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Lexeo Therapeutics

Senior Medical Science Liaison (MSL) - Field/HQ Hybrid Role

Lexeo Therapeutics, New York, New York, us, 10261

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Base Pay Range $175,000.00/yr - $215,000.00/yr

Role Summary This Senior Medical Science Liaison (MSL) role offers an opportunity to impact key field-based and HQ Medical Affairs initiatives for Lexeo Therapeutics. As the first MSL, you will shape the scientific landscape for Lexeo’s cardiac gene therapy programs, serving as a strategic, field-based extension of the Medical Affairs team. The role provides exposure to headquarters functions and strategic initiatives, building foundational elements of Lexeo’s field medical organization. You will collaborate with cross‑functional teams, lead Medical Affairs workstreams, and contribute to shaping the Medical Affairs function during Lexeo’s expansion phase. This is a hybrid role; travel is required for field‑facing activities and to the NYHQ office as necessary.

Primary Responsibilities

Leverage scientific expertise to establish and maintain strategically impactful relationships with national, regional, and local Key Opinion Leaders (KOLs) and other healthcare providers (HCPs) for Lexeo’s cardiac gene therapy pipeline, in alignment with medical strategy.

Proactively and reactively engage KOLs and HCPs on disease state education, mechanism of action, emerging and existing clinical data, and the evolution of treatment landscapes for Lexeo’s cardiac gene therapy pipeline.

Support asset‑specific pre‑launch readiness and optimize launch execution through field medical metrics.

Provide internal stakeholders with actionable medical insights gathered from scientific interactions with HCPs.

Explore new areas of scientific and clinical interest to understand unmet needs and how Lexeo’s pipeline programs may address those needs.

Collaborate with Clinical Development and Clinical Operations to support clinical trial sites and investigators as needed.

Stay current on medical and scientific developments in related therapeutic areas through literature review, competitor monitoring, expert networking, and scientific congress attendance.

Complete accurate and timely administrative responsibilities, including reports, projects, and required documentation.

Deliver approved medical and scientific presentations to internal and external stakeholders.

Support evidence generation by facilitating external investigator‑sponsored research (ISR) concept submissions.

Regularly collaborate with field‑based and cross‑functional colleagues to advance clinical practice in a compliant manner.

Support medical and scientific training of cross‑functional teams as needed.

Adhere to Lexeo Therapeutics’ values, culture, and policies.

Required Skills and Qualifications

MD, DO, PhD, PharmD, or a Master’s degree in life sciences with clinical research experience in neuromuscular or cardiac disease; doctorate degrees relevant to the role, RPh, NP, PA, and/or other APPs are also suitable.

3+ years of field experience in the biotech or pharmaceutical industry, or 2+ years of launch experience, or direct patient care experience in cardiology or neurology.

Gene therapy experience preferred, especially in the neuromuscular space.

Ability to interpret key scientific data and translate findings to meet educational and research needs.

Strong interpersonal, presentation, and communication skills, and demonstrated ability to work collaboratively in a dynamic, fast‑paced, team‑oriented environment.

About Lexeo Lexeo Therapeutics is a clinical‑stage genetic medicine company headquartered in New York City, pioneering cardiac genetic medicine candidates to treat the root causes of inherited cardiovascular diseases. Our lead program, LX2006, targets cardiomyopathy associated with Friedreich’s Ataxia and anchors a broader pipeline addressing genetically defined conditions such as hypertrophic and arrhythmogenic cardiomyopathies. Backed by a strong financial foundation, Lexeo is positioned to translate groundbreaking science into durable clinical impact.

Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.

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