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Amgen

Scientist - LC-MS Bioanalytical

Amgen, Thousand Oaks, California, United States, 91362

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Overview Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award‑winning culture is collaborative, innovative, and science based.

Scientist - LC‑MS Bioanalytical What You Will Do In this vital role, you will support the design, development, validation, and implementation of robust LC‑MS/MS bioanalytical methods for a wide range of therapeutic modalities—including small molecules, oligonucleotides, proteins, and other complex molecular entities—to enable GLP preclinical and regulated clinical studies. The position is lab‑based, with a significant emphasis on data management/fidelity, report generation, effective time management, communication, and data presentation.

Perform quantitative bioanalytical experiments and organize data and results, including planning and running LC‑MS/MS bioanalysis and preparing and analyzing biological samples

Develop and implement LC‑MS/MS bioanalytical methods with quick turnaround times

Conduct small and large molecule bioanalysis in non‑clinical and clinical samples from various matrices (plasma, urine, CSF, tissues)

Perform biological sample extraction using protein crash (PPT), SPE, LLE, and/or affinity capture methodologies

Generate complete, accurate, and concise documentation using electronic systems and laboratory notebook

Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines

Author study reports, standard operating procedures, analytical methods, memos, and other regulatory‑compliant documents

Communicate bioanalytical data to key discovery and development teams, contribute to scientific publications, and present at professional meetings

Comply with safety guidelines and site‑specific procedures, including training completion, record maintenance, laboratory documentation, and SOP adherence

Perform general laboratory housekeeping activities and operational support as needed, including QC of reports

What We Expect Of You We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a dedicated scientist with the following qualifications.

Basic Qualifications

Doctorate degree (PhD, PharmD, or MD) with relevant post‑doc where applicable and 1–3 years of relevant industrial or postdoctoral experience

Or Master’s degree and 5 years of relevant industrial/technical experience

Or Bachelor’s degree and 7 years of relevant industrial/technical experience

Preferred Qualifications

Prior experience in CRO or pharma/biotech strongly desired

Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS

Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation and/or micro‑sampling

Prior GLP and GCP experience

Demonstrated expertise in working with a variety of sample types (e.g., blood, plasma, serum, tissues, cerebrospinal fluid) and employing diverse sample preparation techniques (e.g., SPE, LLE, immunocapture) to support analysis of different therapeutic modalities, including small and large molecules by LC‑MS

Prior experience in bioanalytical (regulated) assay execution and transfer to CROs

Must be willing to work in a fast‑paced, multi‑project environment with high workload demands, and consistently deliver high‑quality results within established timelines

Demonstrated ability to resolve scientific challenges efficiently and prioritize effectively

Excellent scientific problem‑solving skills

Excellent project and time management abilities

Ability to work collaboratively with internal and external stakeholders

Supervisory and mentoring experience in a lab‑based setting

What You Can Expect Of Us In addition to the base salary, Amgen offers a Total Rewards Plan, comprising health and welfare plans for staff and eligible dependents, financial plans, work/life balance, and career development opportunities. Benefits include:

A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan

Stock‑based long‑term incentives

Award‑winning time‑off plans

Flexible work models, including remote and hybrid work arrangements, where possible

Application Deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship Sponsorship for this role is not guaranteed.

Equal Opportunity Statement As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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