Tissue Connect Systems
Principal Systems Engineer - Healthcare RCM Platform
Tissue Connect Systems, New York, New York, us, 10261
Principal Systems Engineer – Healthcare RCM Platform
Location:
New York City (Remote to In-Person)
Full Time
Company:
TissueConnect Systems
About Us
TissueConnect Systems is an emerging leader in AI‑driven medical imaging solutions for orthopedic care. Founded by a team of orthopedic spine surgeons and medical students from the Hospital for Special Surgery, the world’s best orthopedic hospital, our mission is to transform patient care by developing quantitative imaging biomarkers to inform treatment approaches for a broad spectrum of musculoskeletal disease and predict associated outcomes. We combine cutting‑edge computer vision, medical image analysis, and machine learning to unlock new insights from MRI imaging, one of the most widely obtained modalities of medical imaging, accelerating the translation of novel imaging biomarkers from research into clinical practice.
The Role
We are now expanding into a next‑generation revenue cycle and EDI platform, MASIV, to connect our imaging technology natively into clinical and billing environments. MASIV enables seamless ingestion of patient demographics and imaging, insurance eligibility checks, claims routing, remittance automation, and enterprise data pipelines at scale. To build this, we are hiring a
Systems Engineer / Azure Architect
who will help build the cloud architecture of MASIV from the ground up.
You will build and scale MASIV — a HIPAA‑compliant, Azure‑native RCM system supporting X12 EDI flows, FHIR interoperability, clearinghouse integrations, claim adjudication, and provider billing.
You will collaborate with:
Our ML / computer vision team
Internal clinical product team
Provider partners and EHR vendors
This role is ideal for a builder who thrives in fast‑paced environments and wants to make a tangible impact by bringing real‑world AI applications to life.
Responsibilities You will architect, build, and deploy critical MASIV subsystems, including:
Ingest X12 claim files (837P/837I, 835, 276/277)
Implement Logic Apps workflows with Integration Accounts & X12 schemas
Convert between X12 and FHIR
Clearinghouse & Provider Connectivity
Build infrastructure to exchange claims, remittances, and claim status
Integrate with technical clearinghouses (e.g. stedi.com or equivalent)
Implement a multi‑tenant environment balancing isolation vs cost scalability
Enforce HIPAA‑grade boundary control
Data Engineering for Billing + Clinical
Render EDI and clinical data into a medallion‑style lakehouse
Manage ingestion pipelines for real‑time and batch
Payments
Design and implement secure, scalable payment systems on Microsoft Azure leveraging payment card tokenization, ensuring full adherence to applicable PCI‑DSS standards while managing compliance scope.
Serve as the subject matter expert for operations at the nexus of PCI‑DSS and HIPAA compliance within the Azure environment, developing and maintaining robust security protocols, including network segmentation, encryption, and secure access management for the Cardholder Data Environment (CDE).
Collaborate with cross‑functional development and operations teams, providing architectural guidance and creating comprehensive documentation to support all compliance efforts, security policies, and operational procedures for internal governance and external auditors.
Integrate real‑time eligibility (270/271) to support accurate pre‑service estimates and coverage validation.
Implement patient responsibility and adjudication workflows aligned with payer rules, secondary billing, and remittance outcomes.
Support claim attachment and supporting documentation flows, including payer‑specific routing, barcoded cover sheets, and templated submission requirements.
Qualifications
Bachelor’s, Master’s, or PhD in Computer Science, Biomedical Engineering, Electrical Engineering, or related field.
Azure Solutions Architect Expert certification. Additional Azure certifications a plus.
Healthcare IT Experience: Prior experience in healthcare IT, including familiarity with EMR/EHR systems integration. Experience with Epic integration is a plus.
Deep Azure experience across:
Power BI
Logic Apps + Integration Accounts (X12, HL7v2)
Power Platform
Health Data Services: Demonstrated experience with Azure Health Data Services, including designing, implementing, and optimizing solutions
FHIR store
AHDS security model
Role and identity isolation
Liquid templates & format conversion
Data Architecture: Solid understanding of data architecture principles, including cloud computing and proficiency in Azure data services like Azure Data Lake Storage, Synapse Analytics or Databricks (Spark), and data modeling software.
