Stoke Therapeutics
Director/Senior Director, Medical Affairs - South
Stoke Therapeutics, Bedford, Massachusetts, us, 01730
Regional Medical Director – South
Stoke Therapeutics
(Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. We develop antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Our first medicine in development, zorevunersen, has demonstrated disease modification in Dravet syndrome and is in Phase 3. We partnered with Biogen in 2025 for commercialization. We also develop STK-002 for ADOA and early research in Syngap1.
Position Purpose The Director/Senior Director, Medical Affairs – RMD (South) will be a core member of the global medical affairs team and help establish core medical capabilities at Stoke. This field-based role primarily represents Stoke with a network of external clinical experts or KOLs in a regional area, advancing prioritized Medical Affairs activities in collaboration with cross‑functional teams.
Key Responsibilities
Work closely with clinical operations and development teams to support Stoke clinical study efforts, including site identification and engagement to advance enrollment while fostering collaborative research relationships.
Establish and maintain highly credible scientific relationships with academic and medical thought leaders.
Serve as field medical point of scientific/clinical contact or support for national and regional payers, healthcare systems, integrated delivery networks and managed care organizations.
Work closely with internal team members to facilitate and support congress strategy at scientific meetings, including KOL engagement planning, insight gathering on key topics, and interpretative reports to share with cross‑functional teams.
Develop, share, and discuss ongoing clinical insights with cross‑functional members to ensure awareness and understanding of KOL perspectives to inform and guide strategic decision‑making.
Develop strategic profiles for top experts and clinical staff at centers of comprehensive care, to help identify key opportunities for ongoing education and collaboration.
Develop key performance and reputation measures to ensure ongoing alignment of Stoke activities to KOL and HCP expectations and needs.
Collaborate closely with other functions including clinical, commercial and PR/IR/Advocacy to engage and support external stakeholder needs through activities such as scientific education, advisory boards, investigator meetings, publications, congresses, and other activities of interest.
Perform typical office duties when not traveling.
All other duties as assigned.
Required Skills & Experience
Advanced scientific or clinical degree, with at least 10+ years in relevant clinical/scientific fields and 5+ years of Medical Affairs experience, with significant focus on field medical activities.
Experience with pre‑launch and rare diseases in epilepsy/neurology highly preferred.
Prior track record of success and proficiency working directly with clinical and academic experts.
Knowledge of and engagement experience with national and regional payers is a plus.
Excellent verbal and written communication skills and exceptional interpersonal skills.
Demonstrated skills in leading and mentoring others.
Good judgment, adaptability, and ability to thrive in a shifting environment.
A strategic, passionate, self‑starter who takes initiative.
Ability to work independently and function effectively as a team member.
Excellent problem‑solving skills.
Valid driver’s license and ability to travel as necessary.
Location Bedford, MA (remote, field‑based in the continental United States; regionally designated area).
Travel Approximately 60%+ travel, including overnight, international, and occasional weekend travel.
Compensation & Benefits At Stoke Therapeutics we offer a comprehensive, competitive total rewards program. For Director level the anticipated salary range is $236,000–$266,000; for Senior Director level it is $294,000–$329,000. The final offer will be determined by scope, experience, educational background, market benchmarks, internal equity, and geography. In addition to base salary, there is annual bonus and equity participation. Benefits include medical, dental, vision, life, long‑term and short‑term disability insurance; paid parental leave; 401(k) plan with company match; unlimited vacation; tuition assistance; and participation in our Employee Stock Purchase Program (ESPP).
Interested Candidates Visit https://www.stoketherapeutics.com/careers/ to apply directly to the position listed in our Career Center.
EEO Statement All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E‑Verify.
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(Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. We develop antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Our first medicine in development, zorevunersen, has demonstrated disease modification in Dravet syndrome and is in Phase 3. We partnered with Biogen in 2025 for commercialization. We also develop STK-002 for ADOA and early research in Syngap1.
Position Purpose The Director/Senior Director, Medical Affairs – RMD (South) will be a core member of the global medical affairs team and help establish core medical capabilities at Stoke. This field-based role primarily represents Stoke with a network of external clinical experts or KOLs in a regional area, advancing prioritized Medical Affairs activities in collaboration with cross‑functional teams.
Key Responsibilities
Work closely with clinical operations and development teams to support Stoke clinical study efforts, including site identification and engagement to advance enrollment while fostering collaborative research relationships.
Establish and maintain highly credible scientific relationships with academic and medical thought leaders.
Serve as field medical point of scientific/clinical contact or support for national and regional payers, healthcare systems, integrated delivery networks and managed care organizations.
Work closely with internal team members to facilitate and support congress strategy at scientific meetings, including KOL engagement planning, insight gathering on key topics, and interpretative reports to share with cross‑functional teams.
Develop, share, and discuss ongoing clinical insights with cross‑functional members to ensure awareness and understanding of KOL perspectives to inform and guide strategic decision‑making.
Develop strategic profiles for top experts and clinical staff at centers of comprehensive care, to help identify key opportunities for ongoing education and collaboration.
Develop key performance and reputation measures to ensure ongoing alignment of Stoke activities to KOL and HCP expectations and needs.
Collaborate closely with other functions including clinical, commercial and PR/IR/Advocacy to engage and support external stakeholder needs through activities such as scientific education, advisory boards, investigator meetings, publications, congresses, and other activities of interest.
Perform typical office duties when not traveling.
All other duties as assigned.
Required Skills & Experience
Advanced scientific or clinical degree, with at least 10+ years in relevant clinical/scientific fields and 5+ years of Medical Affairs experience, with significant focus on field medical activities.
Experience with pre‑launch and rare diseases in epilepsy/neurology highly preferred.
Prior track record of success and proficiency working directly with clinical and academic experts.
Knowledge of and engagement experience with national and regional payers is a plus.
Excellent verbal and written communication skills and exceptional interpersonal skills.
Demonstrated skills in leading and mentoring others.
Good judgment, adaptability, and ability to thrive in a shifting environment.
A strategic, passionate, self‑starter who takes initiative.
Ability to work independently and function effectively as a team member.
Excellent problem‑solving skills.
Valid driver’s license and ability to travel as necessary.
Location Bedford, MA (remote, field‑based in the continental United States; regionally designated area).
Travel Approximately 60%+ travel, including overnight, international, and occasional weekend travel.
Compensation & Benefits At Stoke Therapeutics we offer a comprehensive, competitive total rewards program. For Director level the anticipated salary range is $236,000–$266,000; for Senior Director level it is $294,000–$329,000. The final offer will be determined by scope, experience, educational background, market benchmarks, internal equity, and geography. In addition to base salary, there is annual bonus and equity participation. Benefits include medical, dental, vision, life, long‑term and short‑term disability insurance; paid parental leave; 401(k) plan with company match; unlimited vacation; tuition assistance; and participation in our Employee Stock Purchase Program (ESPP).
Interested Candidates Visit https://www.stoketherapeutics.com/careers/ to apply directly to the position listed in our Career Center.
EEO Statement All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E‑Verify.
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