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Entrada Therapeutics

Manager, Medical Affairs Operations

Entrada Therapeutics, Boston, Massachusetts, us, 02298

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About Entrada Therapeutics

Entrada is a clinical-stage biopharmaceutical company focused on delivering a new class of medicines that engage intracellular targets. Through our Endosomal Escape Vehicle (EEV™) technology, we enable the efficient intracellular delivery of RNA and protein therapeutics for neuromuscular and ocular diseases. Opportunity

The Medical Affairs Operations Lead is a newly created position that reports to the SVP of Medical Affairs. The individual will build and execute the operational infrastructure required to support Entrada’s growing Medical Affairs function across neuromuscular and other therapeutic programs. This role serves as the tactical engine for Medical Affairs—driving operational excellence, cross‑functional alignment, compliant execution, and efficient resource management. Responsibilities

Lead end‑to‑end planning and execution of Medical Affairs activities at scientific and medical congresses (e.g., AAN, MDA, WMS). Manage scientific booth operations, including vendor oversight, logistics, materials development, metrics capture, and post‑congress reporting. Develop and steward a comprehensive annual congress strategy and calendar. Plan, execute, and optimize Medical Affairs team meetings and cross‑functional congress planning meetings. Maintain the Medical Affairs annual strategic plan, key deliverable tracker, and operational KPIs. Own Medical Affairs budget tracking, forecasting, and monthly accruals in partnership with Finance. Manage purchase order creation, approval workflows, vendor contracts, and invoice reconciliation. Develop and implement budget visibility tools (dashboards, trackers) for leadership. Review vendor proposals, SOWs, and contracts for operational feasibility and cost efficiency. Manage the Independent Medical Education (IME) grant process in accordance with Entrada policies and OIG/PhRMA guidance. Oversee investigator‑initiated studies (IIS) and externally sponsored research (ESR) operations, including intake, feasibility review, contract routing, and milestone tracking. Align with Legal, Compliance, and Clinical Operations to ensure appropriate scientific rationale, fair‑market value assessments, and compliant disbursement of funds. Maintain a centralized database of all Medical Affairs–supported grants and funding programs with performance metrics. Qualifications

Bachelor’s degree in a scientific field with 5+ years of experience in the pharmaceutical or biotech industry. 5+ years of experience in Medical Affairs Operations within biotech/pharma; rare disease or RNA therapeutics experience is a plus. Exceptional project management, budgeting, and vendor management skills. Ability to work cross‑functionally, influence without authority, and lead through ambiguity. Highly organized, detail‑oriented, and comfortable operating at both strategic and tactical levels. Ability to travel (US and International) approximately 30 % of time. Hybrid working model: office attendance 2‑3 days per week at the Entrada headquarters in Boston, MA. What We Offer

We provide competitive compensation, comprehensive health benefits, 401(k) match, paid parental leave, education reimbursement, and discretionary time off. Entrada is committed to a culture of inclusion, collaboration, and scientific innovation. Equal Opportunity Employer

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity, expression, age, mental or physical disability, genetic information, marital status, citizenship status, military status, protected veteran status, or any other category protected by law.

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