Vir Biotechnology, Inc.
Associate Director, Clinical Operations
Vir Biotechnology, Inc., San Francisco, California, United States, 94199
Vir Biotechnology is a clinical‑stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical‑stage portfolio includes programs for chronic hepatitis delta and multiple dual‑masked T‑cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.
We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.
THE OPPORTUNITY
Vir Bio is looking for an Associate Director, Clinical Operations, to independently lead global and complex clinical trials. You will lead the Study Management Team, oversee clinical vendors and CRO(s), and be accountable for ensuring the successful execution and conduct of clinical trial(s). In this role you will directly manage a large, complex early‑phase oncology study, including vendor selection and management, protocol and study document development, feasibility/start‑up, maintenance, and closure. You will lead Clinical Operations, participate on SOP development groups, manage direct reports, and provide stakeholder management for cross‑functional teams. WHAT YOU'LL DO
Provide strategic input and leadership in study set‑up and execution of highly complex oncology clinical trials, supporting multiple trials. Establish and continuously monitor study timelines and budgets, promptly escalating significant risks or changes. Develop and manage study contracts, budgets and timelines. Author/review core study documents including protocol and Informed Consent Forms. Manage CRO, central lab, systems vendors, and ancillary vendors to ensure on‑target deliverables. Develop study plans and relevant study document templates for study teams. Support regulatory strategy and assess trial/program impact and RFIs from multiple countries. Lead RFP process, budget development, and study forecast/planning including timelines. Perform sponsor oversight site visits. Oversight of clinical monitoring activities, including monitoring trip report review and overall site management, ensuring compliance with GCP and applicable regulations, and tracking site performance metrics. Review monitoring trip reports and track resolution of all action items. Manage team with direct reports within therapeutic area. Serve as Clinical Operations lead on cross‑functional project teams and alliance teams. Stakeholder management with internal business partners, key opinion leaders, and external partners on clinical studies. WHO YOU ARE AND WHAT YOU BRING
Bachelor of Science degree (preferably in the life sciences). 10+ years of clinical development experience in the biotech/pharmaceutical industry. Extensive experience working on oncology clinical studies. Experience managing and leading clinical studies from early phase through late stage. Experience leading all stages of clinical trials, including start‑up, maintenance, and close‑out. Thorough understanding of FDA, EMEA, and ROW ICH and GCP guidelines, and cross‑functional clinical processes (data management, biostatistics, medical monitoring, drug safety, regulatory affairs). Experience with regulatory compliance audits and inspections. Experience directing and leading in a complex team environment. Ability to function at a high level when leading a group or managing day‑to‑day details when needed. Flexibility to travel domestically and internationally. WHO WE ARE AND WHAT WE OFFER
The expected salary range for this position is $176,500 to $246,500 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors. Vir Biotechnology’s compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full‑time employees receive a package that includes compensation, bonus and equity, as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non‑accrual paid time off, company shutdown for holidays, commuter benefits, childcare reimbursement, education reimbursement, 401(k) match, and lunch each day in the office. Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time. All employment decisions at Vir Biotechnology are based on legitimate, non‑discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics. This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment. Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees. For hires based in the United States, Vir Biotechnology participates in E‑Verify.
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Vir Bio is looking for an Associate Director, Clinical Operations, to independently lead global and complex clinical trials. You will lead the Study Management Team, oversee clinical vendors and CRO(s), and be accountable for ensuring the successful execution and conduct of clinical trial(s). In this role you will directly manage a large, complex early‑phase oncology study, including vendor selection and management, protocol and study document development, feasibility/start‑up, maintenance, and closure. You will lead Clinical Operations, participate on SOP development groups, manage direct reports, and provide stakeholder management for cross‑functional teams. WHAT YOU'LL DO
Provide strategic input and leadership in study set‑up and execution of highly complex oncology clinical trials, supporting multiple trials. Establish and continuously monitor study timelines and budgets, promptly escalating significant risks or changes. Develop and manage study contracts, budgets and timelines. Author/review core study documents including protocol and Informed Consent Forms. Manage CRO, central lab, systems vendors, and ancillary vendors to ensure on‑target deliverables. Develop study plans and relevant study document templates for study teams. Support regulatory strategy and assess trial/program impact and RFIs from multiple countries. Lead RFP process, budget development, and study forecast/planning including timelines. Perform sponsor oversight site visits. Oversight of clinical monitoring activities, including monitoring trip report review and overall site management, ensuring compliance with GCP and applicable regulations, and tracking site performance metrics. Review monitoring trip reports and track resolution of all action items. Manage team with direct reports within therapeutic area. Serve as Clinical Operations lead on cross‑functional project teams and alliance teams. Stakeholder management with internal business partners, key opinion leaders, and external partners on clinical studies. WHO YOU ARE AND WHAT YOU BRING
Bachelor of Science degree (preferably in the life sciences). 10+ years of clinical development experience in the biotech/pharmaceutical industry. Extensive experience working on oncology clinical studies. Experience managing and leading clinical studies from early phase through late stage. Experience leading all stages of clinical trials, including start‑up, maintenance, and close‑out. Thorough understanding of FDA, EMEA, and ROW ICH and GCP guidelines, and cross‑functional clinical processes (data management, biostatistics, medical monitoring, drug safety, regulatory affairs). Experience with regulatory compliance audits and inspections. Experience directing and leading in a complex team environment. Ability to function at a high level when leading a group or managing day‑to‑day details when needed. Flexibility to travel domestically and internationally. WHO WE ARE AND WHAT WE OFFER
The expected salary range for this position is $176,500 to $246,500 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors. Vir Biotechnology’s compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full‑time employees receive a package that includes compensation, bonus and equity, as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non‑accrual paid time off, company shutdown for holidays, commuter benefits, childcare reimbursement, education reimbursement, 401(k) match, and lunch each day in the office. Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time. All employment decisions at Vir Biotechnology are based on legitimate, non‑discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics. This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment. Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees. For hires based in the United States, Vir Biotechnology participates in E‑Verify.
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