Undisclosed Biotech Startup
Scientist – Peptide & Oligonucleotide Chemist
Undisclosed Biotech Startup, San Francisco, California, United States, 94199
Base Pay Range
$100,000.00/yr - $140,000.00/yr
About Us
We’re a stealth-mode, venture-backed biotech startup based in the Bay Area, developing breakthrough technology at the intersection of genetics and reproductive health. We’re backed by world‑class investors, have raised our first institutional round, and are now expanding our team. We operate our primary lab in the Peninsula and we’re in the process of getting access to additional access to world‑class chemistry facilities in the East Bay. Applicants must be willing to commute between campuses.
About the Role
We’re seeking a scientist with deep expertise in nucleic acid analog synthesis and assay development to join our R&D team. In this role, you’ll collaborate closely with our founding team to develop and optimize our cellular assays. You will design and optimize the synthesis of nucleic acid analogs, characterize the synthetic output, and assist in the evaluation of reagent efficacy. This is a hands‑on, high‑impact role at the earliest stage of the company; perfect for someone excited to shape the future of fertility and reproductive health. PhD (or equivalent experience) in organic chemistry, biomolecular chemistry, chemical biology, nucleic acid chemistry, or closely related field required.
Required Skills
Extensive, hands‑on experience with synthetic nucleic acid or peptide chemistry Experience with PNA OR a closely related polymer synthesis workflows and troubleshooting Knowledge of nucleotide or nucleic acid binding principles: hybridization thermodynamics, mismatch discrimination, duplex stability, etc. Proficiency in peptide and nucleic acid purification and characterization via HPLC, LC‑MS, etc Ability to design and interpret in‑vitro / in‑silico binding or stability assays Excellent communication and organizational skills Excited to work in a dynamic, early‑stage startup atmosphere Motivated, independent, and excited to help build new technology Comfort working across multiple lab sites/campuses
Preferred Skills
Experience with in vivo or cellular assays involving nucleic acid probes Knowledge of alternative nucleic acid backbone chemistries (e.g., morpholino, modified RNAs) Prior startup or technology development experience
Pay Range and Compensation Package
This is a full‑time, on‑site role based in the San Francisco Bay Area, CA. Relocation stipend available. Salary Range: $100,000–$140,000, depending on experience Equity: Meaningful early‑stage equity as part of the founding team Benefits: 401(k) with company matching, healthcare, vision and dental coverage
Equal Opportunity Statement
We’re committed to building a diverse and inclusive team. We welcome applicants of all backgrounds, experiences, and identities. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, sexual orientation, and gender identity), ancestry, marital status, national origin, religion, age, disability, genetic information, veteran status, or any other protected status under applicable laws.
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$100,000.00/yr - $140,000.00/yr
About Us
We’re a stealth-mode, venture-backed biotech startup based in the Bay Area, developing breakthrough technology at the intersection of genetics and reproductive health. We’re backed by world‑class investors, have raised our first institutional round, and are now expanding our team. We operate our primary lab in the Peninsula and we’re in the process of getting access to additional access to world‑class chemistry facilities in the East Bay. Applicants must be willing to commute between campuses.
About the Role
We’re seeking a scientist with deep expertise in nucleic acid analog synthesis and assay development to join our R&D team. In this role, you’ll collaborate closely with our founding team to develop and optimize our cellular assays. You will design and optimize the synthesis of nucleic acid analogs, characterize the synthetic output, and assist in the evaluation of reagent efficacy. This is a hands‑on, high‑impact role at the earliest stage of the company; perfect for someone excited to shape the future of fertility and reproductive health. PhD (or equivalent experience) in organic chemistry, biomolecular chemistry, chemical biology, nucleic acid chemistry, or closely related field required.
Required Skills
Extensive, hands‑on experience with synthetic nucleic acid or peptide chemistry Experience with PNA OR a closely related polymer synthesis workflows and troubleshooting Knowledge of nucleotide or nucleic acid binding principles: hybridization thermodynamics, mismatch discrimination, duplex stability, etc. Proficiency in peptide and nucleic acid purification and characterization via HPLC, LC‑MS, etc Ability to design and interpret in‑vitro / in‑silico binding or stability assays Excellent communication and organizational skills Excited to work in a dynamic, early‑stage startup atmosphere Motivated, independent, and excited to help build new technology Comfort working across multiple lab sites/campuses
Preferred Skills
Experience with in vivo or cellular assays involving nucleic acid probes Knowledge of alternative nucleic acid backbone chemistries (e.g., morpholino, modified RNAs) Prior startup or technology development experience
Pay Range and Compensation Package
This is a full‑time, on‑site role based in the San Francisco Bay Area, CA. Relocation stipend available. Salary Range: $100,000–$140,000, depending on experience Equity: Meaningful early‑stage equity as part of the founding team Benefits: 401(k) with company matching, healthcare, vision and dental coverage
Equal Opportunity Statement
We’re committed to building a diverse and inclusive team. We welcome applicants of all backgrounds, experiences, and identities. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, sexual orientation, and gender identity), ancestry, marital status, national origin, religion, age, disability, genetic information, veteran status, or any other protected status under applicable laws.
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