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Apex Systems

Bioinformatics Scientist

Apex Systems, Natick, Massachusetts, us, 01760

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Computational Biologist – Obesity Research Boston, MA ($138,000.00-$224,400.00) 2 weeks ago

This range is provided by Apex Systems. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range $110,000.00/yr - $125,000.00/yr

Job Description A fast‑paced biotech team is seeking a Computational Biologist to lead bioinformatics efforts in antibody discovery and engineering. This role is ideal for someone who thrives at the intersection of data science and molecular biology, and is excited to contribute to the development of novel biologics.

Key Responsibilities

Analyze genomic and RNA‑Seq datasets from public repositories to identify new therapeutic targets

Oversee external efforts to verify gene sequences not yet available in public databases

Lead development of intuitive databases housing antibody repertoire sequences

Design and implement streamlined data entry workflows in Benchling for improved organization and accessibility

Apply in‑silico design strategies and software tools to remediate antibody sequence liabilities and enhance biophysical properties

Support external collaborations focused on machine learning applications in antibody discovery

Curate and integrate relevant genomic and transcriptomic datasets

Analyze antibody libraries using clustering methods such as clonotyping and sequence‑based grouping

Skills & Experience

Deep understanding of machine learning approaches for protein design and biological data analysis

Proven experience implementing bioinformatics tools for managing and analyzing large datasets (e.g., NGS, antibody libraries)

Proficient in Python or R, with experience using libraries like Biopython and PyMOL

Skilled in DNA and RNA sequencing data analysis

Familiarity with molecular modeling tools such as Rosetta, Schrodinger, or MOE

Strong background in antibody engineering, including liability remediation and biophysical optimization

Excellent communicator and collaborator, comfortable in cross‑functional teams

Adaptable and effective in a fast‑paced, small‑team environment

Qualifications

Ph.D. in Bioinformatics, Computational Biology, Statistics, or Biological Sciences with 0–5 years of experience

MS in a relevant field with 10–15 years of experience and demonstrated expertise

Equal Employment Opportunity / EEO Statement Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law.

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