InsideHigherEd
Post-Doc Research Associate (Kelada Lab)
InsideHigherEd, Chapel Hill, North Carolina, United States, 27517
Position Title: Post-Doc Research Associate (Kelada Lab)
Vacancy ID: PDS004674
Location: Chapel Hill, NC, North Carolina, US
Full-Time Temporary, 40 hours per week, 12-month appointment, proposed start date 01/05/2026.
Benefits UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.
Position Summary The Kelada Lab is seeking a post-doctoral research associate to join their research program on the role of gene-environment interactions with air pollution in respiratory disease. We seek to uncover mechanistic links between the genome (e.g., DNA sequence variants), epigenome (chromatin accessibility), gene expression, and air‑pollutant‑induced airway inflammation phenotypes in a mouse model system. More specifically, our project will leverage genetically diverse mice from the Collaborative Cross mouse genetics reference population to identify quantitative trait loci (QTL) that influence response to the air pollutant ozone. In addition to QTL mapping of ozone response phenotypes, we will also analyze gene expression and chromatin accessibility in key cell types and identify expression and accessibility QTL that mediate the relationships between ozone exposure and response.
We are looking for an enthusiastic post-doctoral research associate to join this project and help lead efforts to generate and analyze these datasets. The post-doctoral research associate will have the opportunity to learn from lab members and other members of the genetics, pulmonary, and toxicology research communities at UNC, which are exceptionally strong. The post-doctoral research associate will also have the opportunity to work with a strong bioinformatics team at UNC to analyze genomic data, and the research project and environment will provide ample opportunities for training in these approaches. In addition to research, the post-doctoral research associate will be actively involved with writing scientific papers and presenting talks at scientific meetings.
Responsibilities
Generate and analyze genomic datasets related to gene‑environment interactions.
Lead efforts to generate and analyze datasets from genetically diverse mouse populations.
Perform QTL mapping of ozone response phenotypes.
Analyze gene expression and chromatin accessibility in key cell types.
Identify expression and accessibility QTL that mediate relationships between ozone exposure and response.
Write scientific papers and present talks at scientific meetings.
Minimum Education and Experience Requirements PhD in Genetics or a related field.
Required Qualifications, Competencies, and Experience
Experience with quantitative genetic analysis (QTL mapping in particular).
Preferred Qualifications, Competencies, and Experience
Experience with mouse models of human disease.
Experience with flow cytometry.
Special Instructions For information on UNC Postdoctoral Benefits and Services click here.
Please provide a sample of scientific writing from graduate training (e.g., published manuscript or chapter from dissertation) in the “Writing Sample” option for required documents.
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Vacancy ID: PDS004674
Location: Chapel Hill, NC, North Carolina, US
Full-Time Temporary, 40 hours per week, 12-month appointment, proposed start date 01/05/2026.
Benefits UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.
Position Summary The Kelada Lab is seeking a post-doctoral research associate to join their research program on the role of gene-environment interactions with air pollution in respiratory disease. We seek to uncover mechanistic links between the genome (e.g., DNA sequence variants), epigenome (chromatin accessibility), gene expression, and air‑pollutant‑induced airway inflammation phenotypes in a mouse model system. More specifically, our project will leverage genetically diverse mice from the Collaborative Cross mouse genetics reference population to identify quantitative trait loci (QTL) that influence response to the air pollutant ozone. In addition to QTL mapping of ozone response phenotypes, we will also analyze gene expression and chromatin accessibility in key cell types and identify expression and accessibility QTL that mediate the relationships between ozone exposure and response.
We are looking for an enthusiastic post-doctoral research associate to join this project and help lead efforts to generate and analyze these datasets. The post-doctoral research associate will have the opportunity to learn from lab members and other members of the genetics, pulmonary, and toxicology research communities at UNC, which are exceptionally strong. The post-doctoral research associate will also have the opportunity to work with a strong bioinformatics team at UNC to analyze genomic data, and the research project and environment will provide ample opportunities for training in these approaches. In addition to research, the post-doctoral research associate will be actively involved with writing scientific papers and presenting talks at scientific meetings.
Responsibilities
Generate and analyze genomic datasets related to gene‑environment interactions.
Lead efforts to generate and analyze datasets from genetically diverse mouse populations.
Perform QTL mapping of ozone response phenotypes.
Analyze gene expression and chromatin accessibility in key cell types.
Identify expression and accessibility QTL that mediate relationships between ozone exposure and response.
Write scientific papers and present talks at scientific meetings.
Minimum Education and Experience Requirements PhD in Genetics or a related field.
Required Qualifications, Competencies, and Experience
Experience with quantitative genetic analysis (QTL mapping in particular).
Preferred Qualifications, Competencies, and Experience
Experience with mouse models of human disease.
Experience with flow cytometry.
Special Instructions For information on UNC Postdoctoral Benefits and Services click here.
Please provide a sample of scientific writing from graduate training (e.g., published manuscript or chapter from dissertation) in the “Writing Sample” option for required documents.
#J-18808-Ljbffr