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Freenome Holdings, Inc

Senior Software Engineer

Freenome Holdings, Inc, California, Missouri, United States, 65018

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Our infrastructure team is a small but critical group where you will help set the culture and build the systems that allow us to move fast without breaking things. This is an opportunity to do meaningful engineering work that will directly save lives.

We value:

Rapid iteration and tight feedback loops

Continual improvement rather than disruption

Technical simplicity and elegance

A focus on the larger goals

Mutual respect and blameless postmortems

A culture of diversity and inclusion

As a Senior Software Engineer, you will help design, build, and maintain secure and scalable infrastructure across our cloud environments. You’ll contribute to projects that support our clinical lab systems, scientific computing pipelines, and regulated production workloads — while growing your technical leadership and deepening your infrastructure expertise.

This role is ideal for an engineer who is experienced with cloud platforms and Kubernetes, comfortable working independently, and ready to take ownership of well‑scoped systems or infrastructure components. Additionally, this role is Hybrid and will entail managing our onsite Nvidia infrastructure.

As an engineering‑forward biotech company, we apply modern engineering practices to build reliable, maintainable, scalable, and secure production systems for our clinical lab and Computational and Molecular Research Scientists.

The role reports to the Director, Cloud Infrastructure.

What you’ll do Execution

Design and implement cloud infrastructure components using Pulumi (Python)

Manage and maintain Kubernetes clusters (AKS, GKE), including node pools, ILBs, and autoscaling configurations

Define observability patterns and implement metrics, dashboards, and alerts in support of production reliability

Contribute to our CI/CD platforms, including build pipeline improvements, deployment strategies, and release automation

Participate in incident response and postmortem analysis for infrastructure‑related outages or events

Communication and Collaboration

Partner with team members, TPMs, and security stakeholders to deliver infrastructure that meets compliance and reliability requirements

Lead technical implementation of projects or initiatives within your scope

Perform thorough, constructive code reviews and help level up peers through pairing and design discussions

Communicate clearly with cross‑functional teams and represent infrastructure in collaborative settings

Culture

Model Freenome’s values and principles in your work and interactions

Promote a collaborative, respectful engineering culture with clear communication and inclusive practices

Actively contribute to documentation, playbooks, and engineering standards within the team

Help foster a strong team culture of accountability, learning, and psychological safety

Technical Leadership

Independently lead the delivery of projects or well‑bounded infrastructure systems

Provide mentorship to junior engineers and review designs within your domain

Know when to make architectural tradeoffs with guidance and justify design decisions based on long‑term impact

Help evolve our infrastructure practices and participate in team strategy discussions

Must haves

Bachelor's degree in Computer Science, Engineering, or equivalent work experience

Experience with NVIDIA DGX systems and NVIDIA software tech stack

5+ years of experience in software engineering roles (Python preferred), with at least 2 years focused on cloud infrastructure

Production experience with Kubernetes in cloud environments (e.g., AKS, GKE, or EKS)

Proficiency with Terraform, Pulumi, or similar IaC tools

Experience with CI/CD, including deployment automation and release strategies

Familiarity with cloud IAM, networking, and security best practices

Strong troubleshooting and root cause analysis skills in distributed systems

Demonstrated ability to work autonomously and own technical outcomes

Nice to haves

Experience supporting infrastructure in regulated environments (e.g., healthcare, biotech, financial)

Background in observability platforms such as Prometheus, Grafana, OpenTelemetry

Exposure to cost optimization, audit logging, or compliance automation in cloud platforms

Experience working with scientists, data engineers, or platform users in cross‑functional settings

Interest in mentorship, system design, and infrastructure patterns at scale

Experience with Microsoft Azure

Benefits and additional information The US target range of our base salary for new hires is $131,325 - $201,000. You will also be eligible to receive pre‑IPO equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page at freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal‑opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

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