Vertex Pharmaceuticals
Principal Research Associate, Bioanalytical
Vertex Pharmaceuticals, Boston, Massachusetts, us, 02298
Job Description
Principal Research Associate, Bioanalytical
Employer Vertex Pharmaceuticals Incorporated
Location 316-318 Northern Ave, Boston, Massachusetts, 02210
Openings 1
Responsibilities
Conduct bioanalytical assays to support preclinical study sample analysis.
Carry out method development and optimization to quantify target proteins.
Maintain proper documentation of experiments and support QC data review.
Collaborate with cross‑functional teams to review study design and interpret results.
Prepare technical reports and presentations to document and communicate results.
Requirements Employer will accept a Master's degree or equivalent in applied science, biotechnology or a related field and 3 years of experience in the job offered or in a Principal Research Associate, Bioanalytical‑related occupation.
Position requires demonstrable experience in the following:
Perform biochemical and ligand binding assays to support sample analysis from preclinical studies, including protein extraction and quantification, automated capillary western blot, ELISA, MSD and ELISPOT.
Drive splenocyte isolation and cell culture.
Coordinate sample storage, data analysis and interpretation using GraphPad PRISM.
Perform assay development, optimization, and qualification according to FDA guidelines for bioanalytical method validation.
Execute and document assays in an ELN with good laboratory practices and good documentation practices.
Coordinate biodistribution, toxicology and pharmacology studies for investigational new drug application.
Conduct biochemistry and molecular biology on CRISPR strategies for gene and cell therapies.
Perform statistical analysis, including 4PL, regression analysis, standard deviation and coefficients of variation calculations.
Rate of Pay $86,500.00 - $129,800.00
Contact Send Resume to futuretalent@vrtx.com. Reference 12140.705. EOE.
Benefits This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law. Vert... (benefit details truncated for brevity)
Flex Designation On‑Site Designated – work five days per week on‑site with ad hoc flexibility.
Company Information Vertex is a global biotechnology company that invests in scientific innovation.
EEO Statement Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
#J-18808-Ljbffr
Employer Vertex Pharmaceuticals Incorporated
Location 316-318 Northern Ave, Boston, Massachusetts, 02210
Openings 1
Responsibilities
Conduct bioanalytical assays to support preclinical study sample analysis.
Carry out method development and optimization to quantify target proteins.
Maintain proper documentation of experiments and support QC data review.
Collaborate with cross‑functional teams to review study design and interpret results.
Prepare technical reports and presentations to document and communicate results.
Requirements Employer will accept a Master's degree or equivalent in applied science, biotechnology or a related field and 3 years of experience in the job offered or in a Principal Research Associate, Bioanalytical‑related occupation.
Position requires demonstrable experience in the following:
Perform biochemical and ligand binding assays to support sample analysis from preclinical studies, including protein extraction and quantification, automated capillary western blot, ELISA, MSD and ELISPOT.
Drive splenocyte isolation and cell culture.
Coordinate sample storage, data analysis and interpretation using GraphPad PRISM.
Perform assay development, optimization, and qualification according to FDA guidelines for bioanalytical method validation.
Execute and document assays in an ELN with good laboratory practices and good documentation practices.
Coordinate biodistribution, toxicology and pharmacology studies for investigational new drug application.
Conduct biochemistry and molecular biology on CRISPR strategies for gene and cell therapies.
Perform statistical analysis, including 4PL, regression analysis, standard deviation and coefficients of variation calculations.
Rate of Pay $86,500.00 - $129,800.00
Contact Send Resume to futuretalent@vrtx.com. Reference 12140.705. EOE.
Benefits This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law. Vert... (benefit details truncated for brevity)
Flex Designation On‑Site Designated – work five days per week on‑site with ad hoc flexibility.
Company Information Vertex is a global biotechnology company that invests in scientific innovation.
EEO Statement Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
#J-18808-Ljbffr