., HEK293, CHO). Experience with antibody purification and characterization (eg. FPLC purification, HPLC, ELISA, SDS‑PAGE, WB, IHC). Domain knowledge in oncology, immunology, or protein chemistry. Practical experience using computational tools (e.g., PyMOL, VMD) for structure‑based analysis of antibodies. Ability to interpret structural data (PDB files) and relate it directly to experimental outcomes (e.g., binding, stability). Knowledge of biophysical characterization techniques (eg. DSC, DLS) to assess protein structural integrity and stability. Experience with computational protein engineering and antibody epitope modeling. Experience with advanced protein modifications analysis and their impact on function. Familiarity with formulation and stability studies for final antibody products. Benefits
Medical insurance – PPO, HMO & HSA 401k plan Employee Assistance Program Long‑term disability Weekly payroll Online timecard approval R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies. R&D Partners is an equal‑opportunity employer. Seniority level
Associate Employment type
Contract Job function
Research Industries
Staffing and Recruiting and Biotechnology Research
#J-18808-Ljbffr