Third Rock Ventures
Director of Bioanalytical Development, Stealth Company
Third Rock Ventures, San Francisco, California, United States, 94199
Director of Bioanalytical Development, Stealth Company
Seeking those who dare to achieve what others think is impossible
We are a fast-growing biotechnology company developing innovative antibody-based therapeutics. A well‑funded Third Rock Ventures Stealth Mode company is seeking a Director to lead strategy and execution for bioanalytical sciences across our pipeline. Reporting to the CSO, this role will support non‑clinical development and regulatory submissions. The Director ofanalytical Development will manage work through CROs, including identification, qualification, and oversight of external partners. A critical responsibility will be contributing to and ensuring high‑quality data to enable successful regulatory filings.
This is a highly collaborative, hands‑on role in a dynamic biotech environment, requiring scientific depth, operational agility, and the ability to thrive in a fast‑paced setting.
This role can be located in San Francisco or Boston and will work closely across these locations as well as with our Shanghai‑based team.
Key Responsibilities Strategic and Scientific Leadership
Define and implement bioanalytical strategies and ensure alignment with pipeline priorities and business needs.
Serve as the subject matter expert guiding assay design, method development, and data interpretation.
Champion the adoption of cutting‑edge technologies and methodologies in bioanalysis.
External Partner Management
Identify, validate, and select CROs and external partners for bioanalytical studies.
Oversee CRO activities to ensure compliance with timelines, budgets, quality standards and efficient data transfer.
Build strong relationships with external partners and monitor performance metrics.
Data Oversight
Ensure the timely delivery of high‑quality, scientifically sound bioanalytical data and oversee the integration of complex datasets.
Guarantee all bioanalytical studies and operations comply with global regulatory standards.
Scientific & Regulatory Contributions
Design, validate and implement bioanalytical assays supporting PK, PD, ADA and biomarker assays for preclinical studies.
Author and review regulatory documents and reports, such as those for IND filings.
Cross‑Functional Collaboration
Work across functions to align bioanalytical strategies with program goals.
Provide scientific input to project teams and contribute to key program decisions.
Qualifications
Ph.D. or equivalent in Pharmacology, Biochemistry, Immunology, or related discipline.
10+ years of experience in bioanalytical sciences within biotech or biopharma, with a focus on biologics or antibodies.
Proven expertise in biomarkers, PK/PD, and translational science.
Strong understanding of GLP requirements and regulatory expectations for IND submissions.
Demonstrated success in managing CROs and external consultants.
Excellent communication and leadership skills with ability to influence cross‑functional teams.
Preferred Experience
Experience with peptides or antibody‑drug conjugates (ADCs).
Expertise in obesity or cardiovascular metabolism research.
Prior authorship or significant contribution to IND submissions.
Familiarity with all relevant bioanalytical platforms.
Ability to operate effectively in a small, entrepreneurial biotech environment.
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This is a highly collaborative, hands‑on role in a dynamic biotech environment, requiring scientific depth, operational agility, and the ability to thrive in a fast‑paced setting.
This role can be located in San Francisco or Boston and will work closely across these locations as well as with our Shanghai‑based team.
Key Responsibilities Strategic and Scientific Leadership
Define and implement bioanalytical strategies and ensure alignment with pipeline priorities and business needs.
Serve as the subject matter expert guiding assay design, method development, and data interpretation.
Champion the adoption of cutting‑edge technologies and methodologies in bioanalysis.
External Partner Management
Identify, validate, and select CROs and external partners for bioanalytical studies.
Oversee CRO activities to ensure compliance with timelines, budgets, quality standards and efficient data transfer.
Build strong relationships with external partners and monitor performance metrics.
Data Oversight
Ensure the timely delivery of high‑quality, scientifically sound bioanalytical data and oversee the integration of complex datasets.
Guarantee all bioanalytical studies and operations comply with global regulatory standards.
Scientific & Regulatory Contributions
Design, validate and implement bioanalytical assays supporting PK, PD, ADA and biomarker assays for preclinical studies.
Author and review regulatory documents and reports, such as those for IND filings.
Cross‑Functional Collaboration
Work across functions to align bioanalytical strategies with program goals.
Provide scientific input to project teams and contribute to key program decisions.
Qualifications
Ph.D. or equivalent in Pharmacology, Biochemistry, Immunology, or related discipline.
10+ years of experience in bioanalytical sciences within biotech or biopharma, with a focus on biologics or antibodies.
Proven expertise in biomarkers, PK/PD, and translational science.
Strong understanding of GLP requirements and regulatory expectations for IND submissions.
Demonstrated success in managing CROs and external consultants.
Excellent communication and leadership skills with ability to influence cross‑functional teams.
Preferred Experience
Experience with peptides or antibody‑drug conjugates (ADCs).
Expertise in obesity or cardiovascular metabolism research.
Prior authorship or significant contribution to IND submissions.
Familiarity with all relevant bioanalytical platforms.
Ability to operate effectively in a small, entrepreneurial biotech environment.
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