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Nexify Infosystems

Senior Data Manager/ Data architect with DICOM

Nexify Infosystems, San Francisco, California, United States, 94199

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Senior Data Manager/ Data architect with DICOM Job Title:

Senior Data Manager/ Data Architect with DICOM

Duration : 12+ Months

Job Description :

Image Curation and Data products team transforms biomedical imaging data from clinical trials and RWD, by applying the tools and workflows to deliver high quality, FAIR imaging data sets enabling imaging data scientists to discover and utilize for exploratory use to algorithm development.

Key Responsibilities:

Imaging Data Pipeline delivery : Design, implement and maintain automated pipelines for onboarding, verifying, transforming and curating biomedical imaging data from clinical trials and real world data sources, for therapeutic areas, Oncology, Neurology, Ophthalmology covering all image file formats.

Data Quality and Integrity : Develop and implement solutions to detect and correct anomalies and inconsistencies, to achieve highest data quality of the imaging data set, per industry standards DICOM, and internal specifications like FFS, RTS, GDSR, etc. Ensure de-identification, PHI/PII controls, and image specific QC checks are implemented at scale.

Data Analysis and integration : Integrate ML and AI assisted tools in the pipelines for inline image analysis, classifications, segmentations, to extract and enrich metadata for various analyses, optimize performance etc..

Image Data Management : Build and maintain large scale catalogs of curated imaging data sets enhancing FAIR principles, and providing easy to discover and access imaging data assets.

Compliance and Controls : Ensure applicable compliance and privacy controls are followed as required GXP, CSV validations.

Collaboration : Working closely with Image scientists, data scientists, clinops, and biomarker research teams, supporting data needs for various primary and secondary endpoint analyses.

External collaboration : Work with external partners e.g. CROs in ensuring the imaging data received conforms to the established agreements and quality standards and complete.

Lead to the delivery team to ensure timely delivery of product backlog / features

Participate with the team and lead various agile ceremonies throughout the planning and execution. Ideal candidate would have, (multiple competencies from list below);

Qualifications:

Worked with medical imaging data and platforms , PACS, VNAs etc.

Worked with imaging Radiology data e.g. CT, PET, MRI, nifti and Ophtha imaging OCT, FA,CFP etc.

Good understanding of DICOM standard, structure, metadata parsing, tags, multi-frame images

Worked with Clinical information data standards like, SDTM, ADaM

Data integration across diverse data sources, e.g. imaging data with tabular clinical data

De-identifi cation methodologies, PHI/PII detection and privacy controls

Good understanding of GXP and CSV validation frameworks

Proficient in Python, its libraries : pandas , pydicom, SimpleITK , dicom-numpy, dcm2niix

Hands on experience with ETL/ELT involving large medical imaging datasets

Apache Airfl ow, Spark, Talend or similar orchestration of complex workflows.

Proficiency with SQL and noSql , and image meta data stores. (PostgreSQL, Mongo Etc)

Practical experience with AWS infrastructure Data services , e.g. RDS, Athena, Glue , EC2 Lambda, S3 ….

Familiar with EKS, Docker , and HPC

Experience in data analysis and report generation, e.g Tibco, Tableau, AWS Quicksite etc

Good knowledge of Git, Gitlab and DevOps tools like Jenkins, Terraform

Familiar with using ML workflows for Computer Vision tasks like segmentation, classifi cation, etc..

Nice to have: implemented solutions on NLP and GenAI 18.

Worked with cross functional global teams in a dynamic Agile environment

Lead and mentor agile team members.

Has 10+ years of experience with data platforms, analysis and insights

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