Olema Oncology
Director of Facilities, Laboratory Operations and EHS
Olema Oncology, San Francisco, California, United States, 94199
Director of Facilities, Laboratory Operations and EHS
Olema Oncology is dedicated to developing better medicines for breast cancer and beyond. Our lead program, palazestrant (OP-1250), is a complete estrogen receptor antagonist (CERAN) currently in development for metastatic breast cancer with blockbuster potential as a monotherapy and in combination in ER+/HER2- metastatic breast cancer. Our follow‑on product candidate, OP-3136, is a potent KAT6 inhibitor with best‑in‑class potential.
As the Director of Facilities, Laboratory Operations and EHS reporting to the VP of IT, Real Estate and Facilities Lab Operations you will be responsible for the strategic leadership, operational excellence, and long‑term planning of Olema’s facilities and laboratory environments across multiple sites. In this role you will own the full lifecycle of facilities and lab operations, from day‑to‑day execution to large‑scale initiatives including laboratory buildouts, office and lab relocations. This role will oversee three Olema locations, including BSL2 laboratory environments and corporate office space, and serves as a senior partner to Research, IT, Real Estate, Finance, and Executive Leadership.
This role is based in our San Francisco office and will require 15% travel.
Facilities, Real Estate & Capital Execution
Lead and execute all facilities operations and physical infrastructure activities across Olema’s locations
Own the execution of Real Estate strategy, including site readiness, lease transitions, expansions, consolidations, and exits
Lead office and laboratory moves and building relocations, with full accountability for planning, execution, risk management, and stabilization
Direct laboratory and office buildouts end‑to‑end, from programming and design through permitting, construction, commissioning, and occupancy
Execute capital projects in active lab environments while maintaining safety, compliance, and continuity of scientific operations
Develop and enforce facilities standards, policies, procedures, and SOPs
Own physical security programs, including access control, badging, alarms, vendor oversight, and incident response
Control facilities operating and capital budgets, including forecasting, spend management, and cost accountability
Lead emergency planning and response across all facilities
Direct shipping and receiving operations, including Hazardous Materials and Dangerous Goods compliance
Own all workplace services across all locations, including office supplies, beverage and food programs, janitorial services, and waste management, with accountability for vendor performance, cost control, and service quality
Laboratory Operations
Support the research team with all infrastructure needs, including vendor relationships and management, service and maintenance of scientific equipment, hazardous waste management, and cell culture support
Monitor critical systems and provide 24‑hour on‑call support in case of system failure
Develop and maintain awareness of health and safety issues within the company, ensure compliance with company policies through appropriate training of employees, and manage safety consultants effectively
Manage and maintain cryo storage, liquid nitrogen, compressed gas system, emergency generator system, vacuum and compressed air systems
Manage critical laboratory systems, including but not limited to HVAC, monitoring, systems and equipment maintenance, to ensure uninterrupted functionality and optimal performance
Oversee all aspects of shipping and receiving operations, including inventory management, packaging, and transportation logistics, to facilitate efficient and timely movement of goods
Lead and execute laboratory operations to ensure uninterrupted, compliant research support
Environmental Health & Safety (EHS) Ownership
Accountable owner of Olema’s Environmental Health and Safety program
Design, implement, enforce, and continuously improve EHS policies, procedures, training, and compliance programs
Lead all regulatory inspections, audits, and agency interactions
Own hazardous waste permitting, reporting, corrective actions, and compliance documentation
Embed EHS requirements into lab design, construction, moves, and daily operations
Direct EHS consultants and contractors with clear accountability for outcomes
Maintain, train and scale EHS programs supporting BSL‑2 laboratory environments
Ideal Candidate Profile Knowledge
Bachelor’s Degree required
Strategic Facilities Manager (SFM) and Certified Safety Professional (CSP) certifications required
Proven track record of successful facilities leadership experience
Expert‑level knowledge of facilities, laboratory operations, and EHS in biotech or life sciences
Strong project management, planning, organization, and time management skills
Experience
Minimum of 10+ years of experience with a minimum of 5 years of facilities management experience, including oversight of lab environments
Created and ran an EHS program for a BSL2 Lab a must have
Demonstrated ownership of lab buildouts relocations, and real estate execution
Hands‑on facilities, lab operations, and leadership experience who can move seamlessly between strategic planning and tactical execution, particularly in challenging laboratory settings that require sound judgment, calm decision‑making, and rigorous operational discipline
Demonstrated experience working in a demanding and fast‑paced lab environment where uptime, safety, compliance, and responsiveness are critical, and where competing priorities and situational ambiguity are the norm rather than the exception
Attributes
Highly organized with strong attention to detail, clarity, and accuracy
Solutions‑oriented with a meticulous eye for detail and thrives in a fast‑paced, problem‑solving environment
Proactive, self‑motivated, and results‑oriented with a “bias for action”
Collaborative team player who thrives in a cross‑functional environment
Flexible and adaptable to evolving business needs and technology trends
Excellent written, verbal and interpersonal communication skills and ability to adapt communication styles to varied internal and external partners
The base pay range for this position is expected to be
$210,000 - $220,000
annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.
Important Information We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long‑term careers. A Summary of Benefits is available for all applicants.
Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes.
Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in
@olema.com . Our official corporate website is
olema.com ; our careers page is
olema.com/careers ; our LinkedIn page is
linkedin.com/company/olema-oncology . Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in‑person interview.
Seniority level
Director
Employment type
Full‑time
Job function
General Business
Industries: Biotechnology Research and Pharmaceutical Manufacturing
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As the Director of Facilities, Laboratory Operations and EHS reporting to the VP of IT, Real Estate and Facilities Lab Operations you will be responsible for the strategic leadership, operational excellence, and long‑term planning of Olema’s facilities and laboratory environments across multiple sites. In this role you will own the full lifecycle of facilities and lab operations, from day‑to‑day execution to large‑scale initiatives including laboratory buildouts, office and lab relocations. This role will oversee three Olema locations, including BSL2 laboratory environments and corporate office space, and serves as a senior partner to Research, IT, Real Estate, Finance, and Executive Leadership.
This role is based in our San Francisco office and will require 15% travel.
Facilities, Real Estate & Capital Execution
Lead and execute all facilities operations and physical infrastructure activities across Olema’s locations
Own the execution of Real Estate strategy, including site readiness, lease transitions, expansions, consolidations, and exits
Lead office and laboratory moves and building relocations, with full accountability for planning, execution, risk management, and stabilization
Direct laboratory and office buildouts end‑to‑end, from programming and design through permitting, construction, commissioning, and occupancy
Execute capital projects in active lab environments while maintaining safety, compliance, and continuity of scientific operations
Develop and enforce facilities standards, policies, procedures, and SOPs
Own physical security programs, including access control, badging, alarms, vendor oversight, and incident response
Control facilities operating and capital budgets, including forecasting, spend management, and cost accountability
Lead emergency planning and response across all facilities
Direct shipping and receiving operations, including Hazardous Materials and Dangerous Goods compliance
Own all workplace services across all locations, including office supplies, beverage and food programs, janitorial services, and waste management, with accountability for vendor performance, cost control, and service quality
Laboratory Operations
Support the research team with all infrastructure needs, including vendor relationships and management, service and maintenance of scientific equipment, hazardous waste management, and cell culture support
Monitor critical systems and provide 24‑hour on‑call support in case of system failure
Develop and maintain awareness of health and safety issues within the company, ensure compliance with company policies through appropriate training of employees, and manage safety consultants effectively
Manage and maintain cryo storage, liquid nitrogen, compressed gas system, emergency generator system, vacuum and compressed air systems
Manage critical laboratory systems, including but not limited to HVAC, monitoring, systems and equipment maintenance, to ensure uninterrupted functionality and optimal performance
Oversee all aspects of shipping and receiving operations, including inventory management, packaging, and transportation logistics, to facilitate efficient and timely movement of goods
Lead and execute laboratory operations to ensure uninterrupted, compliant research support
Environmental Health & Safety (EHS) Ownership
Accountable owner of Olema’s Environmental Health and Safety program
Design, implement, enforce, and continuously improve EHS policies, procedures, training, and compliance programs
Lead all regulatory inspections, audits, and agency interactions
Own hazardous waste permitting, reporting, corrective actions, and compliance documentation
Embed EHS requirements into lab design, construction, moves, and daily operations
Direct EHS consultants and contractors with clear accountability for outcomes
Maintain, train and scale EHS programs supporting BSL‑2 laboratory environments
Ideal Candidate Profile Knowledge
Bachelor’s Degree required
Strategic Facilities Manager (SFM) and Certified Safety Professional (CSP) certifications required
Proven track record of successful facilities leadership experience
Expert‑level knowledge of facilities, laboratory operations, and EHS in biotech or life sciences
Strong project management, planning, organization, and time management skills
Experience
Minimum of 10+ years of experience with a minimum of 5 years of facilities management experience, including oversight of lab environments
Created and ran an EHS program for a BSL2 Lab a must have
Demonstrated ownership of lab buildouts relocations, and real estate execution
Hands‑on facilities, lab operations, and leadership experience who can move seamlessly between strategic planning and tactical execution, particularly in challenging laboratory settings that require sound judgment, calm decision‑making, and rigorous operational discipline
Demonstrated experience working in a demanding and fast‑paced lab environment where uptime, safety, compliance, and responsiveness are critical, and where competing priorities and situational ambiguity are the norm rather than the exception
Attributes
Highly organized with strong attention to detail, clarity, and accuracy
Solutions‑oriented with a meticulous eye for detail and thrives in a fast‑paced, problem‑solving environment
Proactive, self‑motivated, and results‑oriented with a “bias for action”
Collaborative team player who thrives in a cross‑functional environment
Flexible and adaptable to evolving business needs and technology trends
Excellent written, verbal and interpersonal communication skills and ability to adapt communication styles to varied internal and external partners
The base pay range for this position is expected to be
$210,000 - $220,000
annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.
Important Information We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long‑term careers. A Summary of Benefits is available for all applicants.
Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes.
Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in
@olema.com . Our official corporate website is
olema.com ; our careers page is
olema.com/careers ; our LinkedIn page is
linkedin.com/company/olema-oncology . Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in‑person interview.
Seniority level
Director
Employment type
Full‑time
Job function
General Business
Industries: Biotechnology Research and Pharmaceutical Manufacturing
#J-18808-Ljbffr