Alexion Pharmaceuticals, Inc.
Executive Medical Director, Hematology
Alexion Pharmaceuticals, Inc., Boston, Massachusetts, us, 02298
Executive Medical Director, Hematology
Location: Boston, MA or Barcelona, Spain
Overview The Executive Medical Director (EMD) role is responsible for overseeing 2 or more programs, providing oversight, guidance and mentoring to the Medical Directors and Clinical Development Scientists on the teams, serving on cross-asset strategic teams (e.g., disease strategy team) and providing input to strategic decisions at the TA Strategy Team and Global Medicine Team meetings.
The EMD may also support development of regulatory strategy, therapeutic area strategy and other functional strategies.
Responsibilities
Typically leading 2 program teams and driving the successful execution of clinical studies/programs/research strategies; defining and managing the benefit‑to‑risk profile of our products.
Representing Clinical Development on the Global Program Team (GPT) and Global Medicine Team in presentations at management and review committees and advancing scientific understanding of the impact of our therapies on rare and orphan diseases.
Fostering development of Medical Directors and CDS/fellows; leading and overseeing 2 programs and the preparation and execution of a clinical development strategy and related documents including protocols, charters, statistical summaries, meeting presentations, publications and clinical sections of regulatory documents.
Providing scientific and medical input to other R&D, commercial, translational, medicine and business development functions and overseeing clinical activities to support due diligences.
Representing Alexion Clinical Development to internal and external communities.
Overseeing a cross‑functional team that develops the clinical components of the CDP and serving as medical input to the Global Development Team/Subteams and as medical expert for the clinical study team.
Coordinating communications and planning between medical functions (Global Medical Affairs, Safety, Clinical Operations, Biostatistics, Epidemiology, Medical Science) as it relates to study design, execution and interpretation of results.
Serving as the medical expert on the global product labeling team.
Driving awareness of internal and external developments that could impact the development plan, including attendance at major scientific conferences, participation in competitive intelligence activities, and periodic literature review.
Writing or contributing to white papers, expert opinion reports and regulatory responses.
Driving clinical support of business development activities, such as due diligence and research collaborations.
Critically evaluating disease information and the competitive landscape and synthesizing it to support dissemination into clinical development programs, asset plans and therapeutic area strategy.
Determining appropriate advisory board experts.
Working as part of a cross‑functional team with colleagues in biostatistics, data management, clinical pharmacology, commercial, regulatory and project management.
May supervise other medical monitors on individual studies.
Qualifications
Required: M.D. or equivalent.
7+ years of experience in clinical development, clinical research, global regulatory and product development.
Experience preparing documents and attending regulatory meetings with FDA and other regulatory agencies.
Experience designing and executing multinational clinical trials.
Demonstrated ability to lead cross‑functional teams to define clinical strategy and study design.
Experience supporting business development activities.
MD or equivalent, preferably with clinical training.
Ph.D. in a related discipline desirable, but not required.
Duty environment is office‑based; ability to use a computer, communicate via phone, video and electronic messaging, engage in problem solving, collaborate with others and maintain availability during standard business hours.
Preferred
Advanced knowledge of the assigned therapy area, with the capability to interpret, discuss and represent trial or program‑level data.
7+ years of experience in industry in clinical development is preferred.
Posting Dates Date Posted: 14-Dec-2025
Closing Date: 26-Apr-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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Overview The Executive Medical Director (EMD) role is responsible for overseeing 2 or more programs, providing oversight, guidance and mentoring to the Medical Directors and Clinical Development Scientists on the teams, serving on cross-asset strategic teams (e.g., disease strategy team) and providing input to strategic decisions at the TA Strategy Team and Global Medicine Team meetings.
The EMD may also support development of regulatory strategy, therapeutic area strategy and other functional strategies.
Responsibilities
Typically leading 2 program teams and driving the successful execution of clinical studies/programs/research strategies; defining and managing the benefit‑to‑risk profile of our products.
Representing Clinical Development on the Global Program Team (GPT) and Global Medicine Team in presentations at management and review committees and advancing scientific understanding of the impact of our therapies on rare and orphan diseases.
Fostering development of Medical Directors and CDS/fellows; leading and overseeing 2 programs and the preparation and execution of a clinical development strategy and related documents including protocols, charters, statistical summaries, meeting presentations, publications and clinical sections of regulatory documents.
Providing scientific and medical input to other R&D, commercial, translational, medicine and business development functions and overseeing clinical activities to support due diligences.
Representing Alexion Clinical Development to internal and external communities.
Overseeing a cross‑functional team that develops the clinical components of the CDP and serving as medical input to the Global Development Team/Subteams and as medical expert for the clinical study team.
Coordinating communications and planning between medical functions (Global Medical Affairs, Safety, Clinical Operations, Biostatistics, Epidemiology, Medical Science) as it relates to study design, execution and interpretation of results.
Serving as the medical expert on the global product labeling team.
Driving awareness of internal and external developments that could impact the development plan, including attendance at major scientific conferences, participation in competitive intelligence activities, and periodic literature review.
Writing or contributing to white papers, expert opinion reports and regulatory responses.
Driving clinical support of business development activities, such as due diligence and research collaborations.
Critically evaluating disease information and the competitive landscape and synthesizing it to support dissemination into clinical development programs, asset plans and therapeutic area strategy.
Determining appropriate advisory board experts.
Working as part of a cross‑functional team with colleagues in biostatistics, data management, clinical pharmacology, commercial, regulatory and project management.
May supervise other medical monitors on individual studies.
Qualifications
Required: M.D. or equivalent.
7+ years of experience in clinical development, clinical research, global regulatory and product development.
Experience preparing documents and attending regulatory meetings with FDA and other regulatory agencies.
Experience designing and executing multinational clinical trials.
Demonstrated ability to lead cross‑functional teams to define clinical strategy and study design.
Experience supporting business development activities.
MD or equivalent, preferably with clinical training.
Ph.D. in a related discipline desirable, but not required.
Duty environment is office‑based; ability to use a computer, communicate via phone, video and electronic messaging, engage in problem solving, collaborate with others and maintain availability during standard business hours.
Preferred
Advanced knowledge of the assigned therapy area, with the capability to interpret, discuss and represent trial or program‑level data.
7+ years of experience in industry in clinical development is preferred.
Posting Dates Date Posted: 14-Dec-2025
Closing Date: 26-Apr-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
#J-18808-Ljbffr