Revolution Medicines
Vice President, Clinical Business Operations and Strategy
Revolution Medicines, San Francisco, California, United States, 94199
Vice President, Clinical Business Operations and Strategy
Join to apply for the
Vice President, Clinical Business Operations and Strategy
role at
Revolution Medicines .
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies.
The Opportunity The Vice President, Clinical Business Strategy and Operations serves as a critical strategic partner to the SVP of Clinical Operations and the Development Leadership Team, driving alignment, execution, and operational excellence related to the business operations of our global clinical programs. This role integrates visionary leadership, high-level strategic planning, organizational enablement, fiscal strategy and governance oversight with leadership of the company’s global clinical business operations activities—ensuring that partnerships, vendors, and financial commitments align with scientific and corporate priorities.
The ideal candidate is a seasoned biotech executive who thrives at the intersection of science, strategy, and business operations, with demonstrated expertise in clinical outsourcing, vendor management, cross‑functional execution, strategic planning, clinical finance, project management, business planning & operations, leadership and mentoring, and fostering cross organisational collaboration within high‑growth scaling biotechnology organisations.
Responsibilities
Create long‑term strategic direction for Revolution Medicines’ clinical business operations, ensuring that outsourcing models, vendor partnerships, and financial strategies support the company’s integrated R&D and commercialization goals.
Serve as trusted advisor and thought partner to leadership to translate the evolving strategic vision of clinical operations and policies into operational execution.
Create functional alignment with Finance, Legal and Development functions for financial and resource deployment with strategic priorities.
Lead transformation of outsourcing and business partnership models to drive efficiency of our clinical trial execution in alignment with corporate objectives and growth trajectory.
Lead the global vendor outsourcing function, responsible for developing, negotiating, and managing agreements with CROs, investigators, clinical sites, and strategic partners.
Establish standardized contracting frameworks, performance metrics, and SLAs to enhance consistency, speed, and compliance across programmes.
Design and operationalise a scalable operating model to deliver required CTA volumes based on RevMed needs.
Identify gaps, aligning building of solutions and drive evaluation, selection, deployment and oversight of clinical outsourcing agreements processes.
Develop and maintain a vendor governance model that ensures transparency, quality and fiscal responsibility across global partnerships.
Establish metrics and governance to ensure performance, compliance and fiscal responsibility.
Implement metrics and dashboards to monitor contracting cycle times, vendor performance and clinical business operations efficiency.
Establish functional effectiveness by cultivating leadership capability across the CORE team and embedding a values‑driven culture of collaboration, innovation, accountability, growth and strategic foresight.
Partner with Development Program Management, Business Operations and other functional leaders to develop and implement cross‑functional processes that maximise organisational impact, scalability and compliance with ICH/GCP and global standards.
Set roadmap for strategic change management across clinical operations, leveraging best practices to ensure successful and sustainable adoption.
Required Skills, Experience and Education
20+ years of progressive leadership experience in biotechnology or pharmaceuticals, including at least 8 years in clinical outsourcing, contracting or business operations.
Minimum of 10 years clinical operations systems project and line management experience.
Master’s degree in business, finance or life sciences required; MBA preferred.
Extensive experience managing business operations related to global phase 1–3 clinical trials budgets.
Demonstrable record of strong leadership and teamwork.
Strong understanding of clinical contracting, budgeting and development processes, outsourcing models and global regulatory frameworks.
Demonstrated excellence in vendor negotiation, contracting and governance across CRO, lab and site partnerships.
Working knowledge of interplay among functions related to clinical trial conduct.
Exceptional organisational, analytical and interpersonal skills with ability to influence and drive results across functions.
Strong knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials.
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high‑energy environment.
Excellent written and verbal communication skills.
Ability to act as an ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.
Demonstrated ability to multi‑task, prioritise options, anticipate challenges and execute goals as a member of an interdisciplinary team.
Key Competencies
Strategic and Systems Thinking.
Financial and Contractual Acumen.
Executive Presence and Communication.
Operational Rigor and Process Excellence.
Change Leadership and Organisational Design.
Collaborative and Servant Leadership Style.
Preferred Skills
Experience working with cooperative group studies and investigator‑sponsored trials.
Experience operating in fast‑paced, early to mid‑stage biotech environments.
Base Pay Salary Range $284,000 — $355,000 USD
Equal Opportunity Employer Revolution Medicines is an equal‑opportunity employer and prohibits unlawful discrimination based on race, colour, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition and veteran status.
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Vice President, Clinical Business Operations and Strategy
role at
Revolution Medicines .
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies.
The Opportunity The Vice President, Clinical Business Strategy and Operations serves as a critical strategic partner to the SVP of Clinical Operations and the Development Leadership Team, driving alignment, execution, and operational excellence related to the business operations of our global clinical programs. This role integrates visionary leadership, high-level strategic planning, organizational enablement, fiscal strategy and governance oversight with leadership of the company’s global clinical business operations activities—ensuring that partnerships, vendors, and financial commitments align with scientific and corporate priorities.
The ideal candidate is a seasoned biotech executive who thrives at the intersection of science, strategy, and business operations, with demonstrated expertise in clinical outsourcing, vendor management, cross‑functional execution, strategic planning, clinical finance, project management, business planning & operations, leadership and mentoring, and fostering cross organisational collaboration within high‑growth scaling biotechnology organisations.
Responsibilities
Create long‑term strategic direction for Revolution Medicines’ clinical business operations, ensuring that outsourcing models, vendor partnerships, and financial strategies support the company’s integrated R&D and commercialization goals.
Serve as trusted advisor and thought partner to leadership to translate the evolving strategic vision of clinical operations and policies into operational execution.
Create functional alignment with Finance, Legal and Development functions for financial and resource deployment with strategic priorities.
Lead transformation of outsourcing and business partnership models to drive efficiency of our clinical trial execution in alignment with corporate objectives and growth trajectory.
Lead the global vendor outsourcing function, responsible for developing, negotiating, and managing agreements with CROs, investigators, clinical sites, and strategic partners.
Establish standardized contracting frameworks, performance metrics, and SLAs to enhance consistency, speed, and compliance across programmes.
Design and operationalise a scalable operating model to deliver required CTA volumes based on RevMed needs.
Identify gaps, aligning building of solutions and drive evaluation, selection, deployment and oversight of clinical outsourcing agreements processes.
Develop and maintain a vendor governance model that ensures transparency, quality and fiscal responsibility across global partnerships.
Establish metrics and governance to ensure performance, compliance and fiscal responsibility.
Implement metrics and dashboards to monitor contracting cycle times, vendor performance and clinical business operations efficiency.
Establish functional effectiveness by cultivating leadership capability across the CORE team and embedding a values‑driven culture of collaboration, innovation, accountability, growth and strategic foresight.
Partner with Development Program Management, Business Operations and other functional leaders to develop and implement cross‑functional processes that maximise organisational impact, scalability and compliance with ICH/GCP and global standards.
Set roadmap for strategic change management across clinical operations, leveraging best practices to ensure successful and sustainable adoption.
Required Skills, Experience and Education
20+ years of progressive leadership experience in biotechnology or pharmaceuticals, including at least 8 years in clinical outsourcing, contracting or business operations.
Minimum of 10 years clinical operations systems project and line management experience.
Master’s degree in business, finance or life sciences required; MBA preferred.
Extensive experience managing business operations related to global phase 1–3 clinical trials budgets.
Demonstrable record of strong leadership and teamwork.
Strong understanding of clinical contracting, budgeting and development processes, outsourcing models and global regulatory frameworks.
Demonstrated excellence in vendor negotiation, contracting and governance across CRO, lab and site partnerships.
Working knowledge of interplay among functions related to clinical trial conduct.
Exceptional organisational, analytical and interpersonal skills with ability to influence and drive results across functions.
Strong knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials.
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high‑energy environment.
Excellent written and verbal communication skills.
Ability to act as an ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.
Demonstrated ability to multi‑task, prioritise options, anticipate challenges and execute goals as a member of an interdisciplinary team.
Key Competencies
Strategic and Systems Thinking.
Financial and Contractual Acumen.
Executive Presence and Communication.
Operational Rigor and Process Excellence.
Change Leadership and Organisational Design.
Collaborative and Servant Leadership Style.
Preferred Skills
Experience working with cooperative group studies and investigator‑sponsored trials.
Experience operating in fast‑paced, early to mid‑stage biotech environments.
Base Pay Salary Range $284,000 — $355,000 USD
Equal Opportunity Employer Revolution Medicines is an equal‑opportunity employer and prohibits unlawful discrimination based on race, colour, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition and veteran status.
#J-18808-Ljbffr