Compliance & Security: Expertise in navigating HIPAA/HITECH and implementing secure data solutions. Experience with tools like Microsoft Purview and Microsoft Priva for compliance is a plus.
Data Integration & ETL: Experience designing and implementing data pipelines, ETL processes, integrations with systems like EMRs (especially Epic) and HIEs, claim ingestion / clearinghouse APIs, and X12 message flows.
API Development: Experience in designing and building secure APIs for data exchange and for line‑of‑business applications.
Cloud Security Frameworks: Familiarity with cloud security frameworks and tools like Azure Security Center and Azure Sentinel.
Infrastructure as Code (IaC): Experience with tools like Terraform, Bicep/ARM templates, and PowerShell for automating deployments.
Soft Skills: Strong communication and stakeholder management skills are crucial, particularly when collaborating with clinical, operational, and executive teams, as well as mentoring junior engineers.
Why Join Us? At TissueConnect Systems, you’ll be part of a mission‑driven team working at the frontier of medical AI. You will have the opportunity to:
Contribute to technology that could redefine clinical management of musculoskeletal health and diseases.
Work with a diverse and inclusive multidisciplinary team of engineers and clinicians.
Grow your skills in a dynamic, fast‑moving startup environment.
Location Remote (U.S.) temporarily, but able to transition to in‑person work in New York City in approximately 6 months.
Compensation Highly competitive salary + equity + benefits, commensurate with experience. If you’re excited about our mission, we want to hear from you.
The base salary for this role is
$200,000 – 260,000.
Where you land within the range will reflect your skills and experience, while keeping team parity in mind and leaving room for future growth.
How to Apply If you’re excited to help shape the future of medical AI and revenue cycle management, send your resume and a brief introduction to nathooi@tissueconnect.ai (Isaac) and finosk@tissueconnect.ai (Kyle), two of our cofounders.
Referrals increase your chances of interviewing at TissueConnect Systems by 2x.
#J-18808-Ljbffr
New York City (Remote to In-Person)
Full Time
Company:
TissueConnect Systems
About Us
TissueConnect Systems is an emerging leader in AI‑driven medical imaging solutions for orthopedic care. Founded by a team of orthopedic spine surgeons and medical students from the Hospital for Special Surgery, the world’s best orthopedic hospital, our mission is to transform patient care by developing quantitative imaging biomarkers to inform treatment approaches for a broad spectrum of musculoskeletal disease and predict associated outcomes. We combine cutting‑edge computer vision, medical image analysis, and machine learning to unlock new insights from MRI imaging, one of the most widely obtained modalities of medical imaging, accelerating the translation of novel imaging biomarkers from research into clinical practice.
The Role
We are now expanding into a next‑generation revenue cycle and EDI platform, MASIV, to connect our imaging technology natively into clinical and billing environments. MASIV enables seamless ingestion of patient demographics and imaging, insurance eligibility checks, claims routing, remittance automation, and enterprise data pipelines at scale. To build this, we are hiring a
Systems Engineer / Azure Architect
who will help build the cloud architecture of MASIV from the ground up.
You will build and scale MASIV — a HIPAA‑compliant, Azure‑native RCM system supporting X12 EDI flows, FHIR interoperability, clearinghouse integrations, claim adjudication, and provider billing.
You will collaborate with:
Our ML / computer vision team
Internal clinical product team
Provider partners and EHR vendors
This role is ideal for a builder who thrives in fast‑paced environments and wants to make a tangible impact by bringing real‑world AI applications to life.
Responsibilities You will architect, build, and deploy critical MASIV subsystems, including:
Ingest X12 claim files (837P/837I, 835, 276/277)
Implement Logic Apps workflows with Integration Accounts & X12 schemas
Convert between X12 and FHIR
Clearinghouse & Provider Connectivity
Build infrastructure to exchange claims, remittances, and claim status
Integrate with technical clearinghouses (e.g. stedi.com or equivalent)
Implement a multi‑tenant environment balancing isolation vs cost scalability
Enforce HIPAA‑grade boundary control
Data Engineering for Billing + Clinical
Render EDI and clinical data into a medallion‑style lakehouse
Manage ingestion pipelines for real‑time and batch
Payments
Design and implement secure, scalable payment systems on Microsoft Azure leveraging payment card tokenization, ensuring full adherence to applicable PCI‑DSS standards while managing compliance scope.
Serve as the subject matter expert for operations at the nexus of PCI‑DSS and HIPAA compliance within the Azure environment, developing and maintaining robust security protocols, including network segmentation, encryption, and secure access management for the Cardholder Data Environment (CDE).
Collaborate with cross‑functional development and operations teams, providing architectural guidance and creating comprehensive documentation to support all compliance efforts, security policies, and operational procedures for internal governance and external auditors.
Integrate real‑time eligibility (270/271) to support accurate pre‑service estimates and coverage validation.
Implement patient responsibility and adjudication workflows aligned with payer rules, secondary billing, and remittance outcomes.
Support claim attachment and supporting documentation flows, including payer‑specific routing, barcoded cover sheets, and templated submission requirements.
Qualifications
Bachelor’s, Master’s, or PhD in Computer Science, Biomedical Engineering, Electrical Engineering, or related field.
Azure Solutions Architect Expert certification. Additional Azure certifications a plus.
Healthcare IT Experience: Prior experience in healthcare IT, including familiarity with EMR/EHR systems integration. Experience with Epic integration is a plus.
Deep Azure experience across:
Power BI
Logic Apps + Integration Accounts (X12, HL7v2)
Power Platform
Health Data Services: Demonstrated experience with Azure Health Data Services, including designing, implementing, and optimizing solutions
FHIR store
AHDS security model
Role and identity isolation
Liquid templates & format conversion
Data Architecture: Solid understanding of data architecture principles, including cloud computing and proficiency in Azure data services like Azure Data Lake Storage, Synapse Analytics or Databricks (Spark), and data modeling software.
Compliance & Security: Expertise in navigating HIPAA/HITECH and implementing secure data solutions. Experience with tools like Microsoft Purview and Microsoft Priva for compliance is a plus.
Data Integration & ETL: Experience designing and implementing data pipelines, ETL processes, integrations with systems like EMRs (especially Epic) and HIEs, claim ingestion / clearinghouse APIs, and X12 message flows.
API Development: Experience in designing and building secure APIs for data exchange and for line‑of‑business applications.
Cloud Security Frameworks: Familiarity with cloud security frameworks and tools like Azure Security Center and Azure Sentinel.
Infrastructure as Code (IaC): Experience with tools like Terraform, Bicep/ARM templates, and PowerShell for automating deployments.
Soft Skills: Strong communication and stakeholder management skills are crucial, particularly when collaborating with clinical, operational, and executive teams, as well as mentoring junior engineers.
Why Join Us? At TissueConnect Systems, you’ll be part of a mission‑driven team working at the frontier of medical AI. You will have the opportunity to:
Contribute to technology that could redefine clinical management of musculoskeletal health and diseases.
Work with a diverse and inclusive multidisciplinary team of engineers and clinicians.
Grow your skills in a dynamic, fast‑moving startup environment.
Location Remote (U.S.) temporarily, but able to transition to in‑person work in New York City in approximately 6 months.
Compensation Highly competitive salary + equity + benefits, commensurate with experience. If you’re excited about our mission, we want to hear from you.
The base salary for this role is
$200,000 – 260,000.
Where you land within the range will reflect your skills and experience, while keeping team parity in mind and leaving room for future growth.
How to Apply If you’re excited to help shape the future of medical AI and revenue cycle management, send your resume and a brief introduction to nathooi@tissueconnect.ai (Isaac) and finosk@tissueconnect.ai (Kyle), two of our cofounders.
Referrals increase your chances of interviewing at TissueConnect Systems by 2x.
#J-18808-Ljbffr