BioSpace
Director, Head of Bioinformatics for Immunology
BioSpace, Cambridge, Massachusetts, us, 02140
Director, Head of Bioinformatics for Immunology
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Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit www.abbvie.com.
Job Description The role of Director, Head of Bioinformatics for Immunology in Quantitative Medicine and Genomics (QM&G) is pivotal for driving data‑driven insight for target identification and validation, biomarker discovery, clinical development, forward and reverse translation, therapeutic innovation, and manufacturing within the QM&G functional area and across R&D. This role is responsible for leading a distributed team that leverages cutting‑edge bioinformatics to derive novel insights for end‑to‑end drug discovery and development; while the position is focused primarily in Immunology there are also opportunities for cross‑collaboration in multiple therapeutic areas, including Aesthetics, Specialty Medicine, Biotherapeutics, and Manufacturing Science and Technology.
Key Responsibilities
Accelerate AbbVie’s drug discovery and development pipeline by establishing forward‑thinking informatics strategies and executing on results for multiple disease areas within Immunology.
Lead a dynamic team of bioinformaticians and data scientists, fostering a culture of high performance and professional growth.
Spearhead innovative computational systems biology initiatives to revolutionize the discovery of therapeutic targets.
Integrate insights from genetic, multi‑omics, and functional genomics data to drive innovation in therapy development.
Oversee the application of AI/ML methods in both discovery and clinical development, enabling reverse translation through cross‑sectional, multi‑modal clinical data analysis.
Optimize genetic medicine and biotherapeutics manufacturing capabilities through advanced computational insights and AI/ML applications.
Foster strong collaborations within the bioinformatics community and across R&D, clinical teams, and other departments to ensure bioinformatic and genetic insights are effectively integrated into AbbVie’s pipeline programs.
Lead partnerships with academic institutions, biotechnology companies, and technology providers to evaluate and integrate emerging technologies.
Qualifications
PhD in bioinformatics, statistics, mathematics, computer science, computational biology, genomics, or a related field with 8+ years of industry/academic experience; OR master’s degree with 15+ years of relevant experience.
Proven success managing, leading, and mentoring interdisciplinary teams in large‑scale research environments.
Extensive experience applying AI/ML techniques in drug discovery and development to drive innovation and therapeutic outcomes.
Deep expertise in transcriptomics and proteomics, encompassing bulk, single‑cell, and spatial approaches, and multi‑omic integration methodologies.
Proficient in genetic analysis techniques, including GWAS, QTL, genetic risk modeling, and multi‑omics integration with actionable insights.
Strong background in target identification, biomarker discovery, and clinical translation to enhance therapeutic development processes.
Demonstrated ability to collaborate cross‑functionally with clinical teams and translate complex computational findings into clinical insights.
Adept at articulating complex scientific concepts to non‑scientific stakeholders and executive leadership.
Additional Information
The compensation range described below is the range of possible base pay that the Company believes in good faith it will pay for this role at the time of this posting, based on the job grade. Individual compensation paid within this range will depend on many factors, including geographic location. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and a 401(k) to eligible employees.
This job is eligible to participate in our short‑term incentive programs.
Note: No amount of pay is considered wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or other compensation are at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only – to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html. US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable‑accommodations.html.
Seniority Level Director
Employment Type Full‑time
Job Function Other
Industries Internet News
#J-18808-Ljbffr
Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit www.abbvie.com.
Job Description The role of Director, Head of Bioinformatics for Immunology in Quantitative Medicine and Genomics (QM&G) is pivotal for driving data‑driven insight for target identification and validation, biomarker discovery, clinical development, forward and reverse translation, therapeutic innovation, and manufacturing within the QM&G functional area and across R&D. This role is responsible for leading a distributed team that leverages cutting‑edge bioinformatics to derive novel insights for end‑to‑end drug discovery and development; while the position is focused primarily in Immunology there are also opportunities for cross‑collaboration in multiple therapeutic areas, including Aesthetics, Specialty Medicine, Biotherapeutics, and Manufacturing Science and Technology.
Key Responsibilities
Accelerate AbbVie’s drug discovery and development pipeline by establishing forward‑thinking informatics strategies and executing on results for multiple disease areas within Immunology.
Lead a dynamic team of bioinformaticians and data scientists, fostering a culture of high performance and professional growth.
Spearhead innovative computational systems biology initiatives to revolutionize the discovery of therapeutic targets.
Integrate insights from genetic, multi‑omics, and functional genomics data to drive innovation in therapy development.
Oversee the application of AI/ML methods in both discovery and clinical development, enabling reverse translation through cross‑sectional, multi‑modal clinical data analysis.
Optimize genetic medicine and biotherapeutics manufacturing capabilities through advanced computational insights and AI/ML applications.
Foster strong collaborations within the bioinformatics community and across R&D, clinical teams, and other departments to ensure bioinformatic and genetic insights are effectively integrated into AbbVie’s pipeline programs.
Lead partnerships with academic institutions, biotechnology companies, and technology providers to evaluate and integrate emerging technologies.
Qualifications
PhD in bioinformatics, statistics, mathematics, computer science, computational biology, genomics, or a related field with 8+ years of industry/academic experience; OR master’s degree with 15+ years of relevant experience.
Proven success managing, leading, and mentoring interdisciplinary teams in large‑scale research environments.
Extensive experience applying AI/ML techniques in drug discovery and development to drive innovation and therapeutic outcomes.
Deep expertise in transcriptomics and proteomics, encompassing bulk, single‑cell, and spatial approaches, and multi‑omic integration methodologies.
Proficient in genetic analysis techniques, including GWAS, QTL, genetic risk modeling, and multi‑omics integration with actionable insights.
Strong background in target identification, biomarker discovery, and clinical translation to enhance therapeutic development processes.
Demonstrated ability to collaborate cross‑functionally with clinical teams and translate complex computational findings into clinical insights.
Adept at articulating complex scientific concepts to non‑scientific stakeholders and executive leadership.
Additional Information
The compensation range described below is the range of possible base pay that the Company believes in good faith it will pay for this role at the time of this posting, based on the job grade. Individual compensation paid within this range will depend on many factors, including geographic location. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and a 401(k) to eligible employees.
This job is eligible to participate in our short‑term incentive programs.
Note: No amount of pay is considered wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or other compensation are at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only – to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html. US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable‑accommodations.html.
Seniority Level Director
Employment Type Full‑time
Job Function Other
Industries Internet News
#J-18808-Ljbffr