Vaxcyte, Inc
Associate Scientist II, Analytical Development
Vaxcyte, Inc, San Carlos, California, United States, 94071
Associate Scientist II, Analytical Development
Join our Mission to Protect Humankind!
Vaxcyte is a clinical‑stage vaccine innovation company engineering high‑fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well‑defined, and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re‑innovate the way vaccines are delivered.
AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness‑first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Summary: Vaxcyte is looking for an energetic and talented individual to join our Analytical Development team. Primary responsibility for the incumbent will be to support the developmental activities currently on going in the laboratory as assigned.
Essential Functions:
Assist in the design, execution and interpretation of experiments to analyze drug substances and intermediates such as proteins and carbohydrates including:
Microplate assays include enzymatic assays.
HPLC – Especially SEC and RP‑HPLC with experience in Chemstation.
CE and iCIEF – Especially with Protein Simple or PA‑800 systems.
Assist in analytical method development of new assays.
Keep accurate and detailed records of experiments.
Summarize data and communicate to analytical team.
Support daily lab operations, sample inventory and sample shipment.
Work within a team environment and provide support to further team objectives.
Complete any assigned tasks with high quality and in a timely manner.
Requirements:
BS in Chemistry, Analytical Chemistry preferred, Organic / Biochemistry considered, with 2+ years of relevant lab experience, or MS with 1+ years of experience. Other combinations of education and/or experience may be considered.
Ideal candidate will have a background in analytical chemistry principles and hands‑on experience with modern analytical instrumentations commonly used in the analysis and characterization of drug candidates. Candidates with other scientific disciplines may be considered based on relevant experience.
Experience in chemical and biological assays such as colorimetric/fluorometric microplate assays and HPLC.
Experience working with protein analysis – UV‑Vis, CE, Bradford etc.
Experience working with carbohydrate analysis and SEC‑MALS a plus.
Understanding of basic principles of analytical method development/validation/ qualification concepts.
Attention to detail and excellent skills in record keeping / documentation. Critical thinking and ability to analyze data.
Strong interpersonal skills: ability to communicate effectively both verbally and in written formats.
Ability to work under supervision and independently in a fast‑paced, cross‑functional environment and collaborate effectively with other team members. Eagerness and ability to learn and understand new concepts with ease.
Reports to:
Manager, Analytical Development
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range:
$105,000 – $124,000 (SF Bay Area). Salary ranges for non‑California locations may vary.
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
Voluntary Self-Identification of Disability Form CC-305 Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026
Why are you being asked to complete this form?
We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress toward this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
How do you know if you have a disability?
A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.
Disabilities include, but are not limited to:
Alcohol or other substance use disorder (not currently using drugs illegally)
Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
Blind or low vision
Cancer (past or present)
Cardiovascular or heart disease
Celiac disease
Cerebral palsy
Deaf or serious difficulty hearing
Diabetes
Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
Epilepsy or other seizure disorder
Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
Intellectual or developmental disability
Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
Missing limbs or partially missing limbs
Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
Partial or complete paralysis (any cause)
Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
Short stature (dwarfism)
Traumatic brain injury
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
#J-18808-Ljbffr
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re‑innovate the way vaccines are delivered.
AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness‑first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Summary: Vaxcyte is looking for an energetic and talented individual to join our Analytical Development team. Primary responsibility for the incumbent will be to support the developmental activities currently on going in the laboratory as assigned.
Essential Functions:
Assist in the design, execution and interpretation of experiments to analyze drug substances and intermediates such as proteins and carbohydrates including:
Microplate assays include enzymatic assays.
HPLC – Especially SEC and RP‑HPLC with experience in Chemstation.
CE and iCIEF – Especially with Protein Simple or PA‑800 systems.
Assist in analytical method development of new assays.
Keep accurate and detailed records of experiments.
Summarize data and communicate to analytical team.
Support daily lab operations, sample inventory and sample shipment.
Work within a team environment and provide support to further team objectives.
Complete any assigned tasks with high quality and in a timely manner.
Requirements:
BS in Chemistry, Analytical Chemistry preferred, Organic / Biochemistry considered, with 2+ years of relevant lab experience, or MS with 1+ years of experience. Other combinations of education and/or experience may be considered.
Ideal candidate will have a background in analytical chemistry principles and hands‑on experience with modern analytical instrumentations commonly used in the analysis and characterization of drug candidates. Candidates with other scientific disciplines may be considered based on relevant experience.
Experience in chemical and biological assays such as colorimetric/fluorometric microplate assays and HPLC.
Experience working with protein analysis – UV‑Vis, CE, Bradford etc.
Experience working with carbohydrate analysis and SEC‑MALS a plus.
Understanding of basic principles of analytical method development/validation/ qualification concepts.
Attention to detail and excellent skills in record keeping / documentation. Critical thinking and ability to analyze data.
Strong interpersonal skills: ability to communicate effectively both verbally and in written formats.
Ability to work under supervision and independently in a fast‑paced, cross‑functional environment and collaborate effectively with other team members. Eagerness and ability to learn and understand new concepts with ease.
Reports to:
Manager, Analytical Development
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range:
$105,000 – $124,000 (SF Bay Area). Salary ranges for non‑California locations may vary.
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
Voluntary Self-Identification of Disability Form CC-305 Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026
Why are you being asked to complete this form?
We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress toward this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
How do you know if you have a disability?
A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.
Disabilities include, but are not limited to:
Alcohol or other substance use disorder (not currently using drugs illegally)
Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
Blind or low vision
Cancer (past or present)
Cardiovascular or heart disease
Celiac disease
Cerebral palsy
Deaf or serious difficulty hearing
Diabetes
Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
Epilepsy or other seizure disorder
Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
Intellectual or developmental disability
Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
Missing limbs or partially missing limbs
Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
Partial or complete paralysis (any cause)
Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
Short stature (dwarfism)
Traumatic brain injury
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
#J-18808-Ljbffr