University of Michigan-Flint School of Management
Research Lab Specialist Senior - Lab Manager (Intermediate Underfill)
University of Michigan-Flint School of Management, Ann Arbor, Michigan, us, 48113
Research Lab Specialist Senior - Lab Manager (Intermediate Underfill)
Location: Ann Arbor Campus, Ann Arbor, MI
Job Summary: An exciting opportunity has been created for an experienced researcher to join the Alumkal Laboratory at the U of M Division of Heme-Onc and the Rogel Cancer Center in Ann Arbor, MI. The individual will join as a Research Lab Specialist Senior and work directly with Dr. Joshi Alumkal, Leader of the U of M Prostate/Genitourinary Oncology Cancer Section. They will be an integral member of a research team whose focus is epigenetics and drug resistance in prostate cancer, and will be responsible for managing all phases of complex in vivo research projects, including project design and procedure. This individual must be proficient in rodent surgery, including xenograft tumor implantation in mice.
Our laboratory focuses on identifying mechanisms by which key chromatin modifying enzymes and chromatin readers drive transcription of pathways that promote treatment resistance. We use genomics studies in prostate cancer clinical samples and prostate cancer cell line model systems and functional studies to understand this process. Our goal is to develop new, targeted treatment strategies for men with advanced prostate cancer.
Why Join Michigan Medicine? Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U‑M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world‑class institution. Work at Michigan Medicine and become a victor for the greater good.
Benefits
Excellent medical, dental and vision coverage effective on your very first day
2:1 Match on retirement savings
Responsibilities
Manage all phases of lab’s complex in vivo studies, coordinate the development of research goals and project design.
Maintain the mouse breeding colony; perform mouse tumor growth experiments with xenograft implantation surgery; supervise and provide technical assistance to lab personnel performing drug injections, drug gavage, and tumor measurements.
Responsible for day‑to‑day operations of the lab, including sample coordination, processing, storage and inventory management, and shipping for some studies.
Order and stock supplies, maintain equipment, oversee regulatory approvals (IACUC, IRB, IBC) related to projects.
Perform additional duties such as writing research proposals, co‑authoring publications, cell culture, molecular biology techniques including DNA/RNA/protein extraction, QPCR, and Western blots.
Required Qualifications
Bachelor’s degree required and 4-5 years experience for Research Lab Specialist Intermediate.
Bachelor’s degree required and 5-6 years experience for Research Lab Specialist Senior.
Strong organizational and multi‑tasking skills.
Excellent teamwork and communication skills.
Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.
Responsible for ensuring lab documentation is up to date for safety inspections.
Ability and willingness to learn and implement novel experimental techniques.
Proficient with computers running Windows and PC applications (e.g., MS Excel, Word and PowerPoint).
Desired Qualifications
Master’s Degree or Doctoral Degree desired but not required.
Previous lab management skills strongly preferred.
Prior experience with writing and maintaining IACUC and IBC protocols strongly preferred.
Proficiency with mammalian cell culture and with molecular biology techniques such as RT‑PCR, western blotting, cloning, and reporter gene analysis preferred.
Rodent handling experience, including injection and/or gavage treatment, preferred.
Modes of Work Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.
Underfill Statement This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Background Screening Michigan Medicine conducts background screening and pre‑employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third‑party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre‑employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U‑M campuses.
Application Deadline Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
EEO Statement The University of Michigan is an equal employment opportunity employer.
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Job Summary: An exciting opportunity has been created for an experienced researcher to join the Alumkal Laboratory at the U of M Division of Heme-Onc and the Rogel Cancer Center in Ann Arbor, MI. The individual will join as a Research Lab Specialist Senior and work directly with Dr. Joshi Alumkal, Leader of the U of M Prostate/Genitourinary Oncology Cancer Section. They will be an integral member of a research team whose focus is epigenetics and drug resistance in prostate cancer, and will be responsible for managing all phases of complex in vivo research projects, including project design and procedure. This individual must be proficient in rodent surgery, including xenograft tumor implantation in mice.
Our laboratory focuses on identifying mechanisms by which key chromatin modifying enzymes and chromatin readers drive transcription of pathways that promote treatment resistance. We use genomics studies in prostate cancer clinical samples and prostate cancer cell line model systems and functional studies to understand this process. Our goal is to develop new, targeted treatment strategies for men with advanced prostate cancer.
Why Join Michigan Medicine? Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U‑M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world‑class institution. Work at Michigan Medicine and become a victor for the greater good.
Benefits
Excellent medical, dental and vision coverage effective on your very first day
2:1 Match on retirement savings
Responsibilities
Manage all phases of lab’s complex in vivo studies, coordinate the development of research goals and project design.
Maintain the mouse breeding colony; perform mouse tumor growth experiments with xenograft implantation surgery; supervise and provide technical assistance to lab personnel performing drug injections, drug gavage, and tumor measurements.
Responsible for day‑to‑day operations of the lab, including sample coordination, processing, storage and inventory management, and shipping for some studies.
Order and stock supplies, maintain equipment, oversee regulatory approvals (IACUC, IRB, IBC) related to projects.
Perform additional duties such as writing research proposals, co‑authoring publications, cell culture, molecular biology techniques including DNA/RNA/protein extraction, QPCR, and Western blots.
Required Qualifications
Bachelor’s degree required and 4-5 years experience for Research Lab Specialist Intermediate.
Bachelor’s degree required and 5-6 years experience for Research Lab Specialist Senior.
Strong organizational and multi‑tasking skills.
Excellent teamwork and communication skills.
Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.
Responsible for ensuring lab documentation is up to date for safety inspections.
Ability and willingness to learn and implement novel experimental techniques.
Proficient with computers running Windows and PC applications (e.g., MS Excel, Word and PowerPoint).
Desired Qualifications
Master’s Degree or Doctoral Degree desired but not required.
Previous lab management skills strongly preferred.
Prior experience with writing and maintaining IACUC and IBC protocols strongly preferred.
Proficiency with mammalian cell culture and with molecular biology techniques such as RT‑PCR, western blotting, cloning, and reporter gene analysis preferred.
Rodent handling experience, including injection and/or gavage treatment, preferred.
Modes of Work Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.
Underfill Statement This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Background Screening Michigan Medicine conducts background screening and pre‑employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third‑party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre‑employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U‑M campuses.
Application Deadline Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
EEO Statement The University of Michigan is an equal employment opportunity employer.
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