Barrington James
Regional Business Manager - Rare Genetic Disorders (San Francisco)
Barrington James, San Francisco, California, United States, 94199
Regional Business Manager - Rare Genetic Disorders (San Francisco)
Territory:
Northern California & Nevada
Location:
Field-Based
Overview A global leader in rare and specialty medicine is expanding its commercial team and seeking a
Regional Business Manager
to oversee strategic field operations across Northern California.
This individual will focus on two ultra-rare lysosomal storage disorders -
Gaucher disease
and
Hunter syndrome (MPS II)
- working to improve disease recognition, accelerate diagnostic pathways, and support physicians navigating these complex patient populations.
This territory is scientifically rich, with major academic centers and varied specialty networks. Because new patient identification is limited and highly unpredictable, success hinges on curiosity, persistence, and the ability to build meaningful clinical partnerships.
Core Responsibilities
Develop and execute a regional strategy that expands disease awareness and supports earlier identification of patients across metabolic, genetic, neurology, hematology, and other relevant specialties.
Build long-term relationships with key academic and community institutions, ensuring they have the scientific context and diagnostic tools needed to recognize LSDs earlier.
Use clinical, claims, and market data to map referral pathways, spot emerging opportunities, and determine where educational efforts will have the greatest impact.
Engage in consultative discussions with physicians, supporting them in understanding hallmark symptoms, diagnostic considerations, and patient‑management pathways for these disorders.
Work collaboratively with internal colleagues - medical, access, diagnostics, and patient‑support teams - to ensure seamless resources and education throughout the territory.
Lead educational events, facilitate peer‑to‑peer programs, and represent the organization at scientific meetings and relevant conferences.
Navigate regional reimbursement landscapes, understanding how coverage, specialty pharmacy distribution, and buy‑and‑bill dynamics shape physician and patient experiences.
Maintain a strong field presence while fostering teamwork, accountability, and shared ownership of regional goals.
What You Bring
At least
5+ years
in pharmaceuticals, biotech, medical device, or a closely related field.
A track record of high performance in
specialty, complex, or rare‑disease sales .
Ability to translate scientific and clinical information into meaningful conversations with specialists.
Strong analytical capabilities - able to interpret data, spot patterns, and build plans around them.
Experience working within structured, regulated environments.
Comfort managing reimbursement discussions and navigating payer processes at local and regional levels.
High‑level organizational skills and proficiency with CRM systems and standard analytical tools.
Ability to travel approximately 50% and work occasional evenings or weekends for programs.
Training & Onboarding New hires participate in a structured onboarding program that blends self‑study, clinical deep dives, interactive workshops, and shadowing opportunities. The goal is to ensure every RBM can confidently lead scientific and business‑focused discussions early in their tenure.
Who Will Excel in This Role This position suits someone who:
Enjoys uncovering new opportunities in markets with minimal existing demand
Thinks strategically and adapts quickly to shifting priorities
Can engage confidently with high‑science physicians
Thrives in mission‑driven environments where patient impact is tangible and personal
Is energized by rare diseases, complex diagnostics, and long‑cycle field strategy
Seniority level Mid‑Senior level
Employment type Full‑time
Job function Consulting and Science
Industries Business Consulting and Services and Hospitals and Health Care
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Northern California & Nevada
Location:
Field-Based
Overview A global leader in rare and specialty medicine is expanding its commercial team and seeking a
Regional Business Manager
to oversee strategic field operations across Northern California.
This individual will focus on two ultra-rare lysosomal storage disorders -
Gaucher disease
and
Hunter syndrome (MPS II)
- working to improve disease recognition, accelerate diagnostic pathways, and support physicians navigating these complex patient populations.
This territory is scientifically rich, with major academic centers and varied specialty networks. Because new patient identification is limited and highly unpredictable, success hinges on curiosity, persistence, and the ability to build meaningful clinical partnerships.
Core Responsibilities
Develop and execute a regional strategy that expands disease awareness and supports earlier identification of patients across metabolic, genetic, neurology, hematology, and other relevant specialties.
Build long-term relationships with key academic and community institutions, ensuring they have the scientific context and diagnostic tools needed to recognize LSDs earlier.
Use clinical, claims, and market data to map referral pathways, spot emerging opportunities, and determine where educational efforts will have the greatest impact.
Engage in consultative discussions with physicians, supporting them in understanding hallmark symptoms, diagnostic considerations, and patient‑management pathways for these disorders.
Work collaboratively with internal colleagues - medical, access, diagnostics, and patient‑support teams - to ensure seamless resources and education throughout the territory.
Lead educational events, facilitate peer‑to‑peer programs, and represent the organization at scientific meetings and relevant conferences.
Navigate regional reimbursement landscapes, understanding how coverage, specialty pharmacy distribution, and buy‑and‑bill dynamics shape physician and patient experiences.
Maintain a strong field presence while fostering teamwork, accountability, and shared ownership of regional goals.
What You Bring
At least
5+ years
in pharmaceuticals, biotech, medical device, or a closely related field.
A track record of high performance in
specialty, complex, or rare‑disease sales .
Ability to translate scientific and clinical information into meaningful conversations with specialists.
Strong analytical capabilities - able to interpret data, spot patterns, and build plans around them.
Experience working within structured, regulated environments.
Comfort managing reimbursement discussions and navigating payer processes at local and regional levels.
High‑level organizational skills and proficiency with CRM systems and standard analytical tools.
Ability to travel approximately 50% and work occasional evenings or weekends for programs.
Training & Onboarding New hires participate in a structured onboarding program that blends self‑study, clinical deep dives, interactive workshops, and shadowing opportunities. The goal is to ensure every RBM can confidently lead scientific and business‑focused discussions early in their tenure.
Who Will Excel in This Role This position suits someone who:
Enjoys uncovering new opportunities in markets with minimal existing demand
Thinks strategically and adapts quickly to shifting priorities
Can engage confidently with high‑science physicians
Thrives in mission‑driven environments where patient impact is tangible and personal
Is energized by rare diseases, complex diagnostics, and long‑cycle field strategy
Seniority level Mid‑Senior level
Employment type Full‑time
Job function Consulting and Science
Industries Business Consulting and Services and Hospitals and Health Care
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