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University of Texas Southwestern Medical Center-Quantitative Biomedical Research Center

Postdoctoral Fellow in AI and Data Science

University of Texas Southwestern Medical Center-Quantitative Biomedical Research Center, Dallas, Texas, United States, 75215

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Center Information

The successful candidates will join the research groups led by Dr. Yang Xie and Dr. Guanghua Xiao within the Quantitative Biomedical Research Center (QBRC). QBRC fosters a highly collaborative research environment that brings together computational scientists, clinicians, and biomedical researchers to address pressing challenges in precision medicine and biomedical data science.

QBRC is a renowned research center within the Peter O’Donnell Jr. School of Public Health at the University of Texas Southwestern Medical Center (UTSW). Its mission is to advance quantitative methods and technologies across biomedical research, with a strong emphasis on clinical decision support, translational data science, and innovative computational approaches.

QBRC is also the home of the Data Science and AI for Precision Health Initiative (DAPHI) at UTSW, a major institutional effort that provides access to state‑of‑the‑art computational resources, rich multi‑modal datasets (clinical, imaging, omics, sensors), and a vibrant community of researchers working at the intersection of AI, data science, and precision health.

Available Positions

Dr. Xie and Dr. Xiao’s groups are recruiting a

Postdoctoral Researcher

in one of the three directions, each focusing on distinct but complementary areas of biomedical AI and data science:

Position 1: Postdoctoral Researcher in Medical Image Analysis (Pathology or Radiology)

Develop advanced deep learning methods for radiology or pathology medical imaging

Integrate imaging data with EHR, clinical notes, or genomic data

Conduct research on segmentation, classification, detection, and related imaging tasks

Design self‑supervised or weakly supervised learning approaches for large‑scale datasets

Position 2: Postdoctoral Researcher in EHR‑based Prediction and Clinical Risk Monitoring

Build early warning and clinical deterioration prediction models

Develop continuous clinical risk trajectory modeling frameworks

Model time‑series data such as vitals, labs, and clinical events

Apply deep learning and transformer‑based approaches to longitudinal EHR data

Integrate multi‑modal data (EHR, labs, vitals, imaging, etc.)

Position 3: Postdoctoral Researcher in Spatial Omics and Multi‑Modal Data Integration

Develop computational and machine learning methods for spatial omics data (spatial transcriptomics, spatial proteomics, multiplex imaging)

Model spatial cellular organization, tissue architecture, and microenvironmental interactions

Design multi‑scale models of tissue structure, function, and disease progression

Collaborate with translational and clinical teams within UTSW and DAPHI to advance precision health research using emerging spatial technologies

Environment and Support

Access to state‑of‑the‑art computational infrastructure and secure data platforms

Large‑scale clinical, imaging, EHR, and omics datasets through DAPHI and institutional collaborations

A dynamic, interdisciplinary community of data scientists, statisticians, clinicians, and biomedical researchers

Opportunities for high‑impact publications and cross‑disciplinary collaborations

Position Qualifications (All Positions) Required Qualifications

Ph.D. in Computer Science, Biomedical Engineering, Statistics, Biomedical Sciences, Electrical Engineering, or a related quantitative field

Strong programming skills (e.g., Python, R, or similar)

Demonstrated research experience in machine learning, deep learning, or computational methods

Strong written and oral communication skills

Evidence of research productivity (publications, preprints, or conference papers)

Preferred Qualifications

Experience with medical imaging (for Position 1)

Experience with longitudinal EHR modeling (for Position 2)

Experience with spatial omics or multi‑omics integration (for Position 3)

Prior work with large‑scale clinical, imaging, or omics datasets

Appointment Details

Duration: 2 years

Start Date: As soon as possible

Salary: $65,000–$75,000 per year, commensurate with experience

Benefits: Full UTSW benefits package provided

To Apply Please send your CV to Dr. Guanghua Xiao at: Guanghua.Xiao@UTSouthwestern.edu

Use the subject line:

Postdoctoral Researcher Application – QBRC

Equal Employment Opportunity Statement

UT Southwestern Medical Center is an equal opportunity employer, dedicated to fostering an inclusive and diverse working environment for all members of the university community. We prohibit unlawful discrimination based on race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

To learn more about our commitment to diversity and inclusion, please visit: https://jobs.utsouthwestern.edu/why-work-here/diversity-inclusion/

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