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Ionis Pharmaceuticals, Inc.

Computational Biology Post Doctorate Fellow, Biomarker Department

Ionis Pharmaceuticals, Inc., Carlsbad, California, United States, 92002

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Computational Biology Post Doctorate Fellow, Biomarker Department Join Ionis Pharmaceuticals, Inc. as a Postdoctoral Fellow in the Biomarker Department.

Company Overview Headquartered in Carlsbad, CA, Ionis has over three decades of experience pioneering RNA‑targeted medicines and advancing gene‑editing therapies. Our pipeline spans neurology, cardiology, and other areas of high patient need.

Summary We are seeking a highly motivated and outstanding individual to join our Biomarker group as a Postdoctoral Fellow. The role involves supporting the biomarker strategy for Ionis’s wholly owned pipeline, working with external collaborators and cross‑functional teams to analyze proteomic and EEG data, and confirming findings in validation cohorts.

Responsibilities

Design and deploy computational pipelines to process and analyze proteomics and EEG data.

Communicate project status, timelines, and analysis updates to team members.

Integrate findings from omics datasets to support Ionis programs.

Collaborate on additional datasets and contribute to related projects.

Requirements

PhD in computational biology or related field.

Strong background in bioinformatics with experience handling multimodal/omics data.

Experience in data wrangling, QC, normalization, and differential analysis using R, Python, or similar.

Familiarity with packages such as tidyverse, MSstats, DEP2, pandas, numpy, scikit‑learn, GSEA/fgsea, clusterProfiler.

Critical‑thinking, problem‑solving, and strong communication skills.

Ability to manage multiple projects simultaneously and work collaboratively in fast‑paced teams.

Proven ability to be productive in an intense work environment.

Candidate must reside in San Diego or be willing to relocate (full‑time or hybrid).

Travel 0–10 %.

Benefits Ionis offers an excellent benefits package. For details, see https://www.ionis.com/careers/working-at-ionis/#:~:text=our%20employee%20spotlight-,Benefits,-Employees%20are%20rewarded

Salary and Location Salary: $65,000 – $87,000. Location: Carlsbad, CA (full onsite or hybrid).

Contact Instructions NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

EEO Statement Ionis Pharmaceuticals and all its subsidiaries are proud to be EEO employers.

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