GlaxoSmithKline
Principal Scientist, Translational Virology
GlaxoSmithKline, Cambridge, Massachusetts, us, 02140
Principal Scientist, GSK Vaccines – Translational Virology
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
We are looking for a highly collaborative, innovative virologist with experience in 3-dimensional (3D) cellular and in vivo translational models who can contribute to multiple projects and help advance a wide variety of viral vaccine candidates through preclinical development.
Key Responsibilities
Develop in-house 3D culture models containing multiple cell types, including immune cells
Implement and conduct in-house in vitro and in vivo virus challenge studies
Provide scientific expertise in the areas of cellular and immune responses to virus infection, vaccine mechanism of action, and development of assays to evaluate those responses.
Write protocols, procedures and work instructions to support assays
Train and mentor junior lab personnel
Communicate results orally or written internally or externally at conferences
Provide effective and inspiring leadership with an enterprise mindset, to enable collaboration with scientists across multiple functions, including key scientific stakeholders internally and externally
Independently write specific technical sections of internal and external reports and contribute to scientific papers
Basic Qualifications
PhD degree in life sciences with at least 3 years of postdoctoral or industry experience, or Master’s degree with at least 6 years’ experience in cellular biology and in vivo pharmacology
Three or more years of experience with in vivo virus challenge models and virological analyses
Three or more years of experience in 3D cellular models
Three or more years’ experience in molecular biology and immunology assays
Preferred Qualifications
Prior experience in virus-host interactions and/or vaccinology
Experience in model qualification and validation
Detailed knowledge in immunology and cellular biology as it applies to vaccines or related field
Basic skills in statistical analysis
Strong track‑record of scientific publications in peer‑reviewed journals
Ability to work and lead as part of a matrixed team
To be successful in the role, this person must
Have practical knowledge in a wide variety of virology, immunology, and cell culture techniques as well as working with animal and human biological samples
Demonstrate a comprehensive understanding of IACUC standards and practices related to animal welfare
Design and conduct detailed in vitro and in vivo studies with project‑directing deliverables
Exhibit a willingness to spend ~75% of time in the research laboratory
Understand, interpret, and communicate complex scientific data to determine next steps
Be a self‑starter able to handle multiple projects concurrently
Possess a good balance of creativity and analytical thinking faculties.
Display an ability to be productive and successful in an intense work environment as a Team Player
We are hiring in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA. The annual base salary for new hires in this position ranges $113,025 to $188,375, taking into account work location, skills, experience, education level, and market rate. In addition, this position offers an annual bonus and eligibility to participate in our share‑based long‑term incentive program. Benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK? Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the https://www.gsk.com/en-gb/careers/how-we-hire/frequently-asked-questions/ where you will find answers to multiple questions we receive.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies: GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/.
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We are looking for a highly collaborative, innovative virologist with experience in 3-dimensional (3D) cellular and in vivo translational models who can contribute to multiple projects and help advance a wide variety of viral vaccine candidates through preclinical development.
Key Responsibilities
Develop in-house 3D culture models containing multiple cell types, including immune cells
Implement and conduct in-house in vitro and in vivo virus challenge studies
Provide scientific expertise in the areas of cellular and immune responses to virus infection, vaccine mechanism of action, and development of assays to evaluate those responses.
Write protocols, procedures and work instructions to support assays
Train and mentor junior lab personnel
Communicate results orally or written internally or externally at conferences
Provide effective and inspiring leadership with an enterprise mindset, to enable collaboration with scientists across multiple functions, including key scientific stakeholders internally and externally
Independently write specific technical sections of internal and external reports and contribute to scientific papers
Basic Qualifications
PhD degree in life sciences with at least 3 years of postdoctoral or industry experience, or Master’s degree with at least 6 years’ experience in cellular biology and in vivo pharmacology
Three or more years of experience with in vivo virus challenge models and virological analyses
Three or more years of experience in 3D cellular models
Three or more years’ experience in molecular biology and immunology assays
Preferred Qualifications
Prior experience in virus-host interactions and/or vaccinology
Experience in model qualification and validation
Detailed knowledge in immunology and cellular biology as it applies to vaccines or related field
Basic skills in statistical analysis
Strong track‑record of scientific publications in peer‑reviewed journals
Ability to work and lead as part of a matrixed team
To be successful in the role, this person must
Have practical knowledge in a wide variety of virology, immunology, and cell culture techniques as well as working with animal and human biological samples
Demonstrate a comprehensive understanding of IACUC standards and practices related to animal welfare
Design and conduct detailed in vitro and in vivo studies with project‑directing deliverables
Exhibit a willingness to spend ~75% of time in the research laboratory
Understand, interpret, and communicate complex scientific data to determine next steps
Be a self‑starter able to handle multiple projects concurrently
Possess a good balance of creativity and analytical thinking faculties.
Display an ability to be productive and successful in an intense work environment as a Team Player
We are hiring in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA. The annual base salary for new hires in this position ranges $113,025 to $188,375, taking into account work location, skills, experience, education level, and market rate. In addition, this position offers an annual bonus and eligibility to participate in our share‑based long‑term incentive program. Benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK? Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the https://www.gsk.com/en-gb/careers/how-we-hire/frequently-asked-questions/ where you will find answers to multiple questions we receive.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies: GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/.
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