Johnson & Johnson
Principal Scientist, Biological Research
Johnson & Johnson, San Diego, California, United States, 92189
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Function Discovery & Pre-Clinical/Clinical Development
Job Sub Function Biological Research
Job Category Scientific/Technology
All Job Posting Locations San Diego, California, United States of America
Job Description About Innovative Medicine: Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science‑based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine
We are searching for the best talent for a Principal Scientist, Biological Research to be in La Jolla, CA.
Purpose We are seeking a highly motivated and innovative scientist to lead the development and implementation of advanced immunological cell‑based assays to support drug discovery programs. The successful candidate will be able to lead early drug discovery screening efforts, with a proven ability to apply cutting‑edge technologies in a dynamic and collaborative environment, to advance J&J's Immunology discovery portfolio. This position is within Mechanistic Cellular Pharmacology team.
Responsibilities
Design, develop, and optimize complex cell‑based assays utilizing suitable immune cell types, to support discovery projects from hit identification through lead optimization.
Drive technology innovation for HT disease‑relevant screening platforms in collaboration with automation team.
Lead Immunology discovery programs by leveraging broad technology platforms of DTMP (Discovery Technology and Molecular Pharmacology).
Develop compelling scientific presentations and reports for internal reviews and external publications.
Provide scientific leadership and mentorship to team members; Foster collaborative relationships with stakeholders.
Build and maintain effective scientific networks across internal and external stakeholders.
Ensure compliance with industry standards and best practices in assay development and data integrity.
Qualifications / Requirements Education
Bachelor’s degree is required.
Ph.D. in Pharmacology, Immunology, or related fields is highly preferred.
Required Experience
Minimum 6 years of experience in the pharmaceutical industry and/or academic setting.
Minimum 3 years of pharmaceutical industry experience in assay design and HTS specialization.
Hands‑on flow cytometry and imaging experience.
Strong knowledge of immuno‑cell biology, pharmacology, and in vitro/in vivo pharmacology models.
Excellent problem‑solving skills, open collaborative style, and ability to thrive in a fast‑paced, competitive environment.
Outstanding communication skills to convey scientific credibility and influence decision‑making.
Ability to lead cross‑functional teams and manage multiple priorities effectively.
Positive attitude and strong interpersonal skills for stakeholder engagement.
Preferred
Demonstrated ability to apply big data analytics and computational tools in drug discovery.
Track record of strategic thinking and execution in assay development and technology innovation.
The anticipated base pay range for this position in the US is $117,000 to $201,250.
Compensation and Benefits Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short‑ and long‑term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
Employees are eligible for the following time off benefits:
Vacation - up to 120 hours per calendar year
Sick time - up to 40 hours per calendar year (for employees who reside in the State of Washington - up to 56 hours per calendar year)
Holiday pay, including Floating Holidays – up to 13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
For additional general information on company benefits, please go to https://www.careers.jnj.com/employee-benefits
This job posting is anticipated to close on January 1, 2026. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.
EEO Statement Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.
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Job Function Discovery & Pre-Clinical/Clinical Development
Job Sub Function Biological Research
Job Category Scientific/Technology
All Job Posting Locations San Diego, California, United States of America
Job Description About Innovative Medicine: Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science‑based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine
We are searching for the best talent for a Principal Scientist, Biological Research to be in La Jolla, CA.
Purpose We are seeking a highly motivated and innovative scientist to lead the development and implementation of advanced immunological cell‑based assays to support drug discovery programs. The successful candidate will be able to lead early drug discovery screening efforts, with a proven ability to apply cutting‑edge technologies in a dynamic and collaborative environment, to advance J&J's Immunology discovery portfolio. This position is within Mechanistic Cellular Pharmacology team.
Responsibilities
Design, develop, and optimize complex cell‑based assays utilizing suitable immune cell types, to support discovery projects from hit identification through lead optimization.
Drive technology innovation for HT disease‑relevant screening platforms in collaboration with automation team.
Lead Immunology discovery programs by leveraging broad technology platforms of DTMP (Discovery Technology and Molecular Pharmacology).
Develop compelling scientific presentations and reports for internal reviews and external publications.
Provide scientific leadership and mentorship to team members; Foster collaborative relationships with stakeholders.
Build and maintain effective scientific networks across internal and external stakeholders.
Ensure compliance with industry standards and best practices in assay development and data integrity.
Qualifications / Requirements Education
Bachelor’s degree is required.
Ph.D. in Pharmacology, Immunology, or related fields is highly preferred.
Required Experience
Minimum 6 years of experience in the pharmaceutical industry and/or academic setting.
Minimum 3 years of pharmaceutical industry experience in assay design and HTS specialization.
Hands‑on flow cytometry and imaging experience.
Strong knowledge of immuno‑cell biology, pharmacology, and in vitro/in vivo pharmacology models.
Excellent problem‑solving skills, open collaborative style, and ability to thrive in a fast‑paced, competitive environment.
Outstanding communication skills to convey scientific credibility and influence decision‑making.
Ability to lead cross‑functional teams and manage multiple priorities effectively.
Positive attitude and strong interpersonal skills for stakeholder engagement.
Preferred
Demonstrated ability to apply big data analytics and computational tools in drug discovery.
Track record of strategic thinking and execution in assay development and technology innovation.
The anticipated base pay range for this position in the US is $117,000 to $201,250.
Compensation and Benefits Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short‑ and long‑term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
Employees are eligible for the following time off benefits:
Vacation - up to 120 hours per calendar year
Sick time - up to 40 hours per calendar year (for employees who reside in the State of Washington - up to 56 hours per calendar year)
Holiday pay, including Floating Holidays – up to 13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
For additional general information on company benefits, please go to https://www.careers.jnj.com/employee-benefits
This job posting is anticipated to close on January 1, 2026. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.
EEO Statement Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.
#J-18808-Ljbffr