CRISPR Therapeutics
Clinical Scientist / Senior Clinical Scientist
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Clinical Scientist / Senior Clinical Scientist
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CRISPR Therapeutics
Company Overview Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research‑stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases. The Nobel Prize‑winning CRISPR science has revolutionized biomedical research and represents a powerful, clinically validated approach with the potential to create a new class of potentially transformative medicines. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic partnerships with leading companies including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly‑owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary Reporting to the Director of Clinical Development, the Clinical Scientist / Senior Clinical Scientist will provide scientific input to early and later stage clinical development programs.
Responsibilities
Contribute to the scientific development of individual clinical studies in alignment with the clinical development plan, including authoring and reviewing clinical documents (e.g., protocols, investigator brochures, CRFs, ICFs, CSRs)
Perform initial review of clinical trial data (safety and efficacy), including assessing for consistency and completeness and providing preliminary assessments and recommendations
Contribute to the oversight in collaboration with the clinical development lead during the conduct of the study
Assist in communicating a clear overview of trial results
Collaborate with internal stakeholders (clinical operations, data management, clinical pharmacology, statistics, safety, commercial, and regulatory affairs) to ensure translation of the clinical protocol into operational deliverables
Collaborate with external stakeholders (CROs, investigators and clinical coordinators) to clarify data submissions
Review and synthesize scientific literature and competitive intelligence to support study and program strategy
Develop scientific and protocol training presentations to support internal and external meetings; e.g., site qualification and initiation, investigator meetings, and training materials
Support preparation of scientific material for conference presentations or publications
Contribute to the authoring and revision of regulatory submissions
Perform analyses and generate scientific slide decks based on clinical, translational and other datasets
Minimum Qualifications
Advanced scientific or clinical degree (e.g., PhD, PharmD, MPH, etc.)
Clinical Scientist: 1–3 years / Senior Clinical Scientist: 4–8+ years of previous experience in clinical or related research
Excellent oral and written communication skills and analytical skills
Ability to work collaboratively in a fast‑paced, team‑based matrix environment
Familiarity with ICH, GCP, and relevant regulatory requirements, and strong analytical and strategic thinking skills, experience with interacting with medical monitors, development operations (preclinical, clinical operations, regulatory affairs, Quality Assurance) and clinical investigators
Preferred Qualifications
Experience in cellular therapies / CAR‑T trials
Experience in Phase 1 / Phase 2 clinical trials
Competencies
Collaborative – Openness, one team, positivity
Undaunted – Fearless, can‑do attitude, self‑starter
Results Orientation – Delivering progress toward our mission; sense of urgency in solving problems; attention to details; practical
Entrepreneurial Spirit – Proactive; ownership mindset; thinks outside the box
Benefits Clinical Scientist: Base pay range of $125,000 to $140,000+ bonus, equity and benefits Senior Clinical Scientist: Base pay range of $150,000 to $170,000+ bonus, equity and benefits
Our employees work at least three days on‑site, creating a collaborative work environment, while maintaining flexible remote work. Certain lab‑based and manufacturing positions are fully on‑site.
Equal Employment Opportunity CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
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Clinical Scientist / Senior Clinical Scientist
role at
CRISPR Therapeutics
Company Overview Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research‑stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases. The Nobel Prize‑winning CRISPR science has revolutionized biomedical research and represents a powerful, clinically validated approach with the potential to create a new class of potentially transformative medicines. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic partnerships with leading companies including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly‑owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary Reporting to the Director of Clinical Development, the Clinical Scientist / Senior Clinical Scientist will provide scientific input to early and later stage clinical development programs.
Responsibilities
Contribute to the scientific development of individual clinical studies in alignment with the clinical development plan, including authoring and reviewing clinical documents (e.g., protocols, investigator brochures, CRFs, ICFs, CSRs)
Perform initial review of clinical trial data (safety and efficacy), including assessing for consistency and completeness and providing preliminary assessments and recommendations
Contribute to the oversight in collaboration with the clinical development lead during the conduct of the study
Assist in communicating a clear overview of trial results
Collaborate with internal stakeholders (clinical operations, data management, clinical pharmacology, statistics, safety, commercial, and regulatory affairs) to ensure translation of the clinical protocol into operational deliverables
Collaborate with external stakeholders (CROs, investigators and clinical coordinators) to clarify data submissions
Review and synthesize scientific literature and competitive intelligence to support study and program strategy
Develop scientific and protocol training presentations to support internal and external meetings; e.g., site qualification and initiation, investigator meetings, and training materials
Support preparation of scientific material for conference presentations or publications
Contribute to the authoring and revision of regulatory submissions
Perform analyses and generate scientific slide decks based on clinical, translational and other datasets
Minimum Qualifications
Advanced scientific or clinical degree (e.g., PhD, PharmD, MPH, etc.)
Clinical Scientist: 1–3 years / Senior Clinical Scientist: 4–8+ years of previous experience in clinical or related research
Excellent oral and written communication skills and analytical skills
Ability to work collaboratively in a fast‑paced, team‑based matrix environment
Familiarity with ICH, GCP, and relevant regulatory requirements, and strong analytical and strategic thinking skills, experience with interacting with medical monitors, development operations (preclinical, clinical operations, regulatory affairs, Quality Assurance) and clinical investigators
Preferred Qualifications
Experience in cellular therapies / CAR‑T trials
Experience in Phase 1 / Phase 2 clinical trials
Competencies
Collaborative – Openness, one team, positivity
Undaunted – Fearless, can‑do attitude, self‑starter
Results Orientation – Delivering progress toward our mission; sense of urgency in solving problems; attention to details; practical
Entrepreneurial Spirit – Proactive; ownership mindset; thinks outside the box
Benefits Clinical Scientist: Base pay range of $125,000 to $140,000+ bonus, equity and benefits Senior Clinical Scientist: Base pay range of $150,000 to $170,000+ bonus, equity and benefits
Our employees work at least three days on‑site, creating a collaborative work environment, while maintaining flexible remote work. Certain lab‑based and manufacturing positions are fully on‑site.
Equal Employment Opportunity CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
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