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Madrigal Pharmaceuticals

Executive Director, Global Publications

Madrigal Pharmaceuticals, Conshohocken, Pennsylvania, United States

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Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Role Summary The Executive Director, Global Publications provides enterprise-wide strategic leadership for the development, governance, and execution of the global scientific publications program within Medical Affairs at Madrigal Pharmaceuticals. This role defines the long-term publications strategy and ensures alignment with corporate medical strategy, asset lifecycle planning, and global scientific communications objectives, while maintaining full regulatory, legal, and industry compliance.

As a key member of the Scientific Communications Leadership Team, the Executive Director sets the vision, standards, and operating model for global publications, partnering closely with cross-functional stakeholders to ensure timely, data-driven publication plans, and oversees end-to-end lifecycle management from strategic planning through post-publication optimization. The role leads a high-performing global team and vendor ecosystem to deliver high-impact scientific communications that strengthen Madrigal’s scientific leadership with both internal and external stakeholders.

The position reports to the Vice President of Scientific Communication (or assigned delegate) and is a hybrid role (three days per week at Conshohocken, PA).

All incumbents are responsible for following applicable Division & Madrigal policies and procedures.

Key Responsibilities and Primary Activities

Publications Strategy and Governance

Define and own the global publications strategy, prioritizing scientific communication needs for all internal and external stakeholders across the product’s lifecycle

Ensure annual and long-range publication plans are fully aligned with Medical Affairs strategy, asset lifecycle planning, clinical development milestones, and corporate scientific communication objectives

Establish and oversee the global publications operating model, including governance frameworks, decision rights, execution standards, and budget oversight

Monitor and interpret evolving scientific, disease-state, and industry publication trends, translating insights into forward-looking publication strategy

Drive innovation in planning, including publication extenders, voice of the patient and appropriate use of AI technology

Publication Standards

Provide strategic oversight for the development of abstracts, posters, oral presentations, and peer-reviewed manuscripts to ensure scientific rigors, consistency, and enterprise alignment

Ensure all publications adhere to GPP, ICMJE, AMA, regulatory, legal, and industry compliance standards, with global consistency

Oversee end-to-end content quality assurance, including planning analyses, data verification, scientific accuracy, and alignment to core scientific narratives

Ensure standards for publication repositories, archival systems, and version control across regions and vendors

Executive Collaboration & External Engagement

Serve as the senior leader to external authors, investigators, scientific societies, and congress leadership to shape Madrigal’s scientific presence. This includes leadership of any external publication steering committees.

Act as the strategic publications partner to Medical Affairs, Clinical Development, Regulatory, Commercial, Market Access, Legal, Compliance, and other relevant divisions to ensure alignment and impact of publications

Ensure the Publication Steering Review Team, is driving integrated prioritization and cross-functional alignment across Med Affairs and Clinical Development

Provide executive oversight of external publication vendors and agencies, including selection, contracting, RFPs, performance management, and budget governance, with focus on publications

Global Program Leadership

Direct the global publications portfolio, ensuring timely, high-quality, and high-impact execution across all regions

Integrate publications strategy with disease-state communications, congress planning, medical education, lexicons, and global scientific narratives

Oversee global budget planning and optimization for all publications activities, vendor engagements, and associated initiatives

Organizational Leadership & Talent Development

Build, lead, and scale a high-performing global publications team

Establish a culture of scientific excellence, accountability, and continuous improvement through coaching, succession planning, and performance management

Align team capabilities and resourcing models with current and future needs, ensuring readiness to support any additional assets or program expansions

Compliance & Quality

Ensure all activities comply with company SOPs, industry standards, and applicable regulations

Uphold the highest ethical standards in all internal and external engagements

Travel Requirement

Willingness to travel up to 30% for conferences, various corporate locations, and stakeholder meetings, including overnight trips

Required Qualifications, Skills & Experience

Advanced terminal degree in a scientific or healthcare discipline (MD, PharmD, PhD, DNP, MPH, MS or equivalent) with CMPP certification desired

A minimum of 18+ years of progressive experience in healthcare, clinical research, medical affairs, or scientific communications, including significant executive-level leadership responsibility

Extensive headquarters and global publications leadership experience, with direct accountability for enterprise publications strategy and governance

Demonstrated success partnering at the senior and executive leadership level with Clinical Development, HEOR/RWE, Biostatistics, Regulatory, Commercial, and Medical Affairs

Expertise in medical writing, global publications planning, and scientific communications, with a track record of high-impact peer-reviewed output

Proven experience leading large, complex portfolios, balancing multiple global priorities, timelines, and cross-functional interdependencies

Executive presence and exceptional communication skills, with the ability to influence at the C-suite, Board, and external scientific leadership levels

Deep working knowledge of ICMJE, AMA, FDA, EU, and global compliance standards with demonstrated audit-ready governance experience

Recognized ability to build and sustain senior-level relationships with key opinion leaders, editors of journals, congress leadership and others

Demonstrated ability to translate complex clinical and scientific data into enterprise scientific narratives and strategy.

Proven enterprise-level insight into scientific content and communications trends, including digital, data, and innovation-driven publishing models

Experience interfacing with business and corporate leadership to shape corporate medical and scientific strategy

Strong knowledge of US/EU healthcare systems, global regulatory standards (e.g., FDA, CE), and medical affairs compliance standards

Proficiency in Microsoft Office Suite, virtual communication platforms (e.g., Zoom, Teams), and CRM systems (e.g., Veeva)

Preferred Attributes

Clinical experience in a healthcare environment (e.g., medicine, pharmacy, laboratory, nursing)

In-depth knowledge of liver disease; experience in cardiometabolic health, or Metabolic Dysfunction–Associated Steatohepatitis (MASH)

Adaptable and proactive in a fast-paced, evolving environment

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. The base salary range for this position is $293,000- $358,000 per year

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.

